8CA5

Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 3).

Summary for 8CA5

• Entry DOI: 10.2210/pdb8ca5/pdb
• Related: 8C2S 8CA1 8CA2 8CA4
• EMDB information: 16518
• Descriptor: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, NADH-ubiquinone oxidoreductase chain 6, ... (53 entities in total)
• Functional Keywords: nadh ubiquinone oxidoreductase, complex i, oxidoreductase
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 43
• Total formula weight: 1039115.22

Authors

Yin, Z.,Bridges, H.R.,Agip, A.N.A.,Hirst, J. (deposition date: 2023-01-24, release date: 2023-12-20, Last modification date: 2024-01-31)

• Primary citation: Yin, Z.,Agip, A.A.,Bridges, H.R.,Hirst, J.; Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse.; Embo J., 43:225-249, 2024; PubMed: 38177503; DOI: 10.1038/s44318-023-00001-4

Experimental method

ELECTRON MICROSCOPY (3.9 Å)