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1F6B
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BU of 1f6b by Molmil
CRYSTAL STRUCTURE OF SAR1-GDP COMPLEX
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SAR1, ...
Authors:Huang, M, Wilson, I.A, Balch, W.E.
Deposit date:2000-06-21
Release date:2002-01-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Sar1-GDP at 1.7 A resolution and the role of the NH2 terminus in ER export.
J.Cell Biol., 155, 2001
1F5X
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BU of 1f5x by Molmil
NMR STRUCTURE OF THE Y174 AUTOINHIBITED DBL HOMOLOGY DOMAIN
Descriptor: RHO-GEF VAV
Authors:Aghazadeh, B, Rosen, M.K, Lowry, W.E, Huang, X.Y.
Deposit date:2000-06-18
Release date:2000-09-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation.
Cell(Cambridge,Mass.), 102, 2000
1KB8
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BU of 1kb8 by Molmil
A COMPARISON OF NMR SOLUTION STRUCTURES OF THE RECEPTOR BINDING DOMAINS OF PSEUDOMONAS AERUGINOSA PILI STRAINS PAO, KB7, AND PAK: IMPLICATIONS FOR RECEPTOR BINDING AND SYNTHETIC VACCINE DESIGN
Descriptor: KB7 PILIN, TRANS
Authors:Campbell, A.P, Mcinnes, C, Hodges, R.S, Sykes, B.D.
Deposit date:1995-10-05
Release date:1996-01-29
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Comparison of NMR solution structures of the receptor binding domains of Pseudomonas aeruginosa pili strains PAO, KB7, and PAK: implications for receptor binding and synthetic vaccine design.
Biochemistry, 34, 1995
1HTR
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BU of 1htr by Molmil
CRYSTAL AND MOLECULAR STRUCTURES OF HUMAN PROGASTRICSIN AT 1.62 ANGSTROMS RESOLUTION
Descriptor: GASTRICSIN, PROGASTRICSIN (PRO SEGMENT)
Authors:Moore, S.A, Sielecki, A.R, James, M.N.G.
Deposit date:1994-10-21
Release date:1995-01-26
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal and molecular structures of human progastricsin at 1.62 A resolution.
J.Mol.Biol., 247, 1995
1FJ5
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BU of 1fj5 by Molmil
TAMOXIFEN-DNA ADDUCT
Descriptor: (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINIUM, DNA (5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3')
Authors:Shimotakahara, S, Gorin, A, Kolbanovskiy, A, Kettani, A, Hingerty, B.E, Amin, S, Broyde, S, Geacintov, N, Patel, D.J.
Deposit date:2000-08-07
Release date:2000-09-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Accomodation of S-cis-tamoxifen-N(2)-guanine adduct within a bent and widened DNA minor groove.
J.Mol.Biol., 302, 2000
2OH4
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BU of 2oh4 by Molmil
Crystal structure of Vegfr2 with a benzimidazole-urea inhibitor
Descriptor: METHYL (5-{4-[({[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-1H-BENZIMIDAZOL-2-YL)CARBAMATE, SULFATE ION, Vascular endothelial growth factor receptor 2
Authors:Nolte, R.T, Wang, L.
Deposit date:2007-01-09
Release date:2007-09-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery of Novel Benzimidazoles as Potent Inhibitors of TIE-2 and VEGFR-2 Tyrosine Kinase Receptors.
J.Med.Chem., 50, 2007
1FNN
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BU of 1fnn by Molmil
CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CELL DIVISION CONTROL PROTEIN 6, MAGNESIUM ION
Authors:Liu, J, Smith, C.L, DeRyckere, D, DeAngelis, K, Martin, G.S, Berger, J.M.
Deposit date:2000-08-22
Release date:2000-10-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control.
Mol.Cell, 6, 2000
2KHN
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BU of 2khn by Molmil
NMR solution structure of the EH 1 domain from human intersectin-1 protein. Northeast Structural Genomics Consortium target HR3646E.
Descriptor: Intersectin-1
Authors:Mills, J.L, Ghosh, A, Garcia, E, Zhang, Q, Shastry, R, Foote, E.L, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-04-09
Release date:2009-04-21
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR solution structure of the EH 1 domain from human intersectin-1 protein. Northeast Structural Genomics Consortium target HR3646E.
To be Published
2KI6
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BU of 2ki6 by Molmil
The FGF1-S100A13-C2A hetero-hexameric complex structure: A component in the non-classical pathway for FGF1 secretion
Descriptor: Heparin-binding growth factor 1, Protein S100-A13, Synaptotagmin-1
Authors:Krishna, S.M, Rani, S.G, Yu, C.
Deposit date:2009-04-28
Release date:2010-03-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion.
J.Biol.Chem., 285, 2010
2KMC
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BU of 2kmc by Molmil
Solution Structure of the N-terminal domain of kindlin-1
Descriptor: Fermitin family homolog 1
Authors:Goult, B.T, Bate, N, Roberts, G.C, Barsukov, I.L, Critchley, D.R.
Deposit date:2009-07-27
Release date:2009-10-06
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The Structure of the N-Terminus of Kindlin-1: A Domain Important for alphaIIbbeta3 Integrin Activation
J.Mol.Biol., 394, 2009
1JPT
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BU of 1jpt by Molmil
Crystal Structure of Fab D3H44
Descriptor: immunoglobulin Fab D3H44, heavy chain, immunoglobulin Fab D3h44, ...
Authors:Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A.
Deposit date:2001-08-03
Release date:2002-02-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
2KNB
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BU of 2knb by Molmil
Solution NMR structure of the parkin Ubl domain in complex with the endophilin-A1 SH3 domain
Descriptor: E3 ubiquitin-protein ligase parkin, Endophilin-A1
Authors:Trempe, J, Guennadi, K, Edna, C.M, Kalle, G.
Deposit date:2009-08-20
Release date:2009-12-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol.Cell, 36, 2009
1CS0
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BU of 1cs0 by Molmil
Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ...
Authors:Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M.
Deposit date:1999-08-16
Release date:1999-12-10
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
2K9U
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BU of 2k9u by Molmil
Solution NMR structure of the Filamin-migfilin complex
Descriptor: Filamin-binding LIM protein 1, Gamma filamin
Authors:Ithychanda, S.N, Qin, J.
Deposit date:2008-10-24
Release date:2008-12-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Migfilin, a molecular switch in regulation of integrin activation.
J.Biol.Chem., 284, 2009
2KGR
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BU of 2kgr by Molmil
Solution structure of protein ITSN1 from Homo sapiens. Northeast Structural Genomics Consortium target HR5524A
Descriptor: Intersectin-1
Authors:Wu, Y, Ghosh, A, Shastry, R, Hua, J, Ciccosanti, C, Zhang, Q, Jiang, M, Swapna, G, Acton, T, Xiao, R, Everett, J, Montelione, G, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-03-16
Release date:2009-03-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of protein ITSN1 from Homo sapiens. Northeast Structural Genomics Consortium target HR5524A
To be Published
2O8C
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BU of 2o8c by Molmil
human MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispair
Descriptor: 5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*(6OG)P*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
1ETM
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BU of 1etm by Molmil
STRUCTURAL CHARACTERISTICS FOR BIOLOGICAL ACTIVITY OF HEAT-STABLE ENTEROTOXIN PRODUCED BY ENTEROTOXIGENIC ESCHERICHIA COLI: X-RAY CRYSTALLOGRAPHY OF WEAKLY TOXIC AND NONTOXIC ANALOGS
Descriptor: 5-BETA-MERCAPTOPROPIONATE HEAT-STABLE ENTEROTOXIN
Authors:Sato, T, Shimonishi, Y.
Deposit date:1994-03-15
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (0.89 Å)
Cite:Structural characteristics for biological activity of heat-stable enterotoxin produced by enterotoxigenic Escherichia coli: X-ray crystallography of weakly toxic and nontoxic analogs.
Biochemistry, 33, 1994
1KB7
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BU of 1kb7 by Molmil
A COMPARISON OF NMR SOLUTION STRUCTURES OF THE RECEPTOR BINDING DOMAINS OF PSEUDOMONAS AERUGINOSA PILI STRAINS PAO, KB7, AND PAK: IMPLICATIONS FOR RECEPTOR BINDING AND SYNTHETIC VACCINE DESIGN
Descriptor: KB7 PILIN, TRANS
Authors:Campbell, A.P, Mcinnes, C, Hodges, R.S, Sykes, B.D.
Deposit date:1995-10-05
Release date:1996-01-29
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Comparison of NMR solution structures of the receptor binding domains of Pseudomonas aeruginosa pili strains PAO, KB7, and PAK: implications for receptor binding and synthetic vaccine design.
Biochemistry, 34, 1995
2MNR
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BU of 2mnr by Molmil
MECHANISM OF THE REACTION CATALYZED BY MANDELATE RACEMASE. 2. CRYSTAL STRUCTURE OF MANDELATE RACEMASE AT 2.5 ANGSTROMS RESOLUTION: IDENTIFICATION OF THE ACTIVE SITE AND POSSIBLE CATALYTIC RESIDUES
Descriptor: MANDELATE RACEMASE, MANGANESE (II) ION, SULFATE ION
Authors:Neidhart, D.J, Petsko, G.A.
Deposit date:1993-07-06
Release date:1994-01-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-A resolution: identification of the active site and possible catalytic residues.
Biochemistry, 30, 1991
1KEX
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BU of 1kex by Molmil
Crystal Structure of the b1 Domain of Human Neuropilin-1
Descriptor: Neuropilin-1
Authors:Lee, C.C, Kreusch, A, McMullan, D, Ng, K, Spraggon, G.
Deposit date:2001-11-18
Release date:2003-01-28
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Human Neuropilin-1 b1 Domain
Structure, 11, 2003
2OJG
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BU of 2ojg by Molmil
Crystal structure of ERK2 in complex with N,N-dimethyl-4-(4-phenyl-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
Descriptor: Mitogen-activated protein kinase 1, N,N-DIMETHYL-4-(4-PHENYL-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE, SULFATE ION
Authors:Xie, X, Jacobs, M.D.
Deposit date:2007-01-12
Release date:2007-02-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors.
J.Med.Chem., 50, 2007
2OJF
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BU of 2ojf by Molmil
Crystal structure of Protein Kinase A in complex with Pyridine-Pyrazolopyridine based inhibitors
Descriptor: (2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE, Inhibitory peptide, cAMP-dependent protein kinase, ...
Authors:Stoll, V.S.
Deposit date:2007-01-12
Release date:2007-03-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design and synthesis of pyridine-pyrazolopyridine-based inhibitors of protein kinase B/Akt.
Bioorg.Med.Chem., 15, 2007
2K9G
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BU of 2k9g by Molmil
Solution structure of the third SH3 domain of the Cin85 adapter protein
Descriptor: SH3 domain-containing kinase-binding protein 1
Authors:Philippe, D.L, Ladbury, J.E, Pfuhl, M.
Deposit date:2008-10-10
Release date:2009-10-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the Sh3-C domain of Cin85
To be Published
2K8X
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GlyTM1b(1-19)zip: A Chimeric Peptide Model of the N-Terminus of a Rat Short Alpha-Tropomyosin with the N-Terminus Encoded by Exon 1b in Complex with TM9d(252-284), a Peptide Model Containing the C Terminus of Alpha-Tropomyosin Encoded by Exon 9d
Descriptor: TM1b(1-19)Zip
Authors:Greenfield, N.J, Kotylanskaya, L, Hitchcock-DeGregori, S.E.
Deposit date:2008-09-25
Release date:2009-04-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the N terminus of a nonmuscle alpha-tropomyosin in complex with the C terminus: implications for actin binding.
Biochemistry, 48, 2009
2OJJ
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BU of 2ojj by Molmil
Crystal structure of ERK2 in complex with (S)-N-(1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl)-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
Descriptor: (S)-N-(1-(3-CHLORO-4-FLUOROPHENYL)-2-HYDROXYETHYL)-4-(4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE, Mitogen-activated protein kinase 1, SULFATE ION
Authors:Xie, X, Jacobs, M.D.
Deposit date:2007-01-12
Release date:2007-02-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors.
J.Med.Chem., 50, 2007

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