6XBZ
Structure of the human CDK-activating kinase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | CDK-activating kinase assembly factor MAT1 | polymer | 328 | 38132.3 | 1 | UniProt (P51948) Pfam (PF17121) Pfam (PF06391) In PDB | Homo sapiens (Human) | CDK7/cyclin-H assembly factor,Cyclin-G1-interacting protein,Menage a trois,RING finger protein 66,RING finger protein MAT1,p35,p36 |
2 | I | Cyclin-H | polymer | 323 | 37695.5 | 1 | UniProt (P51946) Pfam (PF00134) Pfam (PF16899) In PDB | Homo sapiens (Human) | MO15-associated protein,p34,p37 |
3 | J | Cyclin-dependent kinase 7 | polymer | 391 | 43731.1 | 1 | UniProt (P50613) Pfam (PF00069) In PDB | Homo sapiens (Human) | 39 kDa protein kinase,p39 Mo15,CDK-activating kinase 1,Cell division protein kinase 7,Serine/threonine-protein kinase 1,TFIIH basal transcription factor complex kinase subunit |
4 | J | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | J | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 1 | Chemie (AGS) |
Sequence modifications
H: 1 - 309 (UniProt: P51948)
J: 1 - 346 (UniProt: P50613)
PDB | External Database | Details |
---|---|---|
Met -18 | - | initiating methionine |
Gly -17 | - | expression tag |
Ser -16 | - | expression tag |
Ser -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Glu -8 | - | expression tag |
Asn -7 | - | expression tag |
Leu -6 | - | expression tag |
Tyr -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Ala 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -44 | - | initiating methionine |
Ala -43 | - | expression tag |
Ser -42 | - | expression tag |
Trp -41 | - | expression tag |
Ser -40 | - | expression tag |
His -39 | - | expression tag |
Pro -38 | - | expression tag |
Gln -37 | - | expression tag |
Phe -36 | - | expression tag |
Glu -35 | - | expression tag |
Lys -34 | - | expression tag |
Gly -33 | - | expression tag |
Gly -32 | - | expression tag |
Gly -31 | - | expression tag |
Ser -30 | - | expression tag |
Gly -29 | - | expression tag |
Gly -28 | - | expression tag |
Gly -27 | - | expression tag |
Ser -26 | - | expression tag |
Gly -25 | - | expression tag |
Gly -24 | - | expression tag |
Gly -23 | - | expression tag |
Ser -22 | - | expression tag |
Trp -21 | - | expression tag |
Ser -20 | - | expression tag |
His -19 | - | expression tag |
Pro -18 | - | expression tag |
Gln -17 | - | expression tag |
Phe -16 | - | expression tag |
Glu -15 | - | expression tag |
Lys -14 | - | expression tag |
Ser -13 | - | expression tag |
Gly -12 | - | expression tag |
Gly -11 | - | expression tag |
Gly -10 | - | expression tag |
Ser -9 | - | expression tag |
Glu -8 | - | expression tag |
Asn -7 | - | expression tag |
Leu -6 | - | expression tag |
Tyr -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 119558.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 547.6 | |
All* | Total formula weight | 120106.4 |