4ZRY

Crystal structure of the heterocomplex between coil 2B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10)

Summary for 4ZRY

Entry DOI	10.2210/pdb4zry/pdb
Descriptor	Keratin, type I cytoskeletal 10, Keratin, type II cytoskeletal 1 (2 entities in total)
Functional Keywords	keratin, intermediate filament, coiled-coil, skin, protein-protein complex, epidermis, helix, protein fibril
Biological source	Homo sapiens (Human) More
Cellular location	Cell membrane : P04264
Total number of polymer chains	2
Total formula weight	28254.32
Authors	Bunick, C.G.,Steitz, T.A. (deposition date: 2015-05-12, release date: 2016-05-18, Last modification date: 2023-09-27)
Primary citation	Bunick, C.G.,Milstone, L.M. The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease. J. Invest. Dermatol., 137:142-150, 2017 Cited by PubMed: 27595935 DOI: 10.1016/j.jid.2016.08.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.30012502044 Å)

Structure validation