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7VCM
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BU of 7vcm by Molmil
crystal structure of GINKO1
Descriptor: Green fluorescent protein,Potassium binding protein Kbp,Green fluorescent protein, POTASSIUM ION
Authors:Wen, Y, Campbell, R.E, Lemieux, M.J.
Deposit date:2021-09-03
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A sensitive and specific genetically-encoded potassium ion biosensor for in vivo applications across the tree of life.
Plos Biol., 20, 2022
4M8T
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BU of 4m8t by Molmil
RSK2 T493M C-Terminal Kinase Domain in complex with 3-(3-(1H-pyrazol-4-yl)phenyl)-2-cyanoacrylamide
Descriptor: (2E)-2-cyano-3-[3-(1H-pyrazol-4-yl)phenyl]prop-2-enamide, Ribosomal protein S6 kinase alpha-3, SODIUM ION
Authors:Miller, R.M, Taunton, J.
Deposit date:2013-08-13
Release date:2014-10-22
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (3 Å)
Cite:Covalent docking of large libraries for the discovery of chemical probes.
Nat.Chem.Biol., 10, 2014
5EZP
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BU of 5ezp by Molmil
Human transthyretin (TTR) complexed with 4-hydroxy-chalcone
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-chalcone, Transthyretin
Authors:Polsinelli, I, Nencetti, S, Shepard, W.E, Orlandini, E, Stura, E.A.
Deposit date:2015-11-26
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A new crystal form of human transthyretin obtained with a curcumin derived ligand.
J.Struct.Biol., 194, 2016
4MQV
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BU of 4mqv by Molmil
Crystal complex of Rpa32c and Smarcal1 N-terminus
Descriptor: Replication protein A 32 kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
Authors:Xie, S, Qian, C.M.
Deposit date:2013-09-16
Release date:2014-07-02
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of RPA32 bound to the N-terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins
Febs J., 281, 2014
6ZA0
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BU of 6za0 by Molmil
Structure of the transcriptional repressor Atu1419 (VanR) in complex with a fortuitous citrate from agrobacterium fabrum (P21212 space group)
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Morera, S, Vigouroux, A, Legrand, P.
Deposit date:2020-06-04
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
6ZA3
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BU of 6za3 by Molmil
Structure of the transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum in complex a palindromic DNA (C2221 space group)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Morera, S, Vigouroux, A, Legrand, P.
Deposit date:2020-06-04
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
6Z74
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BU of 6z74 by Molmil
Structure of the transcriptional repressor Atu1419 (VanR) in complex with a fortuitous citrate from agrobacterium fabrum
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Morera, S, Vigouroux, V.
Deposit date:2020-05-29
Release date:2020-12-02
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
6ZAB
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BU of 6zab by Molmil
Structure of the transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum in complex a palindromic DNA (P6422 space group)
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Morera, S, Naretto, A, Vigouroux, A, Legrand, P.
Deposit date:2020-06-05
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
5FA5
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BU of 5fa5 by Molmil
Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Histone H4, Methylosome protein 50, ...
Authors:Sprague, E.R, McNamara, J.T.
Deposit date:2015-12-10
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Science, 351, 2016
4ZFQ
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BU of 4zfq by Molmil
Structure of M. tuberculosis (3,3) L,D-Transpeptidase, LdtMt5. (Meropenen-adduct form)
Descriptor: (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, DI(HYDROXYETHYL)ETHER, L,D-transpeptidase 5
Authors:Basta, L, Ghosh, A, Lamichhane, G, Bianchet, M.A.
Deposit date:2015-04-21
Release date:2015-09-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
4LV0
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BU of 4lv0 by Molmil
AmpC beta-lactamase in complex with m-aminophenyl boronic acid
Descriptor: Beta-lactamase, M-AMINOPHENYLBORONIC ACID, PHOSPHATE ION
Authors:London, N, Eidam, O, Shoichet, B.K.
Deposit date:2013-07-25
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.652 Å)
Cite:Covalent docking of large libraries for the discovery of chemical probes.
Nat.Chem.Biol., 10, 2014
4MB8
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BU of 4mb8 by Molmil
Evolutionary history and metabolic insights of ancient mammalian uricases
Descriptor: ACETATE ION, Uricase
Authors:Ortlund, E.O, Murphy, M.N.
Deposit date:2013-08-19
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4009 Å)
Cite:Evolutionary history and metabolic insights of ancient mammalian uricases.
Proc.Natl.Acad.Sci.USA, 111, 2014
7A1R
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BU of 7a1r by Molmil
Crystal structure of the C2B domain of Trypanosoma brucei extended synaptotagmin (E-Syt)
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Dong, G.
Deposit date:2020-08-13
Release date:2021-06-02
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei .
Iscience, 24, 2021
6ZXQ
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BU of 6zxq by Molmil
Adenylosuccinate Synthetase from H. pylori in complex with HDA, GDP, IMO, Mg
Descriptor: 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE, Adenylosuccinate synthetase, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Bubic, A, Stefanic, Z.
Deposit date:2020-07-30
Release date:2021-08-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site
Int.J.Biol.Macromol., 2023
6ZA7
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BU of 6za7 by Molmil
Structure of the apo transcriptional repressor Atu1419 (VanR) from agrobacterium fabrum
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ...
Authors:Morera, S, Vigouroux, A, Legrand, P.
Deposit date:2020-06-04
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Characterization of the first tetrameric transcription factor of the GntR superfamily with allosteric regulation from the bacterial pathogen Agrobacterium fabrum.
Nucleic Acids Res., 49, 2021
7N7O
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BU of 7n7o by Molmil
Crystal Structure of PI5P4KIIAlpha complex with Palbociclib
Descriptor: 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION
Authors:Chen, S, Ha, Y.
Deposit date:2021-06-10
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells.
Proc.Natl.Acad.Sci.USA, 118, 2021
5DTI
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BU of 5dti by Molmil
Crystal structure of mouse acetylcholinesterase
Descriptor: Acetylcholinesterase
Authors:Tran, T.H, Tong, L.
Deposit date:2015-09-18
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates.
Chembiochem, 16, 2015
4LV2
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BU of 4lv2 by Molmil
AmpC beta-lactamase in complex with [1-(6-chloropyrimidin-4-yl)-1H-pyrazol-4-yl] boronic acid
Descriptor: Beta-lactamase, PHOSPHATE ION, [1-(6-chloropyrimidin-4-yl)-1H-pyrazol-4-yl]boronic acid
Authors:London, N, Eidam, O, Shoichet, B.K.
Deposit date:2013-07-25
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Covalent docking of large libraries for the discovery of chemical probes.
Nat.Chem.Biol., 10, 2014
4X3S
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BU of 4x3s by Molmil
Crystal structure of chromobox homology 7 (CBX7) with SETDB1-1170me3 Peptide
Descriptor: CITRIC ACID, Chromobox protein homolog 7, FE (III) ION, ...
Authors:Ren, C, Plotnikov, A.N, Zhou, M.M.
Deposit date:2014-12-01
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
Chem.Biol., 22, 2015
4LV1
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BU of 4lv1 by Molmil
AmpC beta-lactamase in complex with [1-(3-chlorophenyl)-1H-pyrazol-4-yl] boronic acid
Descriptor: Beta-lactamase, PHOSPHATE ION, [1-(3-chlorophenyl)-1H-pyrazol-4-yl]boronic acid
Authors:London, N, Eidam, O, Shoichet, B.K.
Deposit date:2013-07-25
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Covalent docking of large libraries for the discovery of chemical probes.
Nat.Chem.Biol., 10, 2014
8OIP
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BU of 8oip by Molmil
28S mammalian mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA
Descriptor: 12S rRNA, 28S ribosomal protein S15, mitochondrial, ...
Authors:Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
Deposit date:2023-03-23
Release date:2023-05-24
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
8OIS
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BU of 8ois by Molmil
28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA
Descriptor: 12S rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
Deposit date:2023-03-23
Release date:2023-06-14
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
8OIT
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BU of 8oit by Molmil
39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA
Descriptor: 16S rRNA, 39S ribosomal protein L1, mitochondrial, ...
Authors:Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
Deposit date:2023-03-23
Release date:2023-06-14
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
8OIR
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BU of 8oir by Molmil
55S human mitochondrial ribosome with mtRF1 and P-site tRNA
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
Authors:Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
Deposit date:2023-03-23
Release date:2023-06-14
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
8OIQ
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BU of 8oiq by Molmil
39S mammalian mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA
Descriptor: 16S rRNA, 39S ribosomal protein L1, mitochondrial, ...
Authors:Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
Deposit date:2023-03-23
Release date:2023-06-14
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023

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数据于2024-10-16公开中

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