PDB: 41522 resultsInfo pagesStatus searchChemie searchBIRD

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4ZV2	An ancestral arginine-binding protein bound to glutamine Descriptor: AncQR, GLUTAMINE Authors: Clifton, B.E, Jackson, C.J. Deposit date: 2015-05-18 Release date: 2016-02-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Ancestral Protein Reconstruction Yields Insights into Adaptive Evolution of Binding Specificity in Solute-Binding Proteins. Cell Chem Biol, 23, 2016
1A28	HORMONE-BOUND HUMAN PROGESTERONE RECEPTOR LIGAND-BINDING DOMAIN Descriptor: PROGESTERONE, PROGESTERONE RECEPTOR Authors: Sigler, P.B, Williams, S.P. Deposit date: 1998-01-19 Release date: 1998-07-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Atomic structure of progesterone complexed with its receptor. Nature, 393, 1998
6XR4	Integrative in situ structure of Parkinsons disease-linked human LRRK2 Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2 Authors: Villa, E, Lasker, K, Audagnotto, M. Deposit date: 2020-07-10 Release date: 2020-08-19 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (14 Å) Cite: The In Situ Structure of Parkinson's Disease-Linked LRRK2. Cell, 182, 2020
1MR0	SOLUTION NMR STRUCTURE OF AGRP(87-120; C105A) Descriptor: AGOUTI RELATED PROTEIN Authors: Jackson, P.J, Mcnulty, J.C, Yang, Y.K, Thompson, D.A, Chai, B, Gantz, I, Barsh, G.S, Millhauser, G.M. Deposit date: 2002-09-17 Release date: 2002-10-02 Last modified: 2021-10-27 Method: SOLUTION NMR Cite: Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity. Biochemistry, 41, 2002
6XGU	Crystal Structure of KRAS-Q61R (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF Descriptor: GLYCEROL, GTPase KRas, MAGNESIUM ION, ... Authors: Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K. Deposit date: 2020-06-18 Release date: 2021-01-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.7 Å) Cite: KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nat Commun, 12, 2021
6RAK	Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing occluded conformation Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ... Authors: Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. Deposit date: 2019-04-06 Release date: 2019-07-31 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
5W3J	Yeast microtubule stabilized with Taxol assembled from mutated tubulin Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Howes, S.C, Geyer, E.A, LaFrance, B, Zhang, R, Kellogg, E.H, Westermann, S, Rice, L.M, Nogales, E. Deposit date: 2017-06-07 Release date: 2017-07-19 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural differences between yeast and mammalian microtubules revealed by cryo-EM. J. Cell Biol., 216, 2017
8CQB	Cryo-EM structure of the human GBP1 dimer bound to GDP-AlF3 Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 1, ... Authors: Kuhm, T.I, Jakobi, A.J. Deposit date: 2023-03-04 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structure of the human GBP1 dimer bound to GDP-AlF3 To Be Published
4ZSV	Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-1.0 Descriptor: Uncharacterized protein Authors: Lai, Y.-T, Yeates, T.O. Deposit date: 2015-05-14 Release date: 2015-08-19 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (4.2 Å) Cite: On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker. Protein Eng.Des.Sel., 28, 2015
1MTN	BOVINE ALPHA-CHYMOTRYPSIN:BPTI CRYSTALLIZATION Descriptor: ALPHA-CHYMOTRYPSIN, BASIC PANCREATIC TRYPSIN INHIBITOR, SULFATE ION Authors: Capasso, C, Rizzi, M, Menegatti, E, Ascenzi, P, Bolognesi, M. Deposit date: 1996-03-28 Release date: 1996-08-17 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of the bovine alpha-chymotrypsin:Kunitz inhibitor complex. An example of multiple protein:protein recognition sites. J.Mol.Recog., 10, 1997
5W0K	Crystal structure of EBV gHgL/CL40/gp42 N-domain Descriptor: CL40 IgG heavy chain, CL40 IgG light chain, Envelope glycoprotein H, ... Authors: Sathiyamoorthy, K, Jardetzky, T.S. Deposit date: 2017-05-31 Release date: 2017-10-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1VNA	PROTON NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY(SLASH)SIMULATED ANNEALING STUDIES ON THE VARIANT-1 NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING Descriptor: NEUROTOXIN Authors: Lee, W, Krishna, N.R. Deposit date: 1993-10-26 Release date: 1994-01-31 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Proton nuclear magnetic resonance and distance geometry/simulated annealing studies on the variant-1 neurotoxin from the New World scorpion Centruroides sculpturatus Ewing. Biochemistry, 33, 1994
4ZSZ	Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-3.0 Descriptor: Uncharacterized Fusion Protein Authors: Lai, Y.-T, Yeates, T.O. Deposit date: 2015-05-14 Release date: 2015-08-19 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (4.251 Å) Cite: On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker. Protein Eng.Des.Sel., 28, 2015
5W1F	Crystal structure of Ni(II)- and Ca(II)-bound human calprotectin Descriptor: CALCIUM ION, NICKEL (II) ION, Protein S100-A8, ... Authors: Nakashige, T.G, Drennan, C.L, Nolan, E.M. Deposit date: 2017-06-03 Release date: 2017-06-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Nickel Sequestration by the Host-Defense Protein Human Calprotectin. J. Am. Chem. Soc., 139, 2017
1VNB	PROTON NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY(SLASH)SIMULATED ANNEALING STUDIES ON THE VARIANT-1 NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING Descriptor: NEUROTOXIN Authors: Lee, W, Krishna, N.R. Deposit date: 1993-10-26 Release date: 1994-01-31 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Proton nuclear magnetic resonance and distance geometry/simulated annealing studies on the variant-1 neurotoxin from the New World scorpion Centruroides sculpturatus Ewing. Biochemistry, 33, 1994
6XBZ	Structure of the human CDK-activating kinase Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... Authors: Greber, B.J, Perez-Bertoldi, J.M, Lim, K, Iavarone, A.T, Toso, D.B, Nogales, E. Deposit date: 2020-06-07 Release date: 2020-09-09 Last modified: 2020-09-30 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: The cryoelectron microscopy structure of the human CDK-activating kinase. Proc.Natl.Acad.Sci.USA, 117, 2020
3VBT	Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design Descriptor: 4-chloro-2-(1H-pyrazol-3-yl)phenol, Serine/threonine-protein kinase pim-1 Authors: Liu, J. Deposit date: 2012-01-02 Release date: 2012-03-21 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design. J.Med.Chem., 55, 2012
4ZTE	Crystal structure of human E-Cadherin (residues 3-213) in complex with a peptidomimetic inhibitor Descriptor: CALCIUM ION, Cadherin-1, N-{[(2S,5S)-1-benzyl-5-(2-{[(2S,3S)-1-(tert-butylamino)-3-methyl-1-oxopentan-2-yl]amino}-2-oxoethyl)-3,6-dioxopiperazin-2-yl]methyl}-L-alpha-asparagine Authors: Nardone, V, Lucarelli, A.P, Dalle Vedove, A, Parisini, E. Deposit date: 2015-05-14 Release date: 2016-06-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Competitive Inhibitor of Cadherin Homophilic Interaction. J.Med.Chem., 59, 2016
5W5B	Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c), truncated construct Descriptor: CHLORIDE ION, HTH-type transcriptional regulator Cmr Authors: Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A. Deposit date: 2017-06-14 Release date: 2017-12-13 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria. Nucleic Acids Res., 46, 2018
5W2A	Structure of human DNA polymerase kappa in complex with Lucidin-derived DNA adduct and incoming dCMPNPP Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*TP*GP*(LDG)P*CP*TP*GP*AP*TP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*TP*CP*AP*G)-3'), ... Authors: Jha, V.K, Ling, H. Deposit date: 2017-06-06 Release date: 2017-10-18 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase kappa. Chem. Res. Toxicol., 30, 2017
4V8Q	Complex of SmpB, a tmRNA fragment and EF-Tu-GDP-Kirromycin with the 70S ribosome Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... Authors: Neubauer, C, Gillet, R, Kelley, A.C, Ramakrishnan, V. Deposit date: 2011-12-10 Release date: 2014-07-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Decoding in the absence of a codon by tmRNA and SmpB in the ribosome. Science, 335, 2012
5W2J	Crystal structure of dimeric form of mouse Glutaminase C Descriptor: CHLORIDE ION, Glutaminase kidney isoform, mitochondrial, ... Authors: Cerione, R.A, Li, Y. Deposit date: 2017-06-06 Release date: 2018-10-17 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS. J. Biol. Chem., 291, 2016
4V83	Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S ribosome. Descriptor: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S. Deposit date: 2010-12-13 Release date: 2014-07-09 Last modified: 2014-12-10 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 108, 2011
6UX2	Crystal structure of ZIKV RdRp in complex with STAT2 Descriptor: Nonstructural Protein 5, SULFATE ION, Signal transducer and activator of transcription 2, ... Authors: Wang, B, Song, J. Deposit date: 2019-11-06 Release date: 2020-07-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Structural basis for STAT2 suppression by flavivirus NS5. Nat.Struct.Mol.Biol., 27, 2020
5W3O	CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, empty particle) Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ... Authors: Liu, Y, Dong, Y, Rossmann, M.G. Deposit date: 2017-06-08 Release date: 2017-07-12 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Antibody-induced uncoating of human rhinovirus B14. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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