6TQB

X-ray structure of Roquin ROQ domain in complex with a UCP3 CDE1 SL RNA motif

Summary for 6TQB

• Entry DOI: 10.2210/pdb6tqb/pdb
• Descriptor: Roquin-1, RNA (5'-R(P*GP*GP*AP*AP*AP*UP*UP*AP*UP*AP*UP*UP*AP*AP*UP*UP*UP*CP*C)-3'), 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: roquin, roq domain, rna binding, ucp1, rna binding protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 27051.74

Authors

Binas, O.,Tants, J.-N.,Peter, S.A.,Janowski, R.,Davydova, E.,Braun, J.,Niessing, D.,Schwalbe, H.,Weigand, J.E.,Schlundt, A. (deposition date: 2019-12-16, release date: 2020-05-27, Last modification date: 2024-01-24)

• Primary citation: Binas, O.,Tants, J.N.,Peter, S.A.,Janowski, R.,Davydova, E.,Braun, J.,Niessing, D.,Schwalbe, H.,Weigand, J.E.,Schlundt, A.; Structural basis for the recognition of transiently structured AU-rich elements by Roquin.; Nucleic Acids Res., 48:7385-7403, 2020; PubMed: 32491174; DOI: 10.1093/nar/gkaa465

Experimental method

X-RAY DIFFRACTION (1.6 Å)