8X93

P/Q type calcium channel in complex with omega-Agatoxin IVA

Summary for 8X93

• Entry DOI: 10.2210/pdb8x93/pdb
• EMDB information: 38160
• Descriptor: Voltage-dependent L-type calcium channel subunit beta-3, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate, CHOLESTEROL HEMISUCCINATE, ... (12 entities in total)
• Functional Keywords: voltage-gated calcium channel in complex with toxin, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 478564.86

Authors

Yan, N.,Li, Z.,Cong, Y.,Wu, T.,Wang, T. (deposition date: 2023-11-29, release date: 2024-03-20)

• Primary citation: Li, Z.,Cong, Y.,Wu, T.,Wang, T.,Lou, X.,Yang, X.,Yan, N.; Structural basis for different omega-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels.; Cell Res., 2024; PubMed: 38443561; DOI: 10.1038/s41422-024-00940-5

Experimental method

ELECTRON MICROSCOPY (2.92 Å)