6JWE
structure of RET G-quadruplex in complex with colchicine
Summary for 6JWE
Entry DOI | 10.2210/pdb6jwe/pdb |
Related | 2L88 |
Descriptor | DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide (2 entities in total) |
Functional Keywords | ret, g-quadruplex, colchicine, dna |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 6793.51 |
Authors | |
Primary citation | Wang, F.,Wang, C.,Liu, Y.,Lan, W.,Han, H.,Wang, R.,Huang, S.,Cao, C. Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR. Chem.Commun.(Camb.), 56:2099-2102, 2020 Cited by PubMed: 32025680DOI: 10.1039/d0cc00221f PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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