6EYP
 
 | | X-ray structure of the unliganded uridine phosphorylase from Vibrio cholerae at 1.22A | | Descriptor: | GLYCEROL, MAGNESIUM ION, SODIUM ION, ... | | Authors: | Prokofev, I.I, Balaev, V.V, Gabdoulkhakov, A.G, Betzel, C, Lashkov, A.A. | | Deposit date: | 2017-11-13 | | Release date: | 2018-11-21 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.22 Å) | | Cite: | X-ray structure of the unliganded uridine phosphorylase from Vibrio cholerae at 1.22A
To Be Published
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5UXH
 | | Structure of Human POFUT1 in complex with GDP-fucose | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP-fucose protein O-fucosyltransferase 1, GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE | | Authors: | Xu, X, McMillan, B, Blacklow, S.C. | | Deposit date: | 2017-02-22 | | Release date: | 2017-04-05 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations.
Glycobiology, 27, 2017
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7T11
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5OHA
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with 2-Thiohydantoin | | Descriptor: | 2-sulfanylideneimidazol-4-one, Cereblon isoform 4, ZINC ION | | Authors: | Boichenko, I, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | | Deposit date: | 2017-07-14 | | Release date: | 2018-10-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Chemical Ligand Space of Cereblon.
Acs Omega, 3, 2018
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3L1Y
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5OH3
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Ethosuximide | | Descriptor: | (3~{S})-3-ethyl-3-methyl-pyrrolidine-2,5-dione, Cereblon isoform 4, ZINC ION | | Authors: | Boichenko, I, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | | Deposit date: | 2017-07-14 | | Release date: | 2018-10-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Chemical Ligand Space of Cereblon.
Acs Omega, 3, 2018
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5OH7
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Imidazolidine-2,4-dione (Hydantoin) | | Descriptor: | Cereblon isoform 4, ZINC ION, imidazolidine-2,4-dione | | Authors: | Boichenko, I, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | | Deposit date: | 2017-07-14 | | Release date: | 2018-10-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Chemical Ligand Space of Cereblon.
Acs Omega, 3, 2018
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6TQB
 | | X-ray structure of Roquin ROQ domain in complex with a UCP3 CDE1 SL RNA motif | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Binas, O, Tants, J.-N, Peter, S.A, Janowski, R, Davydova, E, Braun, J, Niessing, D, Schwalbe, H, Weigand, J.E, Schlundt, A. | | Deposit date: | 2019-12-16 | | Release date: | 2020-05-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for the recognition of transiently structured AU-rich elements by Roquin.
Nucleic Acids Res., 48, 2020
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6DB1
 | | 2.0 Angstrom Resolution Crystal Structure of N-Terminal Ligand-Binding Domain of Putative Methyl-Accepting Chemotaxis Protein from Salmonella enterica | | Descriptor: | CHLORIDE ION, Putative methyl-accepting chemotaxis protein | | Authors: | Minasov, G, Shuvalova, L, Dubrovska, I, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2018-05-02 | | Release date: | 2018-05-16 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | 2.0 Angstrom Resolution Crystal Structure of N-Terminal Ligand-Binding Domain of Putative Methyl-Accepting Chemotaxis Protein from Salmonella enterica.
To Be Published
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9CR8
 | | SapNP reconstituted human ABCB1 | | Descriptor: | ATP-dependent translocase ABCB1, UNKNOWN BRANCHED FRAGMENT OF PHOSPHOLIPID | | Authors: | Kurre, D, Alam, A. | | Deposit date: | 2024-07-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural insights into binding-site access and ligand recognition by human ABCB1.
Embo J., 44, 2025
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1E0D
 | | UDP-N-Acetylmuramoyl-L-Alanine:D-Glutamate Ligase | | Descriptor: | SULFATE ION, UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE | | Authors: | Fanchon, E, Bertrand, J, Chantalat, L, Dideberg, O. | | Deposit date: | 2000-03-24 | | Release date: | 2000-06-09 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | "Open" Structures of Murd: Domain Movements and Structural Similarities with Folylpolyglutamate Synthetase.
J.Mol.Biol., 301, 2000
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1E0O
 | | CRYSTAL STRUCTURE OF A TERNARY FGF1-FGFR2-HEPARIN COMPLEX | | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, FIBROBLAST GROWTH FACTOR 1, FIBROBLAST GROWTH FACTOR RECEPTOR 2, ... | | Authors: | Pellegrini, L, Burke, D.F, von Delft, F, Mulloy, B, Blundell, T.L. | | Deposit date: | 2000-04-03 | | Release date: | 2000-10-23 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of Fibroblast Growth Factor Receptor Ectodomain Bound to Ligand and Heparin
Nature, 407, 2000
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9CTG
 | | SapNP Reconstituted Human ABCB1 bound to ATP gammaS | | Descriptor: | ATP-dependent translocase ABCB1, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Kurre, D, Alam, A. | | Deposit date: | 2024-07-25 | | Release date: | 2025-01-22 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural insights into binding-site access and ligand recognition by human ABCB1.
Embo J., 44, 2025
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9CTC
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9CTF
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4BDL
 | | Crystal structure of the GluK2 K531A LBD dimer in complex with glutamate | | Descriptor: | GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2, GLUTAMIC ACID, ... | | Authors: | Nayeem, N, Mayans, O, Green, T. | | Deposit date: | 2012-10-05 | | Release date: | 2013-04-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
Open Biol., 3, 2013
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9NGC
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6G3C
 | | Crystal Structure of JAK2-V617F pseudokinase domain in complex with Compound 2 | | Descriptor: | 1,2-ETHANEDIOL, 2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7,7-trimethyl-8-(3-methylbutyl)pteridin-6-one, Tyrosine-protein kinase | | Authors: | Dekker, C, Hinniger, A. | | Deposit date: | 2018-03-24 | | Release date: | 2019-03-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Discovery and Structural Characterization of ATP-Site Ligands for the Wild-Type and V617F Mutant JAK2 Pseudokinase Domain.
Acs Chem.Biol., 14, 2019
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7CT6
 | | Crystal structure of GCL from Deinococcus metallilatus | | Descriptor: | Glyoxylate carboligase | | Authors: | Kim, J.H, Kim, J.S. | | Deposit date: | 2020-08-18 | | Release date: | 2021-08-25 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Glyoxylate carboligase-based whole-cell biotransformation of formaldehyde into ethylene glycol via glycolaldehyde.
Green Chem, 1, 2022
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7CYA
 | | Saimiri boliviensis boliviensis galectin-13 with lactose | | Descriptor: | Galectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Su, J. | | Deposit date: | 2020-09-03 | | Release date: | 2021-06-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Actin binding to galectin-13/placental protein-13 occurs independently of the galectin canonical ligand-binding site.
Glycobiology, 31, 2021
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7CYB
 | | Saimiri boliviensis boliviensis galectin-13 with glycerol | | Descriptor: | GLYCEROL, Galectin | | Authors: | Su, J. | | Deposit date: | 2020-09-03 | | Release date: | 2021-06-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Actin binding to galectin-13/placental protein-13 occurs independently of the galectin canonical ligand-binding site.
Glycobiology, 31, 2021
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5NNI
 | | Dimer structure of Sortilin ectodomain crystal form 2, 3.2 Angstrom | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sortilin, ... | | Authors: | Leloup, N.O.L, Janssen, B.J.C. | | Deposit date: | 2017-04-09 | | Release date: | 2017-11-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.21 Å) | | Cite: | Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.
Nat Commun, 8, 2017
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4J8T
 | | Engineered Digoxigenin binder DIG10.2 | | Descriptor: | DIGOXIGENIN, Engineered Digoxigenin binder protein DIG10.2 | | Authors: | Stoddard, B.L, Doyle, L.A. | | Deposit date: | 2013-02-14 | | Release date: | 2013-06-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Computational design of ligand-binding proteins with high affinity and selectivity.
Nature, 501, 2013
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6QF1
 | | X-Ray structure of Proteinase K crystallized on a silicon chip | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Proteinase K | | Authors: | Lieske, J, Cerv, M, Kreida, S, Barthelmess, M, Fischer, P, Pakendorf, T, Yefanov, O, Mariani, V, Seine, T, Ross, B.H, Crosas, E, Lorbeer, O, Burkhardt, A, Lane, T.J, Guenther, S, Bergtholdt, J, Schoen, S, Tornroth-Horsefield, S, Chapman, H.N, Meents, A. | | Deposit date: | 2019-01-09 | | Release date: | 2019-07-10 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.737 Å) | | Cite: | On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies.
Iucrj, 6, 2019
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5OHB
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Piperidin-2-one (Valerolactam) | | Descriptor: | Cereblon isoform 4, ZINC ION, piperidin-2-one | | Authors: | Boichenko, I, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | | Deposit date: | 2017-07-14 | | Release date: | 2018-10-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Chemical Ligand Space of Cereblon.
Acs Omega, 3, 2018
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