5ZHV
 
 | | Crystal structure of the PadR-family transcriptional regulator Rv3488 of Mycobacterium tuberculosis H37Rv in complex with zinc ion | | Descriptor: | Transcriptional regulator, ZINC ION | | Authors: | Meera, K, Pal, R.K, Arora, A, Biswal, B.K. | | Deposit date: | 2018-03-13 | | Release date: | 2018-10-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and functional characterization of the transcriptional regulator Rv3488 ofMycobacterium tuberculosisH37Rv.
Biochem. J., 475, 2018
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5Z4J
 | | Structure of Tailor in complex with U4 RNA | | Descriptor: | RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor | | Authors: | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | Deposit date: | 2018-01-11 | | Release date: | 2018-10-31 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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3QPH
 | | The three-dimensional structure of TrmB, a global transcriptional regulator of the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose | | Descriptor: | ACETATE ION, GLYCEROL, TrmB, ... | | Authors: | Krug, M, Lee, S.-J, Boos, W, Welte, W, Diederichs, K. | | Deposit date: | 2011-02-13 | | Release date: | 2012-05-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.992 Å) | | Cite: | The three-dimensional structure of TrmB, a transcriptional regulator of dual function in the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose.
Protein Sci., 22, 2013
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3C2I
 | | The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF | | Descriptor: | DNA (5'-D(*DAP*DTP*DAP*DGP*DAP*DAP*DGP*DAP*DAP*DTP*DTP*DCP*(5CM)P*DGP*DTP*DTP*DCP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DCP*DTP*DGP*DGP*DAP*DAP*(5CM)P*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DTP*DTP*DCP*DTP*DA)-3'), Methyl-CpG-binding protein 2 | | Authors: | Ho, K.L, McNae, I.W, Schmiedeberg, L, Klose, R.J, Bird, A.P, Walkinshaw, M.D. | | Deposit date: | 2008-01-25 | | Release date: | 2008-05-13 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | MeCP2 binding to DNA depends upon hydration at methyl-CpG
Mol.Cell, 29, 2008
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6AJN
 | | Crystal structure of AtaTR bound with AcCoA | | Descriptor: | ACETYL COENZYME *A, DUF1778 domain-containing protein, N-acetyltransferase | | Authors: | Yashiro, Y, Yamashita, S, Tomita, K. | | Deposit date: | 2018-08-28 | | Release date: | 2019-01-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.302 Å) | | Cite: | Crystal Structure of the Enterohemorrhagic Escherichia coli AtaT-AtaR Toxin-Antitoxin Complex.
Structure, 27, 2019
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4JG3
 | | Crystal structure of catabolite repression control protein (crc) from Pseudomonas aeruginosa | | Descriptor: | CHLORIDE ION, Catabolite repression control protein | | Authors: | Grishkovskaya, I, Milojevic, T, Sonnleitner, E, Blaesi, U, Djinovic-Carugo, K. | | Deposit date: | 2013-02-28 | | Release date: | 2013-06-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Pseudomonas aeruginosa Catabolite Repression Control Protein Crc Is Devoid of RNA Binding Activity
Plos One, 8, 2013
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5E57
 | | Crystal structure of Mycobacterium smegmatis AmtR | | Descriptor: | ACETATE ION, Transcription regulator AmtR | | Authors: | Vickers, C.J, McKenzie, J.L, Arcus, V.L. | | Deposit date: | 2015-10-07 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure and Function of AmtR in Mycobacterium smegmatis: Implications for Post-Transcriptional Regulation of Urea Metabolism through a Small Antisense RNA.
J.Mol.Biol., 428, 2016
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6A4W
 | | AcrR from Mycobacterium tuberculosis | | Descriptor: | GLYCEROL, SODIUM ION, SULFATE ION, ... | | Authors: | Kang, S.M, Kim, D.H. | | Deposit date: | 2018-06-21 | | Release date: | 2019-06-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.587 Å) | | Cite: | The crystal structure of AcrR from Mycobacterium tuberculosis reveals a one-component transcriptional regulation mechanism.
Febs Open Bio, 9, 2019
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6AJM
 | | Crystal structure of apo AtaTR | | Descriptor: | DUF1778 domain-containing protein, N-acetyltransferase, TRIETHYLENE GLYCOL | | Authors: | Yashiro, Y, Yamashita, S, Tomita, K. | | Deposit date: | 2018-08-28 | | Release date: | 2019-01-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | Crystal Structure of the Enterohemorrhagic Escherichia coli AtaT-AtaR Toxin-Antitoxin Complex.
Structure, 27, 2019
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5Z4A
 | | Structure of Tailor in complex with AGU RNA | | Descriptor: | RNA (5'-R(*AP*GP*U)-3'), Terminal uridylyltransferase Tailor | | Authors: | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | Deposit date: | 2018-01-10 | | Release date: | 2018-10-31 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.637 Å) | | Cite: | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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1HW2
 | | FADR-DNA COMPLEX: TRANSCRIPTIONAL CONTROL OF FATTY ACID METABOLISM IN ECHERICHIA COLI | | Descriptor: | 5'-D(*CP*GP*AP*TP*CP*TP*GP*GP*TP*CP*CP*GP*AP*CP*CP*AP*GP*AP*TP*GP*CP*T)-3', 5'-D(*G*CP*AP*TP*CP*TP*GP*GP*TP*CP*GP*GP*AP*CP*CP*AP*GP*AP*TP*CP*GP*A)-3', FATTY ACID METABOLISM REGULATOR PROTEIN, ... | | Authors: | Xu, Y, Heath, R.J, Li, Z, Rock, C.O, White, S.W. | | Deposit date: | 2001-01-09 | | Release date: | 2001-01-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | The FadR.DNA complex. Transcriptional control of fatty acid metabolism in Escherichia coli.
J.Biol.Chem., 276, 2001
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5Z8N
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5ZI8
 | | Crystal structure of the PadR-family transcriptional regulator Rv3488 of Mycobacterium tuberculosis H37Rv in complex with cadmium ion | | Descriptor: | CADMIUM ION, Transcriptional regulator | | Authors: | Meera, K, pal, R.K, Arora, A, Biswal, B.K. | | Deposit date: | 2018-03-14 | | Release date: | 2018-10-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and functional characterization of the transcriptional regulator Rv3488 ofMycobacterium tuberculosisH37Rv.
Biochem. J., 475, 2018
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5Y4U
 | | Crystal structure of Grx domain of Grx3 from Saccharomyces cerevisiae | | Descriptor: | Monothiol glutaredoxin-3 | | Authors: | Chi, C.B, Tang, Y.J, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2017-08-05 | | Release date: | 2018-08-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3.
J.Mol.Biol., 430, 2018
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5ZHC
 | | Crystal structure of the PadR-family transcriptional regulator Rv3488 of Mycobacterium tuberculosis H37Rv | | Descriptor: | ACETATE ION, CHLORIDE ION, Transcriptional regulator | | Authors: | Meera, K, Pal, R.K, Arora, A, Biswal, B.K. | | Deposit date: | 2018-03-12 | | Release date: | 2018-10-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structural and functional characterization of the transcriptional regulator Rv3488 ofMycobacterium tuberculosisH37Rv.
Biochem. J., 475, 2018
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2F3X
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1RVU
 | | E75Q MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE | | Descriptor: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, ... | | Authors: | Szebenyi, D.M, Musayev, F.N, Di Salvo, M.L, Safo, M.K, Schirch, V. | | Deposit date: | 2003-12-15 | | Release date: | 2004-06-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism.
Biochemistry, 43, 2004
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3CVA
 | | Human Bcl-xL containing a Trp to Ala mutation at position 137 | | Descriptor: | Apoptosis regulator Bcl-X | | Authors: | Feng, Y, Zhang, L, Hu, T, Shen, X, Chen, K, Jiang, H, Liu, D. | | Deposit date: | 2008-04-18 | | Release date: | 2009-03-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A conserved hydrophobic core at Bcl-x(L) mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein
Arch.Biochem.Biophys., 484, 2009
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2Y48
 | | Crystal structure of LSD1-CoREST in complex with a N-terminal SNAIL peptide | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC DEMETHYLASE 1A, REST COREPRESSOR 1, ... | | Authors: | Baron, R, Binda, C, Tortorici, M, McCammon, J.A, Mattevi, A. | | Deposit date: | 2011-01-05 | | Release date: | 2011-02-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase Lsd1-Corest Complex.
Structure, 19, 2011
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7KWM
 | | CtBP1 (28-375) L182F/V185T - AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, C-terminal-binding protein 1, CALCIUM ION | | Authors: | Royer, W.E, Del Campo, M. | | Deposit date: | 2020-12-01 | | Release date: | 2021-02-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).
J.Biol.Chem., 296, 2021
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5ICN
 | | HDAC1:MTA1 in complex with inositol-6-phosphate and a novel peptide inhibitor based on histone H4 | | Descriptor: | GLY-ALA-6A0-ARG-HIS, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Millard, C.J, Robertson, N.S, Watson, P.J, Jameson, A.G, Schwabe, J.W.R. | | Deposit date: | 2016-02-23 | | Release date: | 2016-05-11 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.
Nat Commun, 7, 2016
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1HZW
 | | CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE | | Descriptor: | PHOSPHATE ION, THYMIDYLATE SYNTHASE | | Authors: | Almog, R, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P. | | Deposit date: | 2001-01-26 | | Release date: | 2001-05-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Protein Sci., 10, 2001
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1I00
 | | CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE, TERNARY COMPLEX WITH DUMP AND TOMUDEX | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | | Authors: | Almog, R.A, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P. | | Deposit date: | 2001-01-27 | | Release date: | 2001-05-09 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Protein Sci., 10, 2001
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2VXF
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1RV3
 | | E75L MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE, COMPLEX WITH GLYCINE | | Descriptor: | GLYCINE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Szebenyi, D.M, Musayev, F.N, di Salvo, M.L, Safo, M.K, Schirch, V. | | Deposit date: | 2003-12-12 | | Release date: | 2004-06-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism.
Biochemistry, 43, 2004
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