8BZL

Human 20S Proteasome in complex with peptide activator peptide BLM42

Summary for 8BZL

• Entry DOI: 10.2210/pdb8bzl/pdb
• Related: 5LE5
• Descriptor: Proteasome subunit beta type-3, Proteasome subunit beta type-2, Proteasome subunit beta type-5, ... (20 entities in total)
• Functional Keywords: activator peptide, 20s proteasome, protein degradation, threonine protease, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 34
• Total formula weight: 777602.30

Authors

Henneberg, F.,Chari, A.,Jankowska, E.,Witkowska, J. (deposition date: 2022-12-15, release date: 2023-12-27)

• Primary citation: Gizynska, M.,Karpowicz, P.,Sowik, D.,Trepczyk, K.,Witkowska, J.,Hennenberg, F.,Chari, A.,Gieldon, A.,Pierzynowska, K.,Gaffke, L.,Wegrzyn, G.,Jankowska, E.; Peptidic, Blm10-based activators of human 20S proteasome in vitro and in cellulo enhance degradation of proteins connected with neurodegeneration.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.14 Å)