5W3J

Yeast microtubule stabilized with Taxol assembled from mutated tubulin

Summary for 5W3J

• Entry DOI: 10.2210/pdb5w3j/pdb
• Related: 5W3F 5W3H
• EMDB information: 8755 8756 8757 8758 8759
• Descriptor: Tubulin alpha-1 chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: cytoskeleton, tubulin, hydrolase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 2
• Total formula weight: 102788.13

Authors

Howes, S.C.,Geyer, E.A.,LaFrance, B.,Zhang, R.,Kellogg, E.H.,Westermann, S.,Rice, L.M.,Nogales, E. (deposition date: 2017-06-07, release date: 2017-07-19, Last modification date: 2024-03-13)

• Primary citation: Howes, S.C.,Geyer, E.A.,LaFrance, B.,Zhang, R.,Kellogg, E.H.,Westermann, S.,Rice, L.M.,Nogales, E.; Structural differences between yeast and mammalian microtubules revealed by cryo-EM.; J. Cell Biol., 216:2669-2677, 2017; PubMed: 28652389; DOI: 10.1083/jcb.201612195

Experimental method

ELECTRON MICROSCOPY (4 Å)