1KFE

CRYSTAL STRUCTURE OF ALPHAT183V MUTANT OF TRYPTOPHAN SYNTHASE FROM SALMONELLA TYPHIMURIUM WITH L-Ser Bound To The Beta Site

Summary for 1KFE

Related1K8X
DescriptorTRYPTOPHAN SYNTHASE ALPHA CHAIN, TRYPTOPHAN SYNTHASE BETA CHAIN, SODIUM ION, ... (5 entities in total)
Functional Keywordshelix, lyase
Biological sourceSalmonella typhimurium
Total number of polymer chains2
Total molecular weight71601.47
Authors
Kulik, V.,Weyand, M.,Siedel, R.,Niks, D.,Arac, D.,Dunn, M.F.,Schlichting, I. (deposition date: 2001-11-20, release date: 2003-01-07, Last modification date: 2011-07-13)
Primary citation
Kulik, V.,Weyand, M.,Siedel, R.,Niks, D.,Arac, D.,Dunn, M.F.,Schlichting, I.
On the Role of AlphaTHR183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase
J.Mol.Biol., 324:677-690, 2002
PubMed: 12460570 (PDB entries with the same primary citation)
DOI: 10.1016/S0022-2836(02)01109-9
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22540.2%0.4%4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report