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6WVL
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BU of 6wvl by Molmil
Low curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Debs, G.E, Cha, M, Huehn, A.R, Sindelar, C.V.
Deposit date:2020-05-06
Release date:2020-05-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy.
Proc.Natl.Acad.Sci.USA, 117, 2020
8BX0
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BU of 8bx0 by Molmil
fragment-linked stabilizer for ERa - 14-3-3 interaction (1074388)
Descriptor: 14-3-3 protein sigma, ERalpha peptide, ~{N}-[3-(5-carbamimidoylthiophen-3-yl)phenyl]-2-(4-methoxyphenoxy)-2-methyl-propanamide
Authors:Visser, E.J, Vandenboorn, E.M.F, Ottmann, C.
Deposit date:2022-12-07
Release date:2023-08-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:From Tethered to Freestanding Stabilizers of 14-3-3 Protein-Protein Interactions through Fragment Linking.
Angew.Chem.Int.Ed.Engl., 62, 2023
6WXD
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BU of 6wxd by Molmil
SARS-CoV-2 Nsp9 RNA-replicase
Descriptor: Non-structural protein 9, SULFATE ION
Authors:Littler, D.R, Gully, B.S, Riboldi-Tunnicliffe, A, Rossjohn, J.
Deposit date:2020-05-10
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9.
Iscience, 23, 2020
4K9R
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BU of 4k9r by Molmil
Spore photoproduct lyase Y98F mutant
Descriptor: IRON/SULFUR CLUSTER, SULFATE ION, Spore photoproduct lyase, ...
Authors:Yang, L, Nelson, R.S, Benjdia, A, Lin, G, Telser, J, Stoll, S, Schlichting, I, Li, L.
Deposit date:2013-04-20
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A radical transfer pathway in spore photoproduct lyase.
Biochemistry, 52, 2013
5AP9
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BU of 5ap9 by Molmil
Controlled lid-opening in Thermomyces lanuginosus lipase - a switch for activity and binding
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Skjold-Joergensen, J, Vind, J, Moroz, O.V, Blagova, E.V, Bhatia, V.K, Svendsen, A, Wilson, K.S, Bjerrum, M.J.
Deposit date:2015-09-15
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Controlled lid-opening in Thermomyces lanuginosus lipase- An engineered switch for studying lipase function.
Biochim. Biophys. Acta, 1865, 2017
6X0V
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BU of 6x0v by Molmil
Structure of MZT2/GCP-NHD and CDK5Rap2 at position 13 of the gamma-TuRC
Descriptor: Centrosome protein Cep215, Gamma-tubulin complex component 2, Mitotic-spindle organizing protein 2A
Authors:Wieczorek, M, Huang, T.-L, Urnavicius, L, Hsia, K.-C, Kapoor, T.M.
Deposit date:2020-05-17
Release date:2020-07-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:MZT Proteins Form Multi-Faceted Structural Modules in the gamma-Tubulin Ring Complex.
Cell Rep, 31, 2020
2DH3
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BU of 2dh3 by Molmil
Crystal Structure of human ED-4F2hc
Descriptor: 4F2 cell-surface antigen heavy chain, ZINC ION
Authors:Fort, J, Fita, I, Palacin, M.
Deposit date:2006-03-21
Release date:2007-03-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane.
J.Biol.Chem., 282, 2007
4ZT1
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BU of 4zt1 by Molmil
Crystal structure of human E-Cadherin (residues 3-213) in x-dimer conformation
Descriptor: CALCIUM ION, Cadherin-1
Authors:Nardone, V, Lucarelli, A.P, Dalle Vedove, A, Parisini, E.
Deposit date:2015-05-14
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Competitive Inhibitor of Cadherin Homophilic Interaction.
J.Med.Chem., 59, 2016
4ZYR
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BU of 4zyr by Molmil
Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG)
Descriptor: 4-nitrophenyl alpha-D-galactopyranoside, Lactose permease, nonyl beta-D-glucopyranoside
Authors:Kumar, H, Finer-Moore, J.S, Kaback, H.R, Stroud, R.M.
Deposit date:2015-05-22
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.312 Å)
Cite:Structure of LacY with an alpha-substituted galactoside: Connecting the binding site to the protonation site.
Proc.Natl.Acad.Sci.USA, 112, 2015
8B9C
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BU of 8b9c by Molmil
S. cerevisiae pol alpha - replisome complex
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9B
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BU of 8b9b by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
4K3M
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BU of 4k3m by Molmil
E.coli sliding clamp in complex with AcALDLF peptide
Descriptor: ALDLF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-04-11
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp
J.Med.Chem., 56, 2013
6WJB
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BU of 6wjb by Molmil
UDP-GlcNAc C4-epimerase from Pseudomonas protegens in complex with NAD and UDP-GlcNAc
Descriptor: NAD-dependent epimerase/dehydratase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Marmont, L.S, Pfoh, R, Robinson, H, Howell, P.L.
Deposit date:2020-04-13
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation.
J.Biol.Chem., 295, 2020
6WJJ
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BU of 6wjj by Molmil
Anthrax octamer prechannel bound to full-length lethal factor
Descriptor: CALCIUM ION, Lethal factor, Protective antigen, ...
Authors:Zhou, K, Hardenbrook, N.J, Liu, S, Cui, Y.X, Krantz, B.A, Zhou, Z.H.
Deposit date:2020-04-13
Release date:2020-12-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors.
Structure, 28, 2020
8B9A
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BU of 8b9a by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
3I7F
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BU of 3i7f by Molmil
Aspartyl tRNA synthetase from Entamoeba histolytica
Descriptor: Aspartyl-tRNA synthetase
Authors:Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-07-08
Release date:2009-07-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica.
Mol.Biochem.Parasitol., 169, 2010
4CXI
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BU of 4cxi by Molmil
BTB domain of KEAP1
Descriptor: KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
Authors:Cleasby, A, Yon, J, Day, P.J, Richardson, C, Tickle, I.J, Williams, P.A, Callahan, J.F, Carr, R, Concha, N, Kerns, J.K, Qi, H, Sweitzer, T, Ward, P, Davies, T.G.
Deposit date:2014-04-07
Release date:2014-06-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of the Btb Domain of Keap1 and its Interaction with the Triterpenoid Antagonist Cddo.
Plos One, 9, 2014
4ZWR
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BU of 4zwr by Molmil
Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type II
Descriptor: Recombination protein uvsY
Authors:Gajewski, S, White, S.W.
Deposit date:2015-05-19
Release date:2016-03-02
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (3.3857 Å)
Cite:Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
8BQS
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BU of 8bqs by Molmil
Cryo-EM structure of the I-II-III2-IV2 respiratory supercomplex from Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Baradaran, R, Amunts, A.
Deposit date:2022-11-21
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
To Be Published
5A9E
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BU of 5a9e by Molmil
Cryo-electron tomography and subtomogram averaging of Rous-Sarcoma- Virus deltaMBD virus-like particles
Descriptor: DELTAMBD GAG PROTEIN
Authors:Schur, F.K.M, Dick, R.A, Hagen, W.J.H, Vogt, V.M, Briggs, J.A.G.
Deposit date:2015-07-21
Release date:2015-08-12
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:The Structure of Immature-Like Rous Sarcoma Virus Gag Particles Reveals a Structural Role for the P10 Domain in Assembly.
J.Virol., 89, 2015
8B69
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BU of 8b69 by Molmil
Heterotetramer of K-Ras4B(G12V) and Rgl2(RBD)
Descriptor: Isoform 2B of GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Tariq, M, Fairall, L, Romartinez-Alonso, B, Dominguez, C, Schwabe, J.W.R, Tanaka, K.
Deposit date:2022-09-26
Release date:2023-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Structural insights into the complex of oncogenic KRas4B G12V and Rgl2, a RalA/B activator.
Life Sci Alliance, 7, 2024
4ZRY
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BU of 4zry by Molmil
Crystal structure of the heterocomplex between coil 2B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10)
Descriptor: Keratin, type I cytoskeletal 10, type II cytoskeletal 1
Authors:Bunick, C.G, Steitz, T.A.
Deposit date:2015-05-12
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.30012512 Å)
Cite:The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease.
J. Invest. Dermatol., 137, 2017
2ZWN
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BU of 2zwn by Molmil
Crystal structure of the novel two-domain type laccase from a metagenome
Descriptor: CHLORIDE ION, COPPER (II) ION, CU-O-CU LINKAGE, ...
Authors:Komori, H, Miyazaki, K, Higuchi, Y.
Deposit date:2008-12-17
Release date:2009-04-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray structure of a two-domain type laccase: a missing link in the evolution of multi-copper proteins
Febs Lett., 583, 2009
2IEW
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BU of 2iew by Molmil
Crystal structure of Inositol Phosphate Multikinase Ipk2 from S. cerevisiae
Descriptor: CALCIUM ION, Inositol polyphosphate multikinase
Authors:Holmes, W, Jogl, G.
Deposit date:2006-09-19
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity.
J.Biol.Chem., 281, 2006
6WLC
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BU of 6wlc by Molmil
Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with Uridine-5'-Monophosphate
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ...
Authors:Kim, Y, Maltseva, N, Jedrzejczak, R, Endres, M, Chang, C, Godzik, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-19
Release date:2020-04-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2.
Commun Biol, 4, 2021

223790

数据于2024-08-14公开中

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