PDB: 222624 resultsInfo pagesStatus searchChemie searchBIRD

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8XAT	Crystal structure of AtARR1(RD-DBD) Descriptor: Two-component response regulator ARR1 Authors: Li, J.X, Zhou, C.M, Zhang, P, Wang, J.W. Deposit date: 2023-12-05 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.205 Å) Cite: The structure of B-ARR reveals the molecular basis of transcriptional activation by cytokinin. Proc.Natl.Acad.Sci.USA, 121, 2024
8XAS	Crystal structure of AtARR1-DBD in complex with a DNA fragment Descriptor: DNA (50-MER), Two-component response regulator ARR1 Authors: Li, J.X, Zhou, C.M, zhang, P, Wang, J.W. Deposit date: 2023-12-05 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.346 Å) Cite: The structure of B-ARR reveals the molecular basis of transcriptional activation by cytokinin. Proc.Natl.Acad.Sci.USA, 121, 2024
8XAR	Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with SAM and Compound 54 Descriptor: 1,2-ETHANEDIOL, 7-chloranyl-2-ethyl-5-pyridin-3-yl-pyrazolo[3,4-c]quinolin-4-one, CHLORIDE ION, ... Authors: Zheng, J.Y, Zhang, G.P, Li, J.J, Tong, S.L. Deposit date: 2023-12-05 Release date: 2024-06-26 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy. J.Med.Chem., 67, 2024
8XAM	Co-crystal structure of compound 7 in complex with MAT2A Descriptor: 2-[3-[7-chloranyl-4-(dimethylamino)-2-oxidanylidene-quinazolin-1-yl]phenoxy]-~{N}-[3-[7-chloranyl-4-(dimethylamino)-2-oxidanylidene-quinazolin-1-yl]phenyl]ethanamide, S-ADENOSYLMETHIONINE, S-adenosylmethionine synthase isoform type-2 Authors: Gao, F, Ding, X. Deposit date: 2023-12-04 Release date: 2024-02-28 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Discovery of novel MAT2A inhibitors by an allosteric site-compatible fragment growing approach. Bioorg.Med.Chem., 100, 2024
8XAJ	Cryo-EM structure of OSCA1.2-liposome-inside-in open state Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Calcium permeable stress-gated cation channel 1 Authors: Zhang, Y, Han, Y. Deposit date: 2023-12-04 Release date: 2024-04-10 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.29 Å) Cite: Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628, 2024
8XAI	Crystal structure of Protease CPAVM1 in Bacillus subtilis LjM2 Descriptor: Lipoprotein Authors: Zhang, J, Wang, C.Y. Deposit date: 2023-12-04 Release date: 2024-06-19 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Anti-influenza activity of CPAVM1 protease secreted by Bacillus subtilis LjM2. Antiviral Res., 228, 2024
8XAB	Crystal structure of Ubl1 domain of nonstructural protein 3 of SARS-CoV-2 Descriptor: GLYCEROL, Papain-like protease nsp3 Authors: Li, Y, Ke, Z. Deposit date: 2023-12-03 Release date: 2023-12-20 Method: X-RAY DIFFRACTION (1.49 Å) Cite: N-terminus of SARS-CoV-2 Nsp3 Interrupts RNA-driven Phase Separation of N Protein by Displacing RNA To Be Published
8XA9	Human MGME1 in complex with 5'-overhang DNA Descriptor: CALCIUM ION, DNA (11-MER), DNA (18-MER), ... Authors: Wu, C.C, Mao, E.Y.C. Deposit date: 2023-12-03 Release date: 2024-03-20 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Structural basis of how MGME1 processes DNA 5' ends to maintain mitochondrial genome integrity. Nucleic Acids Res., 52, 2024
8X9H	Crystal structure of CO dehydrogenase mutant (F41C) Descriptor: Carbon monoxide dehydrogenase 2, FE (III) ION, FE(4)-NI(1)-S(4) CLUSTER, ... Authors: Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y. Deposit date: 2023-11-30 Release date: 2024-04-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity. Nat Commun, 15, 2024
8X9G	Crystal structure of CO dehydrogenase mutant in complex with BV Descriptor: 1-(phenylmethyl)-4-[1-(phenylmethyl)pyridin-1-ium-4-yl]pyridin-1-ium, Carbon monoxide dehydrogenase 2, FE(4)-NI(1)-S(4) CLUSTER, ... Authors: Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y. Deposit date: 2023-11-30 Release date: 2024-04-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity. Nat Commun, 15, 2024
8X9F	Crystal structure of CO dehydrogenase mutant in complex with EV Descriptor: 1,2-ETHANEDIOL, 1-ethyl-4-(1-ethylpyridin-1-ium-4-yl)pyridin-1-ium, Carbon monoxide dehydrogenase 2, ... Authors: Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y. Deposit date: 2023-11-30 Release date: 2024-04-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity. Nat Commun, 15, 2024
8X9E	Crystal structure of CO dehydrogenase mutant with increased affinity for electron mediators in low PEG concentration Descriptor: 1,2-ETHANEDIOL, Carbon monoxide dehydrogenase 2, FE (III) ION, ... Authors: Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y. Deposit date: 2023-11-30 Release date: 2024-04-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity. Nat Commun, 15, 2024
8X9D	Crystal structure of CO dehydrogenase mutant with increased affinity for electron mediators in high PEG concentration Descriptor: Carbon monoxide dehydrogenase 2, FE (III) ION, FE(4)-NI(1)-S(4) CLUSTER, ... Authors: Lee, H.H, Heo, Y, Yoon, H.J, Kim, S.M, Kong, S.Y. Deposit date: 2023-11-30 Release date: 2024-04-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Identifying a key spot for electron mediator-interaction to tailor CO dehydrogenase's affinity. Nat Commun, 15, 2024
8X93	P/Q type calcium channel in complex with omega-Agatoxin IVA Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Yan, N, Li, Z, Cong, Y, Wu, T, Wang, T. Deposit date: 2023-11-29 Release date: 2024-03-20 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.92 Å) Cite: Structural basis for different omega-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell Res., 34, 2024
8X91	P/Q type calcium channel in complex with omega-conotoxin MVIIC Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Yan, N, Li, Z, Cong, Y, Wu, T, Wang, T. Deposit date: 2023-11-29 Release date: 2024-03-20 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.11 Å) Cite: Structural basis for different omega-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell Res., 34, 2024
8X90	P/Q type calcium channel Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE], 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Yan, N, Li, Z, Cong, Y, Wu, T, Wang, T. Deposit date: 2023-11-29 Release date: 2024-03-20 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: Structural basis for different omega-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell Res., 34, 2024
8X8V	Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment Descriptor: Polyhedrin,Myc proto-oncogene protein Authors: Kojima, M, Ueno, T, Abe, S, Hirata, K. Deposit date: 2023-11-29 Release date: 2024-06-05 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (2 Å) Cite: High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
8X8T	NMR structure of p75NTR juxtamembrane domain in complex with RhoGDI N-terminal domain containing a phosphorylation-mimicking S34D mutation Descriptor: Rho GDP-dissociation inhibitor 1, Tumor necrosis factor receptor superfamily member 16 Authors: Lin, Z, Li, Z. Deposit date: 2023-11-28 Release date: 2024-04-03 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: RhoGDI phosphorylation by PKC promotes its interaction with death receptor p75 NTR to gate axon growth and neuron survival. Embo Rep., 25, 2024
8X8S	Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment Descriptor: Polyhedrin,Myc proto-oncogene protein Authors: Kojima, M, Ueno, T, Abe, S, Hirata, K. Deposit date: 2023-11-28 Release date: 2024-06-05 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (2.04 Å) Cite: High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
8X8Q	Structure of enterovirus protease in complex host factor Descriptor: 2A protein (Fragment), Actin-histidine N-methyltransferase, ZINC ION Authors: Gao, X, Cui, S. Deposit date: 2023-11-28 Release date: 2024-05-29 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction. Nat Commun, 15, 2024
8X8P	Phenylethanol rhamnosyltransferase (CmGT3) Descriptor: 1,2-ETHANEDIOL, Phenylethanol rhamnosyltransferase (CmGT3) Authors: Wang, H.T, Wang, Z.L, Ye, M. Deposit date: 2023-11-28 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Structure of Phenylethanol rhamnosyltransferase(CmGT3) To Be Published
8X8N	Cryo-EM structure of the octreotide-bound Somatostatin receptor 5-Gi protein complex Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha, ... Authors: Xu, H.E, You, C, Zhao, L, Li, J. Deposit date: 2023-11-27 Release date: 2024-06-12 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Cryo-EM structure of the octreotide-bound Somatostatin receptor 5-Gi protein complex To Be Published
8X8L	Cryo-EM structure of the cortistatin 17-bound Somatostatin receptor 5-Gi protein complex Descriptor: Cortistatin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Xu, H.E, You, C, Zhao, L, Li, J. Deposit date: 2023-11-27 Release date: 2024-06-12 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Cryo-EM structure of the cortistatin 17-bound Somatostatin receptor 5-Gi protein complex To Be Published
8X8G	Crystal structure of EndoSz mutant D234M, from Streptococcus equi subsp. Zooepidemicus Sz105, in complex with oligosaccharide G2S2-oxazoline Descriptor: 2-METHYL-4,5-DIHYDRO-(1,2-DIDEOXY-ALPHA-D-GLUCOPYRANOSO)[2,1-D]-1,3-OXAZOLE, CALCIUM ION, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, ... Authors: Guan, H.H, Lin, C.C, Hsieh, Y.C, Chen, C.J. Deposit date: 2023-11-27 Release date: 2024-07-03 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Structure-Based High-Efficiency Homogeneous Antibody Platform by Endoglycosidase Sz Provides Insights into Its Transglycosylation Mechanism. Jacs Au, 4, 2024
8X88	The Crystal Structure of TNIK from Biortus. Descriptor: TRAF2 and NCK-interacting protein kinase Authors: Wang, F, Cheng, W, Lv, Z, Meng, Q, Xu, Y. Deposit date: 2023-11-27 Release date: 2023-12-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The Crystal Structure of TNIK from Biortus. To Be Published

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