4EWI
Crystal structure of the NLRP4 Pyrin domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NACHT, LRR and PYD domains-containing protein 4 | polymer | 113 | 13809.1 | 2 | UniProt (Q96MN2) Pfam (PF02758) | Homo sapiens (human) | Cancer/testis antigen 58, CT58, PAAD and NACHT-containing protein 2, PYRIN and NACHT-containing protein 2, PYRIN-containing APAF1-like protein 4, Ribonuclease inhibitor 2 |
| 2 | C, D (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | E (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 110 (UniProt: Q96MN2)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Glu 111 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27618.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 167.0 | |
| All* | Total formula weight | 27785.2 |
