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1FUY
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BU of 1fuy by Molmil
CRYSTAL STRUCTURE OF BETAA169L/BETAC170W DOUBLE MUTANT OF TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUORO-INDOLE-PROPANOL PHOSPHATE
Descriptor: 5-FLUOROINDOLE PROPANOL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
Authors:Weyand, M, Schlichting, I.
Deposit date:2000-09-18
Release date:2001-01-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the impaired channeling and allosteric inter-subunit communication in the beta A169L/beta C170W mutant of tryptophan synthase.
J.Biol.Chem., 275, 2000
1QI9
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BU of 1qi9 by Molmil
X-RAY SIRAS STRUCTURE DETERMINATION OF A VANADIUM-DEPENDENT HALOPEROXIDASE FROM ASCOPHYLLUM NODOSUM AT 2.0 A RESOLUTION
Descriptor: VANADATE ION, Vanadium-dependent bromoperoxidase
Authors:Weyand, M, Hecht, H.-J, Kiess, M, Liaud, M.F, Vilter, H, Schomburg, D.
Deposit date:1999-06-10
Release date:2000-06-10
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:X-ray structure determination of a vanadium-dependent haloperoxidase from Ascophyllum nodosum at 2.0 A resolution.
J.Mol.Biol., 293, 1999
8ANB
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BU of 8anb by Molmil
14-3-3 sigma sirtuin-1 phospho-peptide complex
Descriptor: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Weyand, M, Steegborn, C, Debbert, L.
Deposit date:2022-08-05
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:14-3-3 sigma sirtuin-1 phospho-peptide complex
To Be Published
8ANC
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BU of 8anc by Molmil
14-3-3 sigma sirtuin-3 phospho-peptide complex
Descriptor: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
Authors:Weyand, M, Steegborn, C, Debbert, L.
Deposit date:2022-08-05
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:14-3-3 sigma sirtuin-3 phospho-peptide complex
To Be Published
1QOQ
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BU of 1qoq by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH INDOLE GLYCEROL PHOSPHATE
Descriptor: INDOLE-3-GLYCEROL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
Authors:Weyand, M, Schlichting, I.
Deposit date:1999-11-15
Release date:2000-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Wild-Type Tryptophan Synthase Complexed with the Natural Substrate Indole-3-Glycerol Phosphate.
Biochemistry, 38, 1999
1QOP
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BU of 1qop by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH INDOLE PROPANOL PHOSPHATE
Descriptor: INDOLE-3-PROPANOL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
Authors:Weyand, M, Schlichting, I.
Deposit date:1999-11-15
Release date:2000-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of Wild-Type Tryptophan Synthase Complexed with the Natural Substrate Indole-3-Glycerol Phosphate
Biochemistry, 38, 1999
1K7E
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BU of 1k7e by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID
Descriptor: N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
Authors:Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
Deposit date:2001-10-19
Release date:2002-07-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase.
J.Biol.Chem., 277, 2002
1K8Z
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BU of 1k8z by Molmil
CRYSTAL STRUCTURE OF THE TRYPTOPHAN SYNTHASE BETA-SER178PRO MUTANT COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID
Descriptor: N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
Authors:Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
Deposit date:2001-10-26
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
J.Biol.Chem., 277, 2002
1K7F
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BU of 1k7f by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]VALINE ACID
Descriptor: N-[1H-INDOL-3-YL-ACETYL]VALINE ACID, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
Authors:Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
Deposit date:2001-10-19
Release date:2002-07-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase.
J.Biol.Chem., 277, 2002
1K7X
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BU of 1k7x by Molmil
CRYSTAL STRUCTURE OF THE BETA-SER178PRO MUTANT OF TRYPTOPHAN SYNTHASE
Descriptor: PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
Authors:Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
Deposit date:2001-10-22
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
J.Biol.Chem., 277, 2002
1K3U
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BU of 1k3u by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]ASPARTIC ACID
Descriptor: N-[1H-INDOL-3-YL-ACETYL]ASPARTIC ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
Authors:Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
Deposit date:2001-10-04
Release date:2002-07-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase.
J.Biol.Chem., 277, 2002
1K8Y
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BU of 1k8y by Molmil
CRYSTAL STRUCTURE OF THE TRYPTOPHAN SYNTHASE BETA-SER178PRO MUTANT COMPLEXED WITH D,L-ALPHA-GLYCEROL-3-PHOSPHATE
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
Authors:Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A.
Deposit date:2001-10-26
Release date:2002-06-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
J.Biol.Chem., 277, 2002
7NXZ
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BU of 7nxz by Molmil
Synthetic glycoform of Human Interleukin 6
Descriptor: Interleukin-6
Authors:Weyand, M, Unverzagt, C.
Deposit date:2021-03-19
Release date:2021-04-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Natural Glycoforms of Human Interleukin 6 Show Atypical Plasma Clearance.
Angew.Chem.Int.Ed.Engl., 60, 2021
3UAL
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BU of 3ual by Molmil
Crystal Structure of 14-3-3 epsilon with Mlf1 peptide
Descriptor: 14-3-3 protein epsilon, Myeloid leukemia factor 1, TERTIARY-BUTYL ALCOHOL
Authors:Weyand, M, Ottmann, C.
Deposit date:2011-10-21
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights of the MLF1/14-3-3 interaction.
Febs J., 279, 2012
4BUZ
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BU of 4buz by Molmil
SIR2 COMPLEX STRUCTURE MIXTURE OF EX-527 INHIBITOR AND REACTION PRODUCTS OR OF REACTION SUBSTRATES P53 PEPTIDE AND NAD
Descriptor: (1S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1- carboxamide, 1,2-ETHANEDIOL, 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, ...
Authors:Weyand, M, Lakshminarasimhan, M, Gertz, M, Steegborn, C.
Deposit date:2013-06-24
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ex-527 Inhibits Sirtuins by Exploiting Their Unique Nad+-Dependent Deacetylation Mechanism
Proc.Natl.Acad.Sci.USA, 110, 2013
4BGC
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BU of 4bgc by Molmil
T1 domain of the renal potassium channel Kv1.3
Descriptor: POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY A MEMBER 3
Authors:Weyand, M, Kremer, W, Kalbitzer, H.R.
Deposit date:2013-03-25
Release date:2013-10-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:1.2 A X-Ray Structure of the Renal Potassium Channel Kv1.3 T1 Domain.
Protein J., 32, 2013
1Z2C
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BU of 1z2c by Molmil
Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP
Descriptor: Diaphanous protein homolog 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Rose, R, Weyand, M, Lammers, M, Ishizaki, T, Ahmadian, M.R, Wittinghofer, A.
Deposit date:2005-03-08
Release date:2005-05-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and mechanistic insights into the interaction between Rho and mammalian Dia.
Nature, 435, 2005
3GNU
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BU of 3gnu by Molmil
Toxin fold as basis for microbial attack and plant defense
Descriptor: 25 kDa protein elicitor, CHLORIDE ION, GUANIDINE
Authors:Ottmann, C, Luberacki, B, Kuefner, I, Koch, W, Brunner, F, Weyand, M, Mattinen, L, Pirhonen, M, Anderluh, G, Seitz, H.U, Nuernberger, T, Oecking, C.
Deposit date:2009-03-18
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A common toxin fold mediates microbial attack and plant defense
Proc.Natl.Acad.Sci.USA, 106, 2009
3GNZ
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BU of 3gnz by Molmil
Toxin fold for microbial attack and plant defense
Descriptor: 25 kDa protein elicitor, MAGNESIUM ION
Authors:Ottmann, C, Luberacki, B, Kuefner, I, Koch, W, Brunner, F, Weyand, M, Mattinen, L, Pirhonen, M, Anderluh, G, Seitz, H.U, Nuernberger, T, Oecking, C.
Deposit date:2009-03-18
Release date:2009-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:A common toxin fold mediates microbial attack and plant defense
Proc.Natl.Acad.Sci.USA, 106, 2009
3NKX
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BU of 3nkx by Molmil
Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome
Descriptor: 14-3-3 protein zeta/delta, PROPANOIC ACID, Peptide of RAF proto-oncogene serine/threonine-protein kinase
Authors:Schumacher, B, Weyand, M, Ottmann, C.
Deposit date:2010-06-21
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling
Mol.Cell.Biol., 30, 2010
7OBZ
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BU of 7obz by Molmil
Structure of RsLOV D109G
Descriptor: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, LOV protein, ...
Authors:Moeglich, A, Krafft, T.G.A, Weyand, M.
Deposit date:2021-04-25
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Light-Oxygen-Voltage Receptor Integrates Light and Temperature.
J.Mol.Biol., 433, 2021
7OB0
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BU of 7ob0 by Molmil
Structure of RsLOV d2 variant
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN MONONUCLEOTIDE, ...
Authors:Moeglich, A, Krafft, T.G.A, Weyand, M.
Deposit date:2021-04-20
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Light-Oxygen-Voltage Receptor Integrates Light and Temperature.
J.Mol.Biol., 433, 2021
1WBJ
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BU of 1wbj by Molmil
wildtype tryptophan synthase complexed with glycerol phosphate
Descriptor: PYRIDOXAL-5'-PHOSPHATE, SN-GLYCEROL-3-PHOSPHATE, SODIUM ION, ...
Authors:Kulik, V, Weyand, M, Schlichting, I.
Deposit date:2004-11-01
Release date:2006-05-24
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:On the Structural Basis of the Catalytic Mechanism and the Regulation of the Alpha Subunit of Tryptophan Synthase from Salmonella Typhimurium and Bx1 from Maize, Two Evolutionarily Related Enzymes.
J.Mol.Biol., 352, 2005
3IQU
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BU of 3iqu by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (6mer)
Descriptor: 14-3-3 protein sigma, 6-mer from RAF proto-oncogene serine/threonine-protein kinase, CHLORIDE ION, ...
Authors:Ottmann, C, Weyand, M.
Deposit date:2009-08-21
Release date:2010-09-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010
3IQJ
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BU of 3iqj by Molmil
Crystal Structure of human 14-3-3 sigma in Complex with Raf1 peptide (10mer)
Descriptor: 10-mer peptide from RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, CHLORIDE ION, ...
Authors:Ottmann, C, Weyand, M.
Deposit date:2009-08-20
Release date:2010-09-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol., 30, 2010

 

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