8X8T

NMR structure of p75NTR juxtamembrane domain in complex with RhoGDI N-terminal domain containing a phosphorylation-mimicking S34D mutation

Summary for 8X8T

• Entry DOI: 10.2210/pdb8x8t/pdb
• Descriptor: Rho GDP-dissociation inhibitor 1, Tumor necrosis factor receptor superfamily member 16 (2 entities in total)
• Functional Keywords: inhibitor, complex, signaling, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 13536.53

Authors

Lin, Z.,Li, Z. (deposition date: 2023-11-28, release date: 2024-04-03, Last modification date: 2024-05-15)

• Primary citation: Ramanujan, A.,Li, Z.,Ma, Y.,Lin, Z.,Ibanez, C.F.; RhoGDI phosphorylation by PKC promotes its interaction with death receptor p75 NTR to gate axon growth and neuron survival.; Embo Rep., 25:1490-1512, 2024; PubMed: 38253689; DOI: 10.1038/s44319-024-00064-2

Experimental method

SOLUTION NMR