4ZFQ

Structure of M. tuberculosis (3,3) L,D-Transpeptidase, LdtMt5. (Meropenen-adduct form)

Summary for 4ZFQ

Entry DOI	10.2210/pdb4zfq/pdb
Related	4Z7A
Descriptor	L,D-transpeptidase 5, DI(HYDROXYETHYL)ETHER, (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, ... (4 entities in total)
Functional Keywords	peptidoglycan linkage, cell wall biosynthesis, carbapenems, mycobaterium tuberculosis, l.d-transpeptidases, transferase
Biological source	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Total number of polymer chains	1
Total formula weight	48530.23
Authors	Basta, L.,Ghosh, A.,Lamichhane, G.,Bianchet, M.A. (deposition date: 2015-04-21, release date: 2015-09-02, Last modification date: 2023-09-27)
Primary citation	Brammer Basta, L.A.,Ghosh, A.,Pan, Y.,Jakoncic, J.,Lloyd, E.P.,Townsend, C.A.,Lamichhane, G.,Bianchet, M.A. Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis. J.Biol.Chem., 290:25670-25685, 2015 Cited by PubMed: 26304120 DOI: 10.1074/jbc.M115.660753 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.799 Å)

Structure validation