8XAJ

Cryo-EM structure of OSCA1.2-liposome-inside-in open state

Summary for 8XAJ

• Entry DOI: 10.2210/pdb8xaj/pdb
• EMDB information: 38200
• Descriptor: Calcium permeable stress-gated cation channel 1, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (2 entities in total)
• Functional Keywords: osca/tmem63 channel, mechanosensitive channel, plant protein
• Biological source: Arabidopsis thaliana (thale cress)
• Total number of polymer chains: 2
• Total formula weight: 181480.94

Authors

Zhang, Y.,Han, Y. (deposition date: 2023-12-04, release date: 2024-04-10, Last modification date: 2024-04-17)

• Primary citation: Han, Y.,Zhou, Z.,Jin, R.,Dai, F.,Ge, Y.,Ju, X.,Ma, X.,He, S.,Yuan, L.,Wang, Y.,Yang, W.,Yue, X.,Chen, Z.,Sun, Y.,Corry, B.,Cox, C.D.,Zhang, Y.; Mechanical activation opens a lipid-lined pore in OSCA ion channels.; Nature, 2024; PubMed: 38570680; DOI: 10.1038/s41586-024-07256-9

Experimental method

ELECTRON MICROSCOPY (3.29 Å)