4EWI
Crystal structure of the NLRP4 Pyrin domain
Summary for 4EWI
Entry DOI | 10.2210/pdb4ewi/pdb |
Descriptor | NACHT, LRR and PYD domains-containing protein 4, CHLORIDE ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | nlr proteins, death domain, pyrin domain, nlrp4, asc, innate immune system, inflammasome, apoptosis, protein-protein interaction, signaling protein, protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 27785.20 |
Authors | Eibl, C.,Hessenberger, M.,Puehringer, S.,Page, R.,Diederichs, K.,Peti, W. (deposition date: 2012-04-27, release date: 2012-09-05, Last modification date: 2024-02-28) |
Primary citation | Eibl, C.,Grigoriu, S.,Hessenberger, M.,Wenger, J.,Puehringer, S.,Pinheiro, A.S.,Wagner, R.N.,Proell, M.,Reed, J.C.,Page, R.,Diederichs, K.,Peti, W. Structural and Functional Analysis of the NLRP4 Pyrin Domain. Biochemistry, 51:7330-7341, 2012 Cited by PubMed: 22928810DOI: 10.1021/bi3007059 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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