6XBZ

Structure of the human CDK-activating kinase

Summary for 6XBZ

Entry DOI	10.2210/pdb6xbz/pdb
EMDB information	22123
Descriptor	CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... (5 entities in total)
Functional Keywords	kinase, transcription, cell cycle, complex, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	120106.42
Authors	Greber, B.J.,Perez-Bertoldi, J.M.,Lim, K.,Iavarone, A.T.,Toso, D.B.,Nogales, E. (deposition date: 2020-06-07, release date: 2020-09-09, Last modification date: 2020-09-30)
Primary citation	Greber, B.J.,Perez-Bertoldi, J.M.,Lim, K.,Iavarone, A.T.,Toso, D.B.,Nogales, E. The cryoelectron microscopy structure of the human CDK-activating kinase. Proc.Natl.Acad.Sci.USA, 117:22849-22857, 2020 Cited by PubMed: 32855301 DOI: 10.1073/pnas.2009627117 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation