PDB: 10253 resultsInfo pagesStatus searchChemie searchBIRD

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3JSB	Crystal structure of the N-terminal domain of the Lymphocytic Choriomeningitis Virus L protein Descriptor: RNA-directed RNA polymerase Authors: Morin, B, Jamal, S, Ferron, F.P, Coutard, B, Bricogne, G, Canard, B, Vonrhein, C, Marseilles Structural Genomics Program @ AFMB (MSGP) Deposit date: 2009-09-10 Release date: 2010-09-15 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.13 Å) Cite: The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription Plos Pathog., 6, 2010
4L87	Crystal structure of the human seryl-tRNA synthetase in complex with Ser-SA at 2.9 Angstrom resolution Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Xu, X, Yang, X.-L. Deposit date: 2013-06-16 Release date: 2013-10-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.897 Å) Cite: Crystal Structure of Human Seryl-tRNA Synthetase and Ser-SA Complex Reveals a Molecular Lever Specific to Higher Eukaryotes. Structure, 21, 2013
7QDY	RNA-bound human SKI complex Descriptor: Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... Authors: Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. Deposit date: 2021-12-01 Release date: 2022-02-09 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
8B9I	Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ... Authors: Jagtap, P.K.A, Hennig, J. Deposit date: 2022-10-06 Release date: 2023-10-18 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8B9G	Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ... Authors: Jagtap, P.K.A, Hennig, J. Deposit date: 2022-10-06 Release date: 2023-10-18 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
4PTF	Ternary crystal structure of yeast DNA polymerase epsilon with template G Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', ... Authors: Jain, R, Rajashankar, K.R, Buku, A, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. Deposit date: 2014-03-10 Release date: 2014-04-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.809 Å) Cite: Crystal Structure of Yeast DNA Polymerase epsilon Catalytic Domain. Plos One, 9, 2014
2M23	NMR solution structure of the d3'-hairpin of the group II intron Sc.ai5gamma including EBS1 bound to IBS1 Descriptor: RNA (29-MER), RNA_(5'-R(*CP*AP*GP*UP*GP*UP*C)-3')_ Authors: Kruschel, D, Skilandat, M, Sigel, R.K.O. Deposit date: 2012-12-12 Release date: 2013-12-18 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: NMR structure of the 5' splice site in the group IIB intron Sc.ai5 gamma--conformational requirements for exon-intron recognition. Rna, 20, 2014
2M24	NMR solution structure of the d3'-hairpin including the exon binding site 1 (EBS1) of the group II intron Sc.ai5gamma Descriptor: RNA (29-MER) Authors: Kruschel, D, Skilandat, M, Sigel, R.K.O. Deposit date: 2012-12-12 Release date: 2013-12-18 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: NMR structure of the 5' splice site in the group IIB intron Sc.ai5 gamma--conformational requirements for exon-intron recognition. Rna, 20, 2014
9EAL	SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State II - precleavage) Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (Non-target strand), DNA (Target Strand), ... Authors: Kiernan, K.A, Taylor, D.W. Deposit date: 2024-11-11 Release date: 2025-07-09 Method: ELECTRON MICROSCOPY (2.83 Å) Cite: Visualization of a multi-turnover Cas9 after product release. Nat Commun, 16, 2025
8P4F	Structural insights into human co-transcriptional capping - structure 6 Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (38-MER), ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-07-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
8P4E	Structural insights into human co-transcriptional capping - structure 5 Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (26-MER), DNA (35-MER), ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-07-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
8P4C	Structural insights into human co-transcriptional capping - structure 3 Descriptor: DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
8P4D	Structural insights into human co-transcriptional capping - structure 4 Descriptor: DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
8P4B	Structural insights into human co-transcriptional capping - structure 2 Descriptor: DNA (35-MER), DNA (5'-D(P*AP*GP*CP*GP*GP*CP*GP*GP*AP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*AP*GP*CP*TP*G)-3'), DNA-directed RNA polymerase II subunit E, ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
8P4A	Structural insights into human co-transcriptional capping - structure 1 Descriptor: DNA (29-MER), DNA (38-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-08-16 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
6CCE	Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Kanglemycin A Descriptor: 1,2-ETHANEDIOL, DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Lilic, M, Darst, S.A, Campbell, E.A. Deposit date: 2018-02-07 Release date: 2018-08-15 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
5D4E	Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP Descriptor: CYTIDINE-5'-MONOPHOSPHATE, DEPHOSPHO COENZYME A, DIPHOSPHATE, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-08-07 Release date: 2016-07-06 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (3.08 Å) Cite: The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
6PB4	The E. coli class-II CAP-dependent transcription activation complex with de novo RNA transcript at the state 2 Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W. Deposit date: 2019-06-13 Release date: 2020-03-18 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.35 Å) Cite: Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PB5	The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W. Deposit date: 2019-06-13 Release date: 2020-03-18 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.52 Å) Cite: Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
7ABG	Human pre-Bact-1 spliceosome Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... Authors: Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. Deposit date: 2020-09-07 Release date: 2020-12-23 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (7.8 Å) Cite: Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
8PH9	E. coli RNA polymerase paused at ops site (non-complementary scaffold) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. Deposit date: 2023-06-19 Release date: 2024-04-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
8PDY	E. coli RNA polymerase paused at ops site Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. Deposit date: 2023-06-13 Release date: 2024-04-24 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
9F37	Replication-like initiation state of influenza polymerase with GTP and CTP at respectively the -1 and +1 positions (strain A/little yellow-shouldered bat/Guatemala/060/2010/H17N10) Descriptor: 3' end of the vRNA promoter, 5' end of the vRNA promoter, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... Authors: Cusack, S, Drncova, P. Deposit date: 2024-04-25 Release date: 2024-09-18 Method: X-RAY DIFFRACTION (1.905 Å) Cite: High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit Biorxiv, 2024
8YFR	Cryo EM structure of Komagataella phaffii Rat1-Rai1 complex bound within the RNAPII cleft Descriptor: 5'-3' exoribonuclease, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... Authors: Murayama, Y, Yanagisawa, T, Ehara, H, Sekine, S. Deposit date: 2024-02-25 Release date: 2024-09-25 Last modified: 2025-06-25 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nat Commun, 15, 2024
8YFQ	Cryo EM structure of Komagataella phaffii RNAPII-Rat1-Rai1 pre-termination complex Descriptor: 5'-3' exoribonuclease, DNA (90-mer), DNA-directed RNA polymerase subunit, ... Authors: Murayama, Y, Yanagisawa, T, Ehara, H, Sekine, S. Deposit date: 2024-02-25 Release date: 2024-09-25 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex. Nat Commun, 15, 2024

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