8X8Q

Structure of enterovirus protease in complex host factor

Summary for 8X8Q

• Entry DOI: 10.2210/pdb8x8q/pdb
• EMDB information: 38156
• Descriptor: Actin-histidine N-methyltransferase, 2A protein (Fragment), ZINC ION (3 entities in total)
• Functional Keywords: host protein, viral protein, cell invasion, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 83969.87

Authors

Gao, X.,Cui, S. (deposition date: 2023-11-28, release date: 2024-05-29)

• Primary citation: Gao, X.,Wang, B.,Zhu, K.,Wang, L.,Qin, B.,Shang, K.,Ding, W.,Wang, J.,Cui, S.; The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction.; Nat Commun, 15:4176-4176, 2024; PubMed: 38755176; DOI: 10.1038/s41467-024-48504-w

Experimental method

ELECTRON MICROSCOPY (3.14 Å)