8CG8
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![BU of 8cg8 by Molmil](/molmil-images/mine/8cg8) | Translocation intermediate 3 (TI-3) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | Deposit date: | 2023-02-03 | Release date: | 2023-09-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
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8CEH
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![BU of 8ceh by Molmil](/molmil-images/mine/8ceh) | Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | Deposit date: | 2023-02-01 | Release date: | 2023-09-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.05 Å) | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
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6IDH
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![BU of 6idh by Molmil](/molmil-images/mine/6idh) | Antibody 64M-5 Fab in ligand-free form | Descriptor: | Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain) | Authors: | Yokoyama, H, Mizutani, R, Noguchi, S, Hayashida, N. | Deposit date: | 2018-09-10 | Release date: | 2019-02-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of the antibody 64M-5 Fab and its complex with dT(6-4)T indicate induced-fit and high-affinity mechanisms. Acta Crystallogr.,Sect.F, 75, 2019
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8CM6
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![BU of 8cm6 by Molmil](/molmil-images/mine/8cm6) | W-formate dehydrogenase C872A from Desulfovibrio vulgaris - with Formamide | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, CHLORIDE ION, ... | Authors: | Vilela-Alves, G, Mota, C, Oliveira, A.R, Manuel, R.R, Pereira, I.C, Romao, M.J. | Deposit date: | 2023-02-17 | Release date: | 2023-09-27 | Last modified: | 2024-01-03 | Method: | X-RAY DIFFRACTION (1.416 Å) | Cite: | An allosteric redox switch involved in oxygen protection in a CO 2 reductase. Nat.Chem.Biol., 20, 2024
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8CM5
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![BU of 8cm5 by Molmil](/molmil-images/mine/8cm5) | W-formate dehydrogenase C872A from Desulfovibrio vulgaris | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, Formate dehydrogenase, ... | Authors: | Vilela-Alves, G, Mota, C, Klymanska, K, Oliveira, A.R, Manuel, R.R, Pereira, I.C, Romao, M.J. | Deposit date: | 2023-02-17 | Release date: | 2023-09-27 | Last modified: | 2024-01-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | An allosteric redox switch involved in oxygen protection in a CO 2 reductase. Nat.Chem.Biol., 20, 2024
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1ESY
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2J4D
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![BU of 2j4d by Molmil](/molmil-images/mine/2j4d) | Cryptochrome 3 from Arabidopsis thaliana | Descriptor: | 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, CRYPTOCHROME DASH, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Klar, T, Pokorny, R, Batschauer, A, Essen, L.-O. | Deposit date: | 2006-08-28 | Release date: | 2007-06-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cryptochrome 3 from Arabidopsis Thaliana: Structural and Functional Analysis of its Complex with a Folate Light Antenna J.Mol.Biol., 366, 2007
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8C6K
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![BU of 8c6k by Molmil](/molmil-images/mine/8c6k) | Double mutant A(L53)C/I(L64)C structure of Photosynthetic Reaction Center From Cereibacter sphaeroides strain RV | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, BACTERIOCHLOROPHYLL A, ... | Authors: | Gabdulkhakov, A, Selikhanov, G, Fufina, T, Vasilieva, L, Atamas, A, Uhimchuk, D. | Deposit date: | 2023-01-12 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Stabilization of Cereibacter sphaeroides Photosynthetic Reaction Center by the Introduction of Disulfide Bonds. Membranes (Basel), 13, 2023
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8C5X
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![BU of 8c5x by Molmil](/molmil-images/mine/8c5x) | Double mutant A(L37)C/S(L99)C structure of Photosynthetic Reaction Center From Cereibacter sphaeroides strain RV | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, BACTERIOCHLOROPHYLL A, ... | Authors: | Gabdulkhakov, A, Selikhanov, G, Fufina, T, Vasilieva, L, Atamas, A, Uhimchuk, D. | Deposit date: | 2023-01-10 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Stabilization of Cereibacter sphaeroides Photosynthetic Reaction Center by the Introduction of Disulfide Bonds. Membranes (Basel), 13, 2023
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8C3O
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![BU of 8c3o by Molmil](/molmil-images/mine/8c3o) | Crystal structure of autotaxin gamma and compound MEY-003 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5,7-bis(oxidanyl)-2-(1-pentylindol-3-yl)chromen-4-one, 7alpha-hydroxycholesterol, ... | Authors: | Eymery, M.C, McCarthy, A.A. | Deposit date: | 2022-12-27 | Release date: | 2023-11-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Discovery of potent chromone-based autotaxin inhibitors inspired by cannabinoids. Eur.J.Med.Chem., 263, 2023
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4QDI
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![BU of 4qdi by Molmil](/molmil-images/mine/4qdi) | Crystal structure II of MurF from Acinetobacter baumannii | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | An, Y.J, Jeong, C.S, Cha, S.S. | Deposit date: | 2014-05-13 | Release date: | 2015-04-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | ATP-binding mode including a carbamoylated lysine and two Mg(2+) ions, and substrate-binding mode in Acinetobacter baumannii MurF Biochem.Biophys.Res.Commun., 450, 2014
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8CKB
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![BU of 8ckb by Molmil](/molmil-images/mine/8ckb) | Asymmetric reconstruction of the crAss001 virion | Descriptor: | Auxiliary capsid protein gp36, Cargo protein 1 gp45, Head fiber dimer protein gp29, ... | Authors: | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | Deposit date: | 2023-02-16 | Release date: | 2023-11-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.39 Å) | Cite: | Structural atlas of the most abundant human gut virus Nature
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4PX9
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![BU of 4px9 by Molmil](/molmil-images/mine/4px9) | DEAD-box RNA helicase DDX3X Domain 1 with N-terminal ATP-binding Loop | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX3X | Authors: | Epling, L.B, Grace, C.R, Lowe, B.R, Partridge, J.F, Enemark, E.J. | Deposit date: | 2014-03-22 | Release date: | 2015-03-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Cancer-Associated Mutants of RNA Helicase DDX3X Are Defective in RNA-Stimulated ATP Hydrolysis. J.Mol.Biol., 427, 2015
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2J0E
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![BU of 2j0e by Molmil](/molmil-images/mine/2j0e) | Three dimensional structure and catalytic mechanism of 6- phosphogluconolactonase from Trypanosoma brucei | Descriptor: | 6-PHOSPHOGLUCONOLACTONASE, MERCURY (II) ION, POTASSIUM ION, ... | Authors: | Delarue, M, Duclert-Savatier, N, Miclet, E, Haouz, A, Giganti, D, Ouazzani, J, Lopez, P, Nilges, M, Stoven, V. | Deposit date: | 2006-08-02 | Release date: | 2007-01-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three Dimensional Structure and Implications for the Catalytic Mechanism of 6-Phosphogluconolactonase from Trypanosoma Brucei. J.Mol.Biol., 366, 2007
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4PZP
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8CA5
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![BU of 8ca5 by Molmil](/molmil-images/mine/8ca5) | Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 3). | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | Deposit date: | 2023-01-24 | Release date: | 2023-12-20 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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8C2S
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![BU of 8c2s by Molmil](/molmil-images/mine/8c2s) | Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 1). | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | Deposit date: | 2022-12-22 | Release date: | 2023-12-20 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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8CA3
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![BU of 8ca3 by Molmil](/molmil-images/mine/8ca3) | Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2). | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | Deposit date: | 2023-01-24 | Release date: | 2023-12-20 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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6IZN
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![BU of 6izn by Molmil](/molmil-images/mine/6izn) | Crystal structure of the PPARgamma-LBD complexed with compound 3g | Descriptor: | 3-[[6-(2,6-dimethylpyridin-3-yl)oxy-7-fluoranyl-1-methyl-benzimidazol-2-yl]methoxy]benzoic acid, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Peroxisome proliferator-activated receptor gamma | Authors: | Matsui, Y, Hanzawa, H. | Deposit date: | 2018-12-20 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure-Activity Relationship Studies of 3- or 4-Pyridine Derivatives of DS-6930. Acs Med.Chem.Lett., 10, 2019
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8COU
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![BU of 8cou by Molmil](/molmil-images/mine/8cou) | Pa.FabF-C164Q in complex with 3-acetamido-4-methoxybenzoic acid | Descriptor: | 3-acetamido-4-methoxy-benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ... | Authors: | Georgiou, C, Brenk, R. | Deposit date: | 2023-02-28 | Release date: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023
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8BZ7
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8C3G
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![BU of 8c3g by Molmil](/molmil-images/mine/8c3g) | Crystal structure of DYRK1A in complex with AZ191 | Descriptor: | 1,2-ETHANEDIOL, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine, ... | Authors: | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | Deposit date: | 2022-12-23 | Release date: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural perspective on the design of selective DYRK1B inhibitors To Be Published
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8BZ6
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8BZL
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![BU of 8bzl by Molmil](/molmil-images/mine/8bzl) | Human 20S Proteasome in complex with peptide activator peptide BLM42 | Descriptor: | ARG-SER-TYR-TYR-SER, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Henneberg, F, Chari, A, Jankowska, E, Witkowska, J. | Deposit date: | 2022-12-15 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Peptidic, Blm10-based activators of human 20S proteasome in vitro and in cellulo enhance degradation of proteins connected with neurodegeneration. To Be Published
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8C0H
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