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5CCV
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BU of 5ccv by Molmil
Crystal structure of full-length NS5 from dengue virus type 3
Descriptor: RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Klema, V.J, Choi, K.H.
Deposit date:2015-07-02
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface.
Plos Pathog., 12, 2016
8AZA
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BU of 8aza by Molmil
Structure of RIP2K dimer bound to the XIAP BIR2 domain
Descriptor: E3 ubiquitin-protein ligase XIAP, Receptor-interacting serine/threonine-protein kinase 2, ZINC ION
Authors:Pellegrini, E, Cusack, S.
Deposit date:2022-09-05
Release date:2022-10-26
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface.
Life Sci Alliance, 6, 2023
6AO7
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BU of 6ao7 by Molmil
Crystal Structure of a GNAT family acetyltransferase from Elizabethkingia anophelis with acetyl-CoA bound
Descriptor: ACETYL COENZYME *A, Acetyltransferase, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-08-15
Release date:2017-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural characterization of a GNAT family acetyltransferase from Elizabethkingia anophelis bound to acetyl-CoA reveals a new dimeric interface.
Sci Rep, 11, 2021
2PGZ
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BU of 2pgz by Molmil
Crystal structure of Cocaine bound to an ACh-Binding Protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COCAINE, Soluble acetylcholine receptor, ...
Authors:Hansen, S.B, Taylor, P.
Deposit date:2007-04-10
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.
J.Mol.Biol., 369, 2007
4D79
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BU of 4d79 by Molmil
Crystal structure of E. coli tRNA N6-threonylcarbamoyladenosine dehydratase, TcdA, in complex with ATP at 1.768 Angstroem resolution
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, POTASSIUM ION, ...
Authors:Lopez-Estepa, M, Arda, A, Savko, M, Round, A, Shepard, W, Bruix, M, Coll, M, Fernandez, F.J, Jimenez-Barbero, J, Vega, M.C.
Deposit date:2014-11-21
Release date:2015-05-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.768 Å)
Cite:The Crystal Structure and Small-Angle X-Ray Analysis of Csdl/Tcda Reveal a New tRNA Binding Motif in the Moeb/E1 Superfamily.
Plos One, 10, 2015
4D7A
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BU of 4d7a by Molmil
Crystal structure of E. coli tRNA N6-threonylcarbamoyladenosine dehydratase, TcdA, in complex with AMP at 1.801 Angstroem resolution
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCEROL, PHOSPHATE ION, ...
Authors:Lopez-Estepa, M, Arda, A, Savko, M, Round, A, Shepard, W, Bruix, M, Coll, M, Fernandez, F.J, Jimenez-Barbero, J, Vega, M.C.
Deposit date:2014-11-21
Release date:2015-05-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:The Crystal Structure and Small-Angle X-Ray Analysis of Csdl/Tcda Reveal a New tRNA Binding Motif in the Moeb/E1 Superfamily.
Plos One, 10, 2015
2PH9
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BU of 2ph9 by Molmil
Galanthamine bound to an ACh-binding Protein
Descriptor: (-)-GALANTHAMINE, Soluble acetylcholine receptor, TETRAETHYLENE GLYCOL
Authors:Hansen, S.B, Taylor, P.
Deposit date:2007-04-10
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.
J.Mol.Biol., 369, 2007
6G8O
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BU of 6g8o by Molmil
Solution structure of the cross-linked SAM domain dimer of murine SLy1
Descriptor: SAM and SH3 domain-containing protein 3
Authors:Kukuk, L.K, Dingley, A.J, Koenig, B.W.
Deposit date:2018-04-09
Release date:2019-01-30
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association.
Sci Rep, 9, 2019
6GOA
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BU of 6goa by Molmil
Structural basis for OXA-48 dimerization - R189A mutant
Descriptor: Beta-lactamase, CHLORIDE ION
Authors:Lund, B.A, Thomassen, A.M, Leiros, H.K.S.
Deposit date:2018-06-01
Release date:2018-07-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.
FEBS J., 285, 2018
4EHX
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BU of 4ehx by Molmil
Crystal structure of LpxK from Aquifex aeolicus at 1.9 angstrom resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H.
Deposit date:2012-04-04
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface.
Proc.Natl.Acad.Sci.USA, 109, 2012
6V5A
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BU of 6v5a by Molmil
Crystal structure of the human BK channel gating ring L390P mutant
Descriptor: CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, SULFATE ION
Authors:Deng, Z, Yuan, P.
Deposit date:2019-12-03
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Coupling of Ca2+and voltage activation in BK channels through the alpha B helix/voltage sensor interface.
Proc.Natl.Acad.Sci.USA, 117, 2020
4EHY
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BU of 4ehy by Molmil
Crystal structure of LpxK from Aquifex aeolicus in complex with ADP/Mg2+ at 2.2 angstrom resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
Authors:Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H.
Deposit date:2012-04-04
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EHW
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BU of 4ehw by Molmil
Crystal structure of LpxK from Aquifex aeolicus at 2.3 angstrom resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, Tetraacyldisaccharide 4'-kinase
Authors:Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H.
Deposit date:2012-04-04
Release date:2012-08-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface.
Proc.Natl.Acad.Sci.USA, 109, 2012
3C4P
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BU of 3c4p by Molmil
Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M complex
Descriptor: Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION
Authors:Reynolds, K.A, Hanes, M.S, Thomson, J.M, Antczak, A.J, Berger, J.M, Bonomo, R.A, Kirsch, J.F, Handel, T.M.
Deposit date:2008-01-30
Release date:2008-05-27
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
3BPB
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BU of 3bpb by Molmil
Crystal structure of the dimethylarginine dimethylaminohydrolase H162G adduct with S-methyl-L-thiocitrulline
Descriptor: N~5~-[(E)-imino(methylsulfanyl)methyl]-L-ornithine, dimethylarginine dimethylaminohydrolase
Authors:Monzingo, A.F, Linsky, T.W, Stone, E.M, Fast, W, Robertus, J.D.
Deposit date:2007-12-18
Release date:2008-06-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Promiscuous partitioning of a covalent intermediate common in the pentein superfamily.
Chem.Biol., 15, 2008
8R4I
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BU of 8r4i by Molmil
Cryo-EM structure of human islet amyloid polypeptide (hIAPP)
Descriptor: Islet amyloid polypeptide
Authors:Ooi, S.A, Valli, D, Maj, M.
Deposit date:2023-11-13
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.01 Å)
Cite:Improving cryo-EM grids for amyloid fibrils using interface-active solutions and spectator proteins.
Biophys.J., 123, 2024
6JBM
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BU of 6jbm by Molmil
Crystal structure of the TRIM14 PRYSPRY domain
Descriptor: SULFATE ION, Tripartite motif-containing protein 14
Authors:Yin, Y.X, Yu, Y, Liang, L.
Deposit date:2019-01-26
Release date:2020-03-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The TRIM14 PRYSPRY domain mediates protein interaction via its basic interface.
Febs Lett., 593, 2019
7NND
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BU of 7nnd by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 09
Descriptor: 14-3-3 protein sigma, 5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
Authors:Centorrino, F, Ottmann, C.
Deposit date:2021-02-24
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NMX
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BU of 7nmx by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 12
Descriptor: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), CALCIUM ION, ...
Authors:Centorrino, F, Ottmann, C.
Deposit date:2021-02-23
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NPG
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BU of 7npg by Molmil
Crystal structure of 14-3-3 sigma in complex with 20mer Amot-p130 peptide and fragment 22
Descriptor: 14-3-3 protein sigma, 5-[3-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
Authors:Centorrino, F, Ottmann, C.
Deposit date:2021-02-26
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NMW
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BU of 7nmw by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 40
Descriptor: 14-3-3 protein sigma, 5-(2-azanylethyl)-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
Authors:Centorrino, F, Ottmann, C.
Deposit date:2021-02-23
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NNE
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BU of 7nne by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 22
Descriptor: 14-3-3 protein sigma, 5-[3-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
Authors:Centorrino, F, Ottmann, C.
Deposit date:2021-02-24
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NPB
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BU of 7npb by Molmil
Crystal structure of 14-3-3 sigma in complex with 20mer Amot-p130 peptide and fragment 09
Descriptor: 14-3-3 protein sigma, 5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
Authors:Centorrino, F, Ottmann, C.
Deposit date:2021-02-26
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NMA
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BU of 7nma by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide
Descriptor: 14-3-3 protein sigma, Amot-p130 phosphopeptide (pS175), CHLORIDE ION, ...
Authors:Centorrino, F, Ottmann, C.
Deposit date:2021-02-23
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022
7NN2
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BU of 7nn2 by Molmil
Crystal structure of 14-3-3 sigma in complex with 13mer Amot-p130 peptide and fragment 41
Descriptor: 14-3-3 protein sigma, 7-(6-azanyl-5-methyl-pyridin-2-yl)-1-benzothiophene-2-carboximidamide, Amot-p130 phosphopeptide (pS175), ...
Authors:Centorrino, F, Ottmann, C.
Deposit date:2021-02-24
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Fragment-based exploration of the 14-3-3/Amot-p130 interface.
Curr Res Struct Biol, 4, 2022

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数据于2024-08-07公开中

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