PDB: 491 resultsInfo pagesStatus searchChemie searchBIRD

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3TJ3	Structure of importin a5 bound to the N-terminus of Nup50 Descriptor: Importin subunit alpha-1, Nuclear pore complex protein Nup50 Authors: Pumroy, R, Nardozzi, J.D, Hart, D.J, Root, M.J, Cingolani, G. Deposit date: 2011-08-23 Release date: 2011-11-30 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.702 Å) Cite: Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha 5. J.Biol.Chem., 287, 2012
3UL0	Mouse importin alpha: mouse CBP80Y8D cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3UKY	Mouse importin alpha: yeast CBP80 cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein complex subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3UKZ	Mouse importin alpha: mouse CBP80 cNLS complex Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 Authors: Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. Deposit date: 2011-11-10 Release date: 2012-10-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
3RZX	Mouse importin alpha-Ku70 NLS peptide complex Descriptor: Importin subunit alpha-2, Ku70 NLS peptide Authors: Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2011-05-12 Release date: 2011-08-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80. J.Mol.Biol., 412, 2011
8Q8K	KI Polyomavirus LTA NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Large T antigen Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-18 Release date: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8HKW	Crystal structure of importin-alpha3 bound to the 53BP1 nuclear localization signal Descriptor: Importin subunit alpha-3, Peptide from TP53-binding protein 1 Authors: Matsuura, Y. Deposit date: 2022-11-28 Release date: 2022-12-21 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystallographic data of an importin-alpha 3 dimer in which the two protomers are bridged by a bipartite nuclear localization signal. Data Brief, 47, 2023
8SUD	JC Polyomavirus LTA NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Large T antigen Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-05-12 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUU	MW Polyomavirus LTA bipartite NLS bound to importin alpha 2 Descriptor: Importin subunit alpha-1, Large T-antigen Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-17 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
8TUT	Merkel Cell Polyomavirus LTA NLSct bound to importin alpha 2 Descriptor: Importin subunit alpha-1, PRO-PRO-LYS-PRO-LYS-LYS-ASN-ARG-GLU Authors: Cross, E.M, Forwood, J.K, Alvisi, G. Deposit date: 2023-08-17 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.55 Å) Cite: A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
5XZX	Crystal structure of importin-alpha3 bound to the nuclear localization signal of Ran-binding protein 3 Descriptor: Importin subunit alpha-3, Ran-binding protein 3 Authors: Koyama, M, Matsuura, Y. Deposit date: 2017-07-14 Release date: 2017-08-09 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of importin-alpha 3 bound to the nuclear localization signal of Ran-binding protein 3 Biochem. Biophys. Res. Commun., 491, 2017
3RZ9	Mouse importin alpha-Ku80 NLS peptide complex Descriptor: Importin subunit alpha-2, Ku80 NLS peptide Authors: Barros, A.C, Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2011-05-11 Release date: 2011-08-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80. J.Mol.Biol., 412, 2011
5B56	Crystal structure of HIV-1 VPR C-Terminal domain and DIBB-M-Importin-Alpha2 complex Descriptor: Importin subunit alpha-1, Protein Vpr Authors: Miyatake, H, Sanjoh, A, Matusda, G, Murakami, T, Murakami, H, Hagiwara, K, Yokoyama, M, Sato, H, Miyamoto, Y, Dohmae, N, Aida, Y. Deposit date: 2016-04-25 Release date: 2016-06-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Molecular Mechanism of HIV-1 Vpr for Binding to Importin-alpha J.Mol.Biol., 428, 2016
4RXH	Crystal Structure of Importin-alpha from Neurospora crassa complexed with SV40NLS Descriptor: Importin subunit alpha, Large T antigen Authors: Bernardes, N.E, Takeda, A.A.S, Fontes, M.R.M. Deposit date: 2014-12-11 Release date: 2015-07-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7553 Å) Cite: Structure of Importin-alpha from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal. Plos One, 10, 2015
5TBK	Crystal structure of human importin a3 bound to RCC1 Descriptor: Importin subunit alpha-3, Regulator of chromosome condensation Authors: Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G. Deposit date: 2016-09-12 Release date: 2017-09-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1. Nat Commun, 8, 2017
8FK3	Adeno-Associated Virus Porcine Origin capsid protein basic regions in complex with Importin-alpha 2 Descriptor: Importin subunit alpha-1, VP1 Authors: Hoad, M, Forwood, J.K, Roby, J.A. Deposit date: 2022-12-20 Release date: 2023-03-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural Characterization of Porcine Adeno-Associated Virus Capsid Protein with Nuclear Trafficking Protein Importin Alpha Reveals a Bipartite Nuclear Localization Signal. Viruses, 15, 2023
5V5O	Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha Descriptor: Importin subunit alpha-1, Nucleoprotein Authors: Sankhala, R.S, Lokareddy, R.K, Cingolani, G. Deposit date: 2017-03-14 Release date: 2018-03-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.243 Å) Cite: Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms. Sci Rep, 7, 2017
5V5P	Structure of NLS2R of influenza A virus nucleoprotein bound to importin alpha Descriptor: Importin subunit alpha-1, Nucleoprotein Authors: Sankhala, R.S, Lokareddy, R.K, Cingolani, G. Deposit date: 2017-03-14 Release date: 2018-03-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms. Sci Rep, 7, 2017
3W5K	Crystal structure of Snail1 and importin beta complex Descriptor: Importin subunit beta-1, ZINC ION, Zinc finger protein SNAI1 Authors: Choi, S, Yamashita, E, Yasuhara, N, Song, J, Son, S.Y, Won, Y.H, Shin, Y.S, Sekimoto, T, Park, I.Y, Yoneda, Y, Lee, S.J. Deposit date: 2013-01-30 Release date: 2014-03-05 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta. Acta Crystallogr.,Sect.D, 70, 2014
5VQI	Nuclear transport of the Neurospora crassa NIT2 transcription factor is mediated by Importin-alpha Descriptor: Importin subunit alpha, Nuclear localization sequence of NIT2 transcription factor (NIT2-NLS) Authors: Bernardes, N.E, Fontes, M.R.M. Deposit date: 2017-05-09 Release date: 2017-11-01 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.501 Å) Cite: Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by importin-alpha. Biochem. J., 474, 2017
4B18	The crystal structure of human Importin alpha 5 with TERT NLS peptide Descriptor: IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE TRANSCRIPTASE Authors: Kim, K.L, Yoo, J.H, Cho, H.S. Deposit date: 2012-07-08 Release date: 2013-09-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Akt-Mediated Phosphorylation Increases the Binding Affinity of Htert for Importin Alpha to Promote Nuclear Translocation. J.Cell.Sci., 128, 2015
5SVZ	HIV-1 Tat NLS in complex with importin alpha Descriptor: Importin subunit alpha-1, Tat Authors: Smith, K.M, Himiari, Z, Forwood, J.K. Deposit date: 2016-08-08 Release date: 2016-08-31 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Basis for Importin-alpha Binding of the Human Immunodeficiency Virus Tat. Sci Rep, 7, 2017
7LF4	Structure of importin a3 bound to the p50- and p65-NLSs Descriptor: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65 Authors: Florio, T.J, Lokareddy, R.K, Cingolani, G. Deposit date: 2021-01-15 Release date: 2022-01-19 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13, 2022
7LET	Structure of importin a2 bound to the p50- and p65-NLSs Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65 Authors: Florio, T.J, Lokareddy, R.K, Cingolani, G. Deposit date: 2021-01-15 Release date: 2022-01-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13, 2022
7LFC	Structure of importin a3 bound to p50 NLS Descriptor: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit Authors: Florio, T.J, Lokareddy, R.K, Cingolani, G. Deposit date: 2021-01-16 Release date: 2022-01-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13, 2022

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