6V4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v4x by Molmil](/molmil-images/mine/6v4x) | Cryo-EM structure of an active human histone pre-mRNA 3'-end processing machinery at 3.2 Angstrom resolution | Descriptor: | Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 3, Small nuclear ribonucleoprotein E, ... | Authors: | Sun, Y, Zhang, Y, Walz, T, Tong, L. | Deposit date: | 2019-12-02 | Release date: | 2020-02-19 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of an active human histone pre-mRNA 3'-end processing machinery. Science, 367, 2020
|
|
8FLJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8flj by Molmil](/molmil-images/mine/8flj) | Cas1-Cas2/3 integrase and IHF bound to CRISPR leader, repeat and foreign DNA | Descriptor: | CRISPR leader and repeat, anti-sense strand of DNA, CRISPR leader, ... | Authors: | Santiago-Frangos, A, Henriques, W.S, Wiegand, T, Gauvin, C, Buyukyoruk, M, Neselu, K, Eng, E.T, Lander, G.C, Wiedenheft, B. | Deposit date: | 2022-12-21 | Release date: | 2023-09-06 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays. Nat.Struct.Mol.Biol., 30, 2023
|
|
1DR5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dr5 by Molmil](/molmil-images/mine/1dr5) | CRYSTAL STRUCTURES OF ORGANOMERCURIAL-ACTIVATED CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXES | Descriptor: | CALCIUM ION, DIHYDROFOLATE REDUCTASE, MERCURY (II) ION, ... | Authors: | Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J. | Deposit date: | 1992-03-14 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes To be Published
|
|
1DR3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dr3 by Molmil](/molmil-images/mine/1dr3) | 2.3 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH THIONADP+ AND BIOPTERIN | Descriptor: | 7,8-DIHYDROBIOPTERIN, 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ... | Authors: | Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J. | Deposit date: | 1992-03-14 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes. Biochemistry, 32, 1993
|
|
6VAK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vak by Molmil](/molmil-images/mine/6vak) | Cryo-EM structure of human CALHM2 | Descriptor: | Calcium homeostasis modulator protein 2 | Authors: | Syrjanen, J.L, Chou, T.H, Furukawa, H. | Deposit date: | 2019-12-17 | Release date: | 2020-01-29 | Last modified: | 2020-02-26 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structure and assembly of calcium homeostasis modulator proteins. Nat.Struct.Mol.Biol., 27, 2020
|
|
1DR2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dr2 by Molmil](/molmil-images/mine/1dr2) | 2.3 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH THIONADP+ AND BIOPTERIN | Descriptor: | 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, DIHYDROFOLATE REDUCTASE | Authors: | Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J. | Deposit date: | 1992-03-14 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes. Biochemistry, 32, 1993
|
|
1DR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dr4 by Molmil](/molmil-images/mine/1dr4) | CRYSTAL STRUCTURES OF ORGANOMERCURIAL-ACTIVATED CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXES | Descriptor: | 7,8-DIHYDROBIOPTERIN, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ... | Authors: | Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J. | Deposit date: | 1992-03-14 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes To be Published
|
|
1DR1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dr1 by Molmil](/molmil-images/mine/1dr1) | 2.2 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADP+ AND BIOPTERIN | Descriptor: | 7,8-DIHYDROBIOPTERIN, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ... | Authors: | Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J. | Deposit date: | 1992-03-14 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin. Biochemistry, 31, 1992
|
|
6VNW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vnw by Molmil](/molmil-images/mine/6vnw) | Cryo-EM structure of apo-BBSome | Descriptor: | BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, Bardet-Biedl syndrome 2 protein homolog, ... | Authors: | Yang, S, Walz, T, Nachury, M, Chou, H. | Deposit date: | 2020-01-29 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes. Elife, 9, 2020
|
|
3F11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f11 by Molmil](/molmil-images/mine/3f11) | Structure of futa1 with iron(III) | Descriptor: | 1,2-ETHANEDIOL, FE (III) ION, Iron transport protein, ... | Authors: | Koropatkin, N.M, Randich, A.M, Bhattachryya-Pakrasi, M, Pakrasi, H.B, Smith, T.J. | Deposit date: | 2008-10-27 | Release date: | 2008-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of the iron-binding protein, FutA1, from Synechocystis 6803 J.Biol.Chem., 282, 2007
|
|
2BKA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bka by Molmil](/molmil-images/mine/2bka) | CC3(TIP30)Crystal Structure | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | El Omari, K, Bird, L.E, Nichols, C.E, Ren, J, Stammers, D.K. | Deposit date: | 2005-02-14 | Release date: | 2005-02-21 | Last modified: | 2016-12-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Cc3 (Tip30): Implications for its Role as a Tumor Suppressor J.Biol.Chem., 280, 2005
|
|
8FTD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ftd by Molmil](/molmil-images/mine/8ftd) | Structure of Escherichia coli CedA in complex with transcription initiation complex | Descriptor: | CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ... | Authors: | Liu, M, Vassyliev, N, Nudler, E. | Deposit date: | 2023-01-11 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | General transcription factor from Escherichia coli with a distinct mechanism of action. Nat.Struct.Mol.Biol., 31, 2024
|
|
3F5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f5e by Molmil](/molmil-images/mine/3f5e) | Crystal structure of Toxoplasma gondii micronemal protein 1 bound to 2'F-3'SiaLacNAc1-3 | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Garnett, J.A, Liu, Y, Feizi, T, Matthews, S.J. | Deposit date: | 2008-11-03 | Release date: | 2009-07-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii. Protein Sci., 18, 2009
|
|
6VOA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6voa by Molmil](/molmil-images/mine/6voa) | Cryo-EM structure of the BBSome-ARL6 complex | Descriptor: | ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ... | Authors: | Yang, S, Walz, T, Nachury, M.V. | Deposit date: | 2020-01-30 | Release date: | 2020-06-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes. Elife, 9, 2020
|
|
1DR7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dr7 by Molmil](/molmil-images/mine/1dr7) | CRYSTAL STRUCTURES OF ORGANOMERCURIAL-ACTIVATED CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXES | Descriptor: | CALCIUM ION, DIHYDROFOLATE REDUCTASE, MERCURIBENZOIC ACID, ... | Authors: | Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J. | Deposit date: | 1992-03-14 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes To be Published
|
|
7OQB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oqb by Molmil](/molmil-images/mine/7oqb) | The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | Descriptor: | ACT1 pre-mRNA (delta-BS-A), Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing ATP-dependent RNA helicase PRP5, ... | Authors: | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | Deposit date: | 2021-06-03 | Release date: | 2021-08-11 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature, 596, 2021
|
|
7OQE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oqe by Molmil](/molmil-images/mine/7oqe) | Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A), Cold sensitive U2 snRNA suppressor 1, ... | Authors: | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | Deposit date: | 2021-06-03 | Release date: | 2021-08-11 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature, 596, 2021
|
|
7OQC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oqc by Molmil](/molmil-images/mine/7oqc) | The U1 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A), Pre-mRNA-processing factor 39, ... | Authors: | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | Deposit date: | 2021-06-03 | Release date: | 2021-08-11 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature, 596, 2021
|
|
4WZA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wza by Molmil](/molmil-images/mine/4wza) | Asymmetric Nucleotide Binding in the Nitrogenase Complex | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, ... | Authors: | Tezcan, F.A, Kaiser, J.T, Howard, J.B, Rees, D.C. | Deposit date: | 2014-11-19 | Release date: | 2014-12-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8995 Å) | Cite: | Structural evidence for asymmetrical nucleotide interactions in nitrogenase. J.Am.Chem.Soc., 137, 2015
|
|
2E21
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e21 by Molmil](/molmil-images/mine/2e21) | Crystal structure of TilS in a complex with AMPPNP from Aquifex aeolicus. | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, tRNA(Ile)-lysidine synthase | Authors: | Kuratani, M, Yoshikawa, Y, Sekine, S, Ishii, T, Shibata, R, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-11-06 | Release date: | 2007-11-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of the initial binding of tRNA(Ile) lysidine synthetase TilS with ATP and L-lysine To be Published
|
|
7OZN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ozn by Molmil](/molmil-images/mine/7ozn) | RNA Polymerase II dimer (Class 1) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Dienemann, C, Cramer, P. | Deposit date: | 2021-06-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
|
|
7OOP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oop by Molmil](/molmil-images/mine/7oop) | Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | Descriptor: | DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... | Authors: | Kokic, G, Cramer, P. | Deposit date: | 2021-05-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
|
|
7OZP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ozp by Molmil](/molmil-images/mine/7ozp) | RNA Polymerase II dimer (Class 3) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Dienemann, C, Cramer, P. | Deposit date: | 2021-06-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
|
|
7OZO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ozo by Molmil](/molmil-images/mine/7ozo) | RNA Polymerase II dimer (Class 2) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Dienemann, C, Cramer, P. | Deposit date: | 2021-06-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
|
|
7OO3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oo3 by Molmil](/molmil-images/mine/7oo3) | Pol II-CSB-CSA-DDB1-UVSSA (Structure1) | Descriptor: | CSB element, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... | Authors: | Kokic, G, Cramer, P. | Deposit date: | 2021-05-26 | Release date: | 2021-10-06 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
|
|