7EXP
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![BU of 7exp by Molmil](/molmil-images/mine/7exp) | Crystal structure of zebrafish TRAP1 with AMPPNP and MitoQ | Descriptor: | 2,3-dimethoxy-5-methyl-6-[10-(triphenyl-$l^{5}-phosphanyl)decyl]cyclohexa-2,5-diene-1,4-dione, COBALT (II) ION, MAGNESIUM ION, ... | Authors: | Lee, H, Yoon, N.G, Kang, B.H, Lee, C. | Deposit date: | 2021-05-28 | Release date: | 2022-01-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.297 Å) | Cite: | Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site. J.Am.Chem.Soc., 143, 2021
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4CT1
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![BU of 4ct1 by Molmil](/molmil-images/mine/4ct1) | Human PDK1-PKCzeta Kinase Chimera in Complex with Allosteric Compound PS315 Bound to the PIF-Pocket | Descriptor: | (2Z)-3-(biphenyl-4-yl)-5-(4-chlorophenyl)pent-2-enoic acid, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Schulze, J.O, Zhang, H, Lopez-Garcia, L.A, Biondi, R.M. | Deposit date: | 2014-03-11 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular Mechanism of Regulation of the Atypical Protein Kinase C by N-Terminal Domains and an Allosteric Small Compound. Chem.Biol., 21, 2014
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7LUL
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![BU of 7lul by Molmil](/molmil-images/mine/7lul) | Structure of the MM2 Erbin PDZ variant in complex with a high-affinity peptide | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2021-02-22 | Release date: | 2021-07-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021
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7LC2
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![BU of 7lc2 by Molmil](/molmil-images/mine/7lc2) | |
7LC1
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![BU of 7lc1 by Molmil](/molmil-images/mine/7lc1) | |
2CV5
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![BU of 2cv5 by Molmil](/molmil-images/mine/2cv5) | Crystal structure of human nucleosome core particle | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A.a, ... | Authors: | Tsunaka, Y, Kajimura, N, Tate, S, Morikawa, K. | Deposit date: | 2005-05-31 | Release date: | 2005-06-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Alteration of the nucleosomal DNA path in the crystal structure of a human nucleosome core particle Nucleic Acids Res., 33, 2005
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7F6W
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![BU of 7f6w by Molmil](/molmil-images/mine/7f6w) | Crystal structure of Saccharomyces cerevisiae lysyl-tRNA Synthetase | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Lysine--tRNA ligase | Authors: | Wu, S, Li, P, Hei, Z, Zheng, L, Wang, J, Fang, P. | Deposit date: | 2021-06-26 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.607 Å) | Cite: | Human lysyl-tRNA synthetase evolves a dynamic structure that can be stabilized by forming complex. Cell.Mol.Life Sci., 79, 2022
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4CS5
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![BU of 4cs5 by Molmil](/molmil-images/mine/4cs5) | Crystal Structure of PCNA from Litopenaeus vannamei | Descriptor: | PROLIFERATING CELL NUCLEAR ANTIGEN | Authors: | Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R. | Deposit date: | 2014-03-04 | Release date: | 2014-04-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box. Plos One, 9, 2014
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1UZC
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![BU of 1uzc by Molmil](/molmil-images/mine/1uzc) | THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11 | Descriptor: | HYPOTHETICAL PROTEIN FLJ21157 | Authors: | Allen, M.D, Jemth, P, Friedler, A, Schon, O, Bycroft, M. | Deposit date: | 2004-03-09 | Release date: | 2004-04-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Structure of an Ff Domain from Human Hypa/Fbp11. J.Mol.Biol., 323, 2002
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4D26
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![BU of 4d26 by Molmil](/molmil-images/mine/4d26) | Crystal structure of the Bombyx mori Vasa helicase (E339Q) in complex with RNA,ADP and Pi | Descriptor: | 5'-R(*UP*GP*AP*CP*AP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, BMVLG PROTEIN, ... | Authors: | Spinelli, P, Pillai, R.S, Kadlec, J, Cusack, S. | Deposit date: | 2014-05-07 | Release date: | 2014-06-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | RNA Clamping by Vasa Assembles a Pirna Amplifier Complex on Transposon Transcripts. Cell(Cambridge,Mass.), 157, 2014
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2EVA
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![BU of 2eva by Molmil](/molmil-images/mine/2eva) | Structural Basis for the Interaction of TAK1 Kinase with its Activating Protein TAB1 | Descriptor: | ADENOSINE, TAK1 kinase - TAB1 chimera fusion protein | Authors: | Brown, K, Vial, S.C, Dedi, N, Long, J.M, Dunster, N.J, Cheetham, G.M. | Deposit date: | 2005-10-31 | Release date: | 2006-05-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the interaction of TAK1 kinase with its activating protein TAB1 J.Mol.Biol., 354, 2005
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4ZXO
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![BU of 4zxo by Molmil](/molmil-images/mine/4zxo) | The structure of a GH26 beta-mannanase from Bacteroides ovatus, BoMan26A. | Descriptor: | Glycosyl hydrolase family 26, PHOSPHATE ION, POTASSIUM ION | Authors: | Bagenholm, V, Aurelius, O, Logan, D.T, Bouraoui, H, Stalbrand, H. | Deposit date: | 2015-05-20 | Release date: | 2016-06-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Galactomannan Catabolism Conferred by a Polysaccharide Utilization Locus of Bacteroides ovatus: ENZYME SYNERGY AND CRYSTAL STRUCTURE OF A beta-MANNANASE. J. Biol. Chem., 292, 2017
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4EWI
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![BU of 4ewi by Molmil](/molmil-images/mine/4ewi) | Crystal structure of the NLRP4 Pyrin domain | Descriptor: | CHLORIDE ION, NACHT, LRR and PYD domains-containing protein 4, ... | Authors: | Eibl, C, Hessenberger, M, Puehringer, S, Page, R, Diederichs, K, Peti, W. | Deposit date: | 2012-04-27 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural and Functional Analysis of the NLRP4 Pyrin Domain. Biochemistry, 51, 2012
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4EWQ
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![BU of 4ewq by Molmil](/molmil-images/mine/4ewq) | Human p38 alpha MAPK in complex with a pyridazine based inhibitor | Descriptor: | 3-phenyl-4-(pyridin-4-yl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine, 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, ACETATE ION, ... | Authors: | Grum-Tokars, V, Minasov, G, Roy, S, Schavocky, J, Winsor, J, Watterson, D.M, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-04-27 | Release date: | 2012-06-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Selective and Brain Penetrant p38 alpha MAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction. J.Med.Chem., 62, 2019
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4E6C
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![BU of 4e6c by Molmil](/molmil-images/mine/4e6c) | p38a-perifosine Complex | Descriptor: | (1,1-dimethylpiperidin-1-ium-4-yl) octadecyl hydrogen phosphate, Mitogen-activated protein kinase 14 | Authors: | Livnah, O, Tzarum, N, Eisenberg-Domovich, Y. | Deposit date: | 2012-03-15 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch. J.Mol.Biol., 424, 2012
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4E8A
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![BU of 4e8a by Molmil](/molmil-images/mine/4e8a) | The crystal structure of p38a MAP kinase in complex with PIA24 | Descriptor: | (1R,2S,3R,4S,6S)-6-(cyclohexylmethoxy)-2,3,4-trihydroxycyclohexyl (2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen (S)-phosphate, Mitogen-activated protein kinase 14 | Authors: | Livnah, O, Tzarum, N, Eisenberg-Domovich, Y. | Deposit date: | 2012-03-20 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch. J.Mol.Biol., 424, 2012
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7EVO
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![BU of 7evo by Molmil](/molmil-images/mine/7evo) | The cryo-EM structure of the human 17S U2 snRNP | Descriptor: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ... | Authors: | Zhang, X, Zhan, X, Shi, Y. | Deposit date: | 2021-05-21 | Release date: | 2022-08-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
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4EH9
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![BU of 4eh9 by Molmil](/molmil-images/mine/4eh9) | Human p38 MAP kinase in complex with NP-F11 and RL87 | Descriptor: | (1R,5S)-3-[4-(trifluoromethyl)benzoyl]-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one, Mitogen-activated protein kinase 14, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine | Authors: | Over, B, Gruetter, C, Waldmann, H, Rauh, D. | Deposit date: | 2012-04-02 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem, 5, 2012
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4EWV
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![BU of 4ewv by Molmil](/molmil-images/mine/4ewv) | Crystal structure of GH3.12 in complex with AMPCPP | Descriptor: | 4-substituted benzoates-glutamate ligase GH3.12, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION | Authors: | Zubieta, C, Nanao, M, Jez, J. | Deposit date: | 2012-04-28 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.897 Å) | Cite: | Structural basis for prereceptor modulation of plant hormones by GH3 proteins. Science, 336, 2012
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4E5A
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2DMV
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![BU of 2dmv by Molmil](/molmil-images/mine/2dmv) | Solution structure of the second ww domain of Itchy homolog E3 ubiquitin protein ligase (Itch) | Descriptor: | Itchy homolog E3 ubiquitin protein ligase | Authors: | Ohnishi, S, Paakkonen, K, Tochio, N, Tomizawa, T, Koshiba, S, Inoue, M, Guntert, P, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-24 | Release date: | 2006-10-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the second ww domain of Itchy homolog E3 ubiquitin protein ligase (Itch) To be Published
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2DO4
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![BU of 2do4 by Molmil](/molmil-images/mine/2do4) | Solution structure of the RNA binding domain of squamous cell carcinoma antigen recognized by T cells 3 | Descriptor: | Squamous cell carcinoma antigen recognized by T-cells 3 | Authors: | Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-27 | Release date: | 2007-04-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RNA binding domain of squamous cell carcinoma antigen recognized by T cells 3 To be Published
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2OP7
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![BU of 2op7 by Molmil](/molmil-images/mine/2op7) | WW4 | Descriptor: | NEDD4-like E3 ubiquitin-protein ligase WWP1 | Authors: | Qin, H.N, Li, M.F, Pu, H, Sankaran, S, Ahmed, S, Song, J.X. | Deposit date: | 2007-01-27 | Release date: | 2007-12-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR structure of the forth WW domain of WWP1 To be Published
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4EET
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![BU of 4eet by Molmil](/molmil-images/mine/4eet) | Crystal structure of iLOV | Descriptor: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | Authors: | Hitomi, K, Christie, J.M, Arvai, A.S, Hartfield, K.A, Pratt, A.J, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2012-03-28 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability. J.Biol.Chem., 287, 2012
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4EHV
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![BU of 4ehv by Molmil](/molmil-images/mine/4ehv) | Human p38 MAP kinase in complex with NP-F10 and RL87 | Descriptor: | (1R,5S)-3-(4-chlorobenzoyl)-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one, Mitogen-activated protein kinase 14, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine | Authors: | Over, B, Gruetter, C, Waldmann, H, Rauh, D. | Deposit date: | 2012-04-04 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem, 5, 2012
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