7PWO
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![BU of 7pwo by Molmil](/molmil-images/mine/7pwo) | Cryo-EM structure of Giardia lamblia ribosome at 2.75 A resolution | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S26, 40S ribosomal protein S30, ... | Authors: | Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A. | Deposit date: | 2021-10-07 | Release date: | 2022-04-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia. Nucleic Acids Res., 50, 2022
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7PZY
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![BU of 7pzy by Molmil](/molmil-images/mine/7pzy) | Structure of the vacant Candida albicans 80S ribosome | Descriptor: | 1,4-DIAMINOBUTANE, 18S ribosomal RNA, 25S ribosomal RNA, ... | Authors: | Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | Deposit date: | 2021-10-13 | Release date: | 2022-05-18 | Last modified: | 2022-06-08 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
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7Q0P
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![BU of 7q0p by Molmil](/molmil-images/mine/7q0p) | Structure of the Candida albicans 80S ribosome in complex with anisomycin | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | Authors: | Kolosova, O, Zgadzay, Y, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | Deposit date: | 2021-10-15 | Release date: | 2022-05-18 | Last modified: | 2022-06-08 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
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7Q0F
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![BU of 7q0f by Molmil](/molmil-images/mine/7q0f) | Structure of Candida albicans 80S ribosome in complex with phyllanthoside | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | Authors: | Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | Deposit date: | 2021-10-14 | Release date: | 2022-05-18 | Last modified: | 2022-06-08 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
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7PIC
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![BU of 7pic by Molmil](/molmil-images/mine/7pic) | 70S ribosome with P/E-site tRNA in spectinomycin-treated Mycoplasma pneumoniae cells | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | Deposit date: | 2021-08-19 | Release date: | 2022-05-25 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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7PI8
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![BU of 7pi8 by Molmil](/molmil-images/mine/7pi8) | 70S ribosome with P-site tRNA in spectinomycin-treated Mycoplasma pneumoniae cells | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | Deposit date: | 2021-08-19 | Release date: | 2022-05-25 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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7PIA
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![BU of 7pia by Molmil](/molmil-images/mine/7pia) | 70S ribosome with A/P- and P/E-site tRNAs in spectinomycin-treated Mycoplasma pneumoniae cells | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | Deposit date: | 2021-08-19 | Release date: | 2022-05-25 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (13.6 Å) | Cite: | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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7PIQ
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![BU of 7piq by Molmil](/molmil-images/mine/7piq) | 70S ribosome with A- and P-site tRNAs in pseudouridimycin-treated Mycoplasma pneumoniae cells | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | Deposit date: | 2021-08-23 | Release date: | 2022-05-25 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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8EIU
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![BU of 8eiu by Molmil](/molmil-images/mine/8eiu) | E. coli 70S ribosome with A-loop mutations U2554C and U2555C | Descriptor: | 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | Authors: | Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D. | Deposit date: | 2022-09-15 | Release date: | 2023-02-01 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.24 Å) | Cite: | Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome. Nucleic Acids Res., 51, 2023
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8EMM
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![BU of 8emm by Molmil](/molmil-images/mine/8emm) | |
8EV7
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![BU of 8ev7 by Molmil](/molmil-images/mine/8ev7) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with kanamycin, mRNA, and A-, P-, and E-site tRNAs | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Seely, S.M, Gagnon, M.G. | Deposit date: | 2022-10-19 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
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8EVR
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![BU of 8evr by Molmil](/molmil-images/mine/8evr) | Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II | Descriptor: | (1S,3S,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-alpha-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)decahydro-1,4-methano-s-indacene-3a(1H)-carboxylate, 18S rRNA, 25S rRNA, ... | Authors: | Zhao, Y, Rai, J, Li, H. | Deposit date: | 2022-10-20 | Release date: | 2023-09-06 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8EVS
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![BU of 8evs by Molmil](/molmil-images/mine/8evs) | Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure II | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Zhao, Y, Rai, J, Li, H. | Deposit date: | 2022-10-20 | Release date: | 2023-09-06 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8EYT
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![BU of 8eyt by Molmil](/molmil-images/mine/8eyt) | 30S_delta_ksgA+KsgA complex | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Sun, J, Kinman, L.F, Jahagirdar, D, Ortega, J, Davis, J.H. | Deposit date: | 2022-10-28 | Release date: | 2023-09-06 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | KsgA facilitates ribosomal small subunit maturation by proofreading a key structural lesion. Nat.Struct.Mol.Biol., 30, 2023
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8EWB
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![BU of 8ewb by Molmil](/molmil-images/mine/8ewb) | Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure III | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Zhao, Y, Rai, J, Li, H. | Deposit date: | 2022-10-22 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8EVT
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![BU of 8evt by Molmil](/molmil-images/mine/8evt) | Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) refined against a composite map | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Zhao, Y, Rai, J, Li, H. | Deposit date: | 2022-10-20 | Release date: | 2023-09-06 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8FR8
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![BU of 8fr8 by Molmil](/molmil-images/mine/8fr8) | Structure of Mycobacterium smegmatis Rsh bound to a 70S translation initiation complex | Descriptor: | 16S rRNA (1511-MER), 23S rRNA (3119-MER), 30S ribosomal protein S10, ... | Authors: | Majumdar, S, Sharma, M.R, Manjari, S.R, Banavali, N.K, Agrawal, R.K. | Deposit date: | 2023-01-06 | Release date: | 2023-05-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8FC6
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![BU of 8fc6 by Molmil](/molmil-images/mine/8fc6) | Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.35A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. | Deposit date: | 2022-12-01 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
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8FTO
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![BU of 8fto by Molmil](/molmil-images/mine/8fto) | |
8G2D
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![BU of 8g2d by Molmil](/molmil-images/mine/8g2d) | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with tylosin, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.70A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. | Deposit date: | 2023-02-03 | Release date: | 2023-12-27 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 20, 2024
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8G2C
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![BU of 8g2c by Molmil](/molmil-images/mine/8g2c) | Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with tylosin, mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.65A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. | Deposit date: | 2023-02-03 | Release date: | 2023-12-27 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 20, 2024
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8FVY
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![BU of 8fvy by Molmil](/molmil-images/mine/8fvy) | 40S subunit of the Giardia lamblia 80S ribosome | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ... | Authors: | Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. | Deposit date: | 2023-01-20 | Release date: | 2024-01-24 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
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8G6W
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![BU of 8g6w by Molmil](/molmil-images/mine/8g6w) | |
8GLP
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![BU of 8glp by Molmil](/molmil-images/mine/8glp) | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-03-22 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8G61
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![BU of 8g61 by Molmil](/molmil-images/mine/8g61) | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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