8XA9

Human MGME1 in complex with 5'-overhang DNA

Summary for 8XA9

• Entry DOI: 10.2210/pdb8xa9/pdb
• Descriptor: Mitochondrial genome maintenance exonuclease 1, DNA (18-MER), DNA (11-MER), ... (5 entities in total)
• Functional Keywords: exonuclease, hydrolase, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 76072.01

Authors

Wu, C.C.,Mao, E.Y.C. (deposition date: 2023-12-03, release date: 2024-03-20)

• Primary citation: Mao, E.Y.C.,Yen, H.Y.,Wu, C.C.; Structural basis of how MGME1 processes DNA 5' ends to maintain mitochondrial genome integrity.; Nucleic Acids Res., 2024; PubMed: 38471810; DOI: 10.1093/nar/gkae186

Experimental method

X-RAY DIFFRACTION (2.32 Å)