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2JQL
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BU of 2jql by Molmil
NMR structure of the yeast Dun1 FHA domain in complex with a doubly phosphorylated (pT) peptide derived from Rad53 SCD1
Descriptor: DNA damage response protein kinase DUN1, Serine/threonine-protein kinase RAD53
Authors:Yuan, C, Lee, H, Chang, C, Heierhorst, J, Tsai, M.
Deposit date:2007-06-02
Release date:2008-06-24
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade.
Mol.Cell, 30, 2008
1J39
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BU of 1j39 by Molmil
Crystal Structure of T4 phage BGT in complex with its UDP-glucose substrate
Descriptor: DNA beta-glucosyltransferase, GLYCEROL, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Lariviere, L, Morera, S.
Deposit date:2003-01-21
Release date:2003-08-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism.
J.Mol.Biol., 330, 2003
2JQJ
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BU of 2jqj by Molmil
NMR structure of yeast Dun1 FHA domain
Descriptor: DNA damage response protein kinase DUN1
Authors:Yuan, C, Lee, H, Chang, C, Heierhorst, J, Tsai, M.
Deposit date:2007-06-02
Release date:2008-06-24
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade.
Mol.Cell, 30, 2008
7YOX
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BU of 7yox by Molmil
Cryo-EM structure of the N-terminal domain of hMCM8/9 and HROB
Descriptor: DNA helicase MCM8, DNA helicase MCM9
Authors:Zheng, J.F, Weng, Z.F, Liu, Y.F.
Deposit date:2022-08-02
Release date:2023-08-09
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural and mechanistic insights into the MCM8/9 helicase complex.
Elife, 12, 2023
1QV4
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BU of 1qv4 by Molmil
B-DNA Dodecamer CGTGAATTCACG complexed with minor groove binder methylproamine
Descriptor: 2'-(3-METHYL-4-DIMETHYLAMINOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'
Authors:Squire, C.J, Clark, G.R.
Deposit date:2003-08-26
Release date:2004-09-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:In vitro studies with methylproamine: a potent new radioprotector.
Cancer Res., 64, 2004
1QV8
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B-DNA Dodecamer d(CGCGAATTCGCG)2 complexed with proamine
Descriptor: 2'-(4-DIMETHYLAMINOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'
Authors:Squire, C.J, Clark, G.R.
Deposit date:2003-08-27
Release date:2004-09-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:In vitro studies with methylproamine: a potent new radioprotector.
Cancer Res., 64, 2004
2MC6
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BU of 2mc6 by Molmil
A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement
Descriptor: DNA-directed RNA polymerase subunit beta', RNA polymerase inhibitor p7
Authors:Liu, B, Shadrin, A, Sheppard, C, Xu, Y, Severinov, K, Matthews, S, Wigneshweraraj, S.
Deposit date:2013-08-15
Release date:2014-04-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement.
Nucleic Acids Res., 42, 2014
3VKE
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BU of 3vke by Molmil
Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
Descriptor: DNA (5'-D(P*AP*CP*CP*CP*CP*A)-3'), Poly(rC)-binding protein 1
Authors:Traore, D.A.K, Wilce, M.C.J, Wilce, J.A.
Deposit date:2011-11-15
Release date:2012-02-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
Nucleic Acids Res., 40, 2012
1NXR
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HIV-1 POLYPURINE HYBRID, R(GAGGACUG):D(CAGTCCTC), NMR, 18 STRUCTURES
Descriptor: DNA (5'-D(*CP*AP*GP*TP*CP*CP*TP*C)-3'), RNA (5'-R(*GP*AP*GP*GP*AP*CP*UP*G)-3')
Authors:Fedoroff, O.Y, Ge, Y, Reid, B.R.
Deposit date:1997-02-21
Release date:1997-07-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of r(gaggacug):d(CAGTCCTC) hybrid: implications for the initiation of HIV-1 (+)-strand synthesis.
J.Mol.Biol., 269, 1997
6JOU
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BU of 6jou by Molmil
Crystal structure of the human nucleosome containing H2A.Z.1 S42R
Descriptor: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ...
Authors:Horikoshi, N, Sato, K, Mizukami, Y, Kurumizaka, H.
Deposit date:2019-03-23
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo.
Biochem.Biophys.Res.Commun., 515, 2019
6FY7
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Concerted dynamics of metallo-base pairs in an A/B-form helical transition (minor species)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*CP*AP*TP*GP*AP*TP*AP*CP*G)-3')_minor, MERCURY (II) ION
Authors:Schmidt, O.P, Jurt, S, Johannsen, S, Karimi, A, Sigel, R.K.O, Luedtke, N.W.
Deposit date:2018-03-11
Release date:2019-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Concerted dynamics of metallo-base pairs in an A/B-form helical transition.
Nat Commun, 10, 2019
7W7P
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BU of 7w7p by Molmil
Cryo-EM structure of gMCM8/9 helicase
Descriptor: DNA helicase MCM8, DNA helicase MCM9
Authors:Zheng, J.F, Weng, Z.F, Liu, Y.F.
Deposit date:2021-12-06
Release date:2023-05-24
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural and mechanistic insights into the MCM8/9 helicase complex.
Elife, 12, 2023
5EKF
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BU of 5ekf by Molmil
Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 1
Descriptor: DNA repair protein complementing XP-G cells, Importin subunit alpha-1
Authors:Barros, A.C, Takeda, A.A.S, Fontes, M.R.M.
Deposit date:2015-11-03
Release date:2016-02-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence.
J.Mol.Biol., 428, 2016
5GOX
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BU of 5gox by Molmil
Eukaryotic Rad50 Functions as A Rod-shaped Dimer
Descriptor: DNA repair protein RAD50, GLYCEROL, ZINC ION
Authors:Park, Y.B, Hohl, M, Padjasek, M, Jeong, E, Jin, K.S, Krezel, A, Petrini, J.H.J, Cho, Y.
Deposit date:2016-07-30
Release date:2017-02-01
Last modified:2017-03-15
Method:X-RAY DIFFRACTION (2.405 Å)
Cite:Eukaryotic Rad50 functions as a rod-shaped dimer
Nat. Struct. Mol. Biol., 24, 2017
6FY6
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BU of 6fy6 by Molmil
Concerted dynamics of metallo-base pairs in an A/B-form helical transition (major species)
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*CP*AP*TP*GP*AP*TP*AP*CP*G)-3')_major, MERCURY (II) ION
Authors:Schmidt, O.P, Jurt, S, Johannsen, S, Karimi, A, Sigel, R.K.O, Luedtke, N.W.
Deposit date:2018-03-11
Release date:2019-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Concerted dynamics of metallo-base pairs in an A/B-form helical transition.
Nat Commun, 10, 2019
8E2P
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BU of 8e2p by Molmil
Crystal structure of TadA*8.20 in a complex with ssDNA
Descriptor: DNA (5'-D(P*GP*CP*TP*CP*GP*GP*CP*TP*(D8A)P*CP*GP*GP*A)-3'), ZINC ION, tRNA-specific adenosine deaminase 8.20
Authors:Feliciano, P.R, Lee, S.J, Ciaramella, G.
Deposit date:2022-08-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Improved cytosine base editors generated from TadA variants.
Nat.Biotechnol., 41, 2023
8E2Q
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BU of 8e2q by Molmil
Crystal structure of TadAC-1.17 in a complex with ssDNA
Descriptor: DNA (5'-D(P*GP*CP*GP*GP*CP*TP*(D8A)P*CP*GP*GP*A)-3'), GLYCEROL, ZINC ION, ...
Authors:Feliciano, P.R, Lee, S.J, Ciaramella, G.
Deposit date:2022-08-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Improved cytosine base editors generated from TadA variants.
Nat.Biotechnol., 41, 2023
2KLQ
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BU of 2klq by Molmil
The solution structure of CBD of human MCM6
Descriptor: DNA replication licensing factor MCM6
Authors:Liu, C.
Deposit date:2009-07-08
Release date:2010-03-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6
J.Biol.Chem., 285, 2010
6JWE
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BU of 6jwe by Molmil
structure of RET G-quadruplex in complex with colchicine
Descriptor: DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide
Authors:Wang, F, Wang, C, Liu, Y, Lan, W.X, Li, Y.M, Wang, R.X, Cao, C.
Deposit date:2019-04-20
Release date:2020-02-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR.
Chem.Commun.(Camb.), 56, 2020
5BO0
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BU of 5bo0 by Molmil
Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.2-H4 dimer
Descriptor: DNA replication licensing factor MCM2, GLYCEROL, Histone H3.2, ...
Authors:Huang, H, Patel, D.J.
Deposit date:2015-05-26
Release date:2015-06-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
2MWZ
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BU of 2mwz by Molmil
Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G G X O tetrad
Descriptor: DNA (5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*(8OG)P*GP*GP*TP*TP*AP*GP*GP*(3ZO)P*TP*TP*AP*GP*GP*GP*A)-3')
Authors:Cheong, V.V, Heddi, B, Lech, C.J, Phan, A.T.
Deposit date:2014-12-04
Release date:2015-10-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Xanthine and 8-oxoguanine in G-quadruplexes: formation of a GGXO tetrad.
Nucleic Acids Res., 43, 2015
2B2T
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BU of 2b2t by Molmil
Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3
Descriptor: Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail
Authors:Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2W
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BU of 2b2w by Molmil
Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4
Descriptor: Chromodomain-helicase-DNA-binding protein 1, Histone H3
Authors:Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
5AV5
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BU of 5av5 by Molmil
human nucleosome core particle
Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
Deposit date:2015-06-11
Release date:2015-12-23
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
5BNX
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BU of 5bnx by Molmil
Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.3-H4 dimer
Descriptor: DNA replication licensing factor MCM2, GLYCEROL, Histone H3.3, ...
Authors:Huang, H, Patel, D.J.
Deposit date:2015-05-26
Release date:2015-06-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.305 Å)
Cite:A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015

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数据于2024-09-04公开中

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