Crystal structure of Toxoplasma gondii micronemal protein 1 bound to 2'F-3'SiaLacNAc1-3

Summary for 3F5E

Related2JH1 2JHD 2JH7 3F53 3F5A
DescriptorMicronemal protein 1, N-acetyl-alpha-neuraminic acid-(2-3)-2-deoxy-2-fluoro-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (6 entities in total)
Functional Keywordscellular adhesion, micronemal protein 1, toxoplasma gondii, carbohydrate, fluorine, cell adhesion, cytoplasmic vesicle, lectin, virulence
Biological sourceToxoplasma gondii
Cellular locationCytoplasmic vesicle, secretory vesicle, microneme  O00834
Total number of polymer chains1
Total molecular weight28910.88
Garnett, J.A.,Liu, Y.,Feizi, T.,Matthews, S.J. (deposition date: 2008-11-03, release date: 2009-07-28, Last modification date: 2020-07-29)
Primary citation
Garnett, J.A.,Liu, Y.,Leon, E.,Allman, S.A.,Friedrich, N.,Saouros, S.,Curry, S.,Soldati-Favre, D.,Davis, B.G.,Feizi, T.,Matthews, S.
Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.
Protein Sci., 18:1935-1947, 2009
PubMed: 19593815 (PDB entries with the same primary citation)
DOI: 10.1002/pro.204
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21340 2.1% 4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21