8R4I

Cryo-EM structure of human islet amyloid polypeptide (hIAPP)

Summary for 8R4I

Entry DOI	10.2210/pdb8r4i/pdb
EMDB information	18887
Descriptor	Islet amyloid polypeptide (1 entity in total)
Functional Keywords	amyloid, fibril, protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	10
Total formula weight	39073.12
Authors	Ooi, S.A.,Valli, D.,Maj, M. (deposition date: 2023-11-13, release date: 2024-03-06, Last modification date: 2024-03-27)
Primary citation	Valli, D.,Ooi, S.A.,Scattolini, G.,Chaudhary, H.,Tietze, A.A.,Maj, M. Improving cryo-EM grids for amyloid fibrils using interface-active solutions and spectator proteins. Biophys.J., 123:718-729, 2024 Cited by PubMed: 38368506 DOI: 10.1016/j.bpj.2024.02.009 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.01 Å)

Structure validation