2KI6
The FGF1-S100A13-C2A hetero-hexameric complex structure: A component in the non-classical pathway for FGF1 secretion
Summary for 2KI6
Entry DOI | 10.2210/pdb2ki6/pdb |
Descriptor | Synaptotagmin-1, Heparin-binding growth factor 1, Protein S100-A13, ... (4 entities in total) |
Functional Keywords | fgf1-s100a13-c2a hetero-hexameric complex, fgf1, s100a13, c2a, calcium, cell junction, cytoplasmic vesicle, glycoprotein, lipoprotein, membrane, metal-binding, palmitate, phosphoprotein, synapse, transmembrane, acetylation, alternative splicing, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, protein transport |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P21579 Secreted: P05230 Cytoplasm: Q99584 Q99584 |
Total number of polymer chains | 6 |
Total formula weight | 82781.22 |
Authors | Krishna, S.M.,Rani, S.G.,Yu, C. (deposition date: 2009-04-28, release date: 2010-03-09, Last modification date: 2011-07-13) |
Primary citation | Mohan, S.K.,Rani, S.G.,Yu, C. The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion. J.Biol.Chem., 285:15464-15475, 2010 Cited by PubMed: 20220137DOI: 10.1074/jbc.M109.066357 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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