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2AC4
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Crystal structure of the His183Cys mutant variant of Bacillus subtilis Ferrochelatase
Descriptor: Ferrochelatase
Authors:Shipovskov, S, Karlberg, T, Fodje, M, Hansson, M.D, Ferreira, G.C, Hansson, M, Reimann, C.T, Al-Karadaghi, S.
Deposit date:2005-07-18
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism.
J.Mol.Biol., 352, 2005
2ACI
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Structure of D166A arginine deiminase
Descriptor: Arginine deiminase
Authors:Galkin, A, Lu, X, Dunaway-Mariano, D, Herzberg, O.
Deposit date:2005-07-18
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures Representing the Michaelis Complex and the Thiouronium Reaction Intermediate of Pseudomonas aeruginosa Arginine Deiminase.
J.Biol.Chem., 280, 2005
1ZTN
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INACTIVATION GATE OF POTASSIUM CHANNEL RAW3, NMR, 8 STRUCTURES
Descriptor: Potassium voltage-gated channel subfamily C member 4
Authors:Antz, C, Geyer, M, Fakler, B, Schott, M, Frank, R, Guy, H.R, Ruppersberg, J.P, Kalbitzer, H.R.
Deposit date:1996-11-15
Release date:1997-06-05
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structure of inactivation gates from mammalian voltage-dependent potassium channels.
Nature, 385, 1997
2AGD
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Crystal Structure of Human M340H-Beta-1,4-Galactosyltransferase-I(M340H-B4Gal-T1) in Complex with GlcNAc-beta1,4-Man-alpha1,3-Man-beta-OR
Descriptor: 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose, ...
Authors:Ramasamy, V, Ramakrishnan, B, Boeggeman, E, Ratner, D.M, Seeberger, P.H, Qasba, P.K.
Deposit date:2005-07-26
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety
J.Mol.Biol., 353, 2005
2QZ8
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Crystal structure of Mycobacterium tuberculosis Leucine response regulatory protein (LrpA)
Descriptor: Probable transcriptional regulatory protein
Authors:Manchi, C.M.R, Gokulan, K, Ioerger, T, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2007-08-16
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of Mycobacterium tuberculosis LrpA, a leucine-responsive global regulator associated with starvation response.
Protein Sci., 17, 2008
2B2C
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BU of 2b2c by Molmil
Cloning, expression, characterisation and three- dimensional structure determination of the Caenorhabditis elegans spermidine synthase
Descriptor: spermidine synthase
Authors:Dufe, V.T, Luersen, K, Eschbach, M.L, Haider, N, Karlberg, T, Walter, R.D, Al-Karadaghi, S.
Deposit date:2005-09-19
Release date:2005-11-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cloning, expression, characterisation and three-dimensional structure determination of Caenorhabditis elegans spermidine synthase
FEBS LETT., 579, 2005
2ATA
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BU of 2ata by Molmil
Structural Basis of DNA Recognition by p53 Tetramers (complex II)
Descriptor: 5'-D(*AP*AP*GP*GP*CP*AP*TP*GP*CP*CP*TP*T)-3', Cellular tumor antigen p53, ZINC ION
Authors:Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z.
Deposit date:2005-08-24
Release date:2006-07-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006
2ARA
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APO FORM OF ESCHERICHIA COLI REGULATORY PROTEIN ARAC
Descriptor: ARAC
Authors:Soisson, S.M, Wolberger, C.
Deposit date:1996-10-30
Release date:1997-05-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for ligand-regulated oligomerization of AraC.
Science, 276, 1997
2AHX
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BU of 2ahx by Molmil
Crystal structure of ErbB4/HER4 extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-4, SULFATE ION, ...
Authors:Bouyain, S, Longo, P.A, Li, S, Ferguson, K.M, Leahy, D.J.
Deposit date:2005-07-28
Release date:2005-09-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand
Proc.Natl.Acad.Sci.USA, 102, 2005
2ANK
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BU of 2ank by Molmil
orally active thrombin inhibitors in complex with thrombin and an exosite decapeptide
Descriptor: N-[(1R)-2-[(1-{[({6-[AMINO(IMINO)METHYL]PYRIDIN-3-YL}METHYL)AMINO]CARBONYL}CYCLOPENTYL)AMINO]-1-(CYCLOHEXYLMETHYL)-2-OXOETHYL]GLYCINE, Thrombin heavy chain, Thrombin light chain, ...
Authors:Lange, U.E.W, Baucke, D, Hornberger, W, Mack, H, Seitz, W, Hoeffken, H.W.
Deposit date:2005-08-11
Release date:2006-11-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Orally active thrombin inhibitors. Part 2: optimization of the P2-moiety
BIOORG.MED.CHEM.LETT., 16, 2006
2AQ3
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Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3
Descriptor: Enterotoxin type C-3, T-cell receptor beta chain V
Authors:Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
Deposit date:2005-08-17
Release date:2006-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2AO7
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Adam10 Disintegrin and cysteine- rich domain
Descriptor: ADAM 10, SULFATE ION
Authors:Janes, P.W, Saha, N, Barton, W.A, Kolev, M.V, Wimmer-Kleikamp, S.H, Nievergall, E, Blobel, C.P, Himanen, J.-P, Lackmann, M, Nikolov, D.B.
Deposit date:2005-08-12
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005
2APB
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Crystal Structure of the S54N variant of murine T cell receptor Vbeta 8.2 domain
Descriptor: MALONIC ACID, T-cell receptor beta chain V
Authors:Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
Deposit date:2005-08-16
Release date:2006-03-21
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APQ
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Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop.
Descriptor: PHOSPHATE ION, Ribonuclease
Authors:Sambashivan, S, Liu, Y, Sawaya, M.R, Gingery, M, Eisenberg, D.
Deposit date:2005-08-16
Release date:2005-09-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure.
Nature, 437, 2005
2APX
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Crystal Structure of the G17E/A52V/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain
Descriptor: MALONIC ACID, T cell receptor beta chain V
Authors:Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
Deposit date:2005-08-16
Release date:2006-03-21
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2AJQ
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Structure of replicative DNA polymerase provides insigts into the mechanisms for processivity, frameshifting and editing
Descriptor: DNA Primer, DNA Template, T7 DNA polymerase, ...
Authors:Brieba, L, Ellenberger, T.
Deposit date:2005-08-02
Release date:2006-09-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of replicative DNA polymerase provides insigts into the mechanisms for processivity, frameshifting and editing
To be Published
2AQX
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Crystal Structure of the Catalytic and CaM-Binding domains of Inositol 1,4,5-Trisphosphate 3-Kinase B
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PREDICTED: inositol 1,4,5-trisphosphate 3-kinase B
Authors:Chamberlain, P.P, Sandberg, M.L, Sauer, K, Cooke, M.P, Lesley, S.A, Spraggon, G.
Deposit date:2005-08-18
Release date:2005-12-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into enzyme regulation for inositol 1,4,5-trisphosphate 3-kinase B
Biochemistry, 44, 2005
2AQ2
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BU of 2aq2 by Molmil
Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant
Descriptor: Enterotoxin type C-3, SODIUM ION, SULFATE ION, ...
Authors:Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
Deposit date:2005-08-17
Release date:2006-03-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
1HX1
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CRYSTAL STRUCTURE OF A BAG DOMAIN IN COMPLEX WITH THE HSC70 ATPASE DOMAIN
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG family molecular chaperone regulator 1, Heat shock 70 kDa protein 8
Authors:Sondermann, H, Scheufler, C, Moarefi, I.
Deposit date:2001-01-11
Release date:2001-03-07
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors.
Science, 291, 2001
1I2T
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X-RAY STRUCTURE OF THE HUMAN HYPERPLASTIC DISCS PROTEIN: AN ORTHOLOG OF THE C-TERMINAL DOMAIN OF POLY(A)-BINDING PROTEIN
Descriptor: HYD PROTEIN
Authors:Deo, R.C, Sonenberg, N, Burley, S.K.
Deposit date:2001-02-12
Release date:2001-04-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding protein.
Proc.Natl.Acad.Sci.USA, 98, 2001
2JWQ
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G-quadruplex recognition by quinacridines: a SAR, NMR and Biological study
Descriptor: DNA (5'-D(*DTP*DTP*DAP*DGP*DGP*DGP*DT)-3'), N,N'-(dibenzo[b,j][1,7]phenanthroline-2,10-diyldimethanediyl)dipropan-1-amine
Authors:Hounsou, C, Guittat, L, Monchaud, D, Jourdan, M, Saettel, N, Mergny, J.L, Teulade-Fichou, M.
Deposit date:2007-10-23
Release date:2008-03-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:G-Quadruplex Recognition by Quinacridines: a SAR, NMR, and Biological Study
ChemMedChem, 2, 2007
1AJ8
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CITRATE SYNTHASE FROM PYROCOCCUS FURIOSUS
Descriptor: CITRATE SYNTHASE, CITRIC ACID, COENZYME A
Authors:Russell, R.J.M, Ferguson, J.M.C, Hough, D.W, Danson, M.J, Taylor, G.L.
Deposit date:1997-05-16
Release date:1997-11-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of citrate synthase from the hyperthermophilic archaeon pyrococcus furiosus at 1.9 A resolution,.
Biochemistry, 36, 1997
2J5Y
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Crystal structure of the GA module from F.magna
Descriptor: PEPTOSTREPTOCOCCAL ALBUMIN-BINDING PROTEIN
Authors:Lejon, S, Cramer, J.F, Nordberg, P.A, Lundqvist, T, Valegard, K.
Deposit date:2006-09-20
Release date:2007-06-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of a Bacterial Albumin-Binding Domain at 1.4A Resolution.
FEBS Lett., 581, 2007
1IK6
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3D structure of the E1beta subunit of pyruvate dehydrogenase from the archeon Pyrobaculum aerophilum
Descriptor: pyruvate dehydrogenase
Authors:Kleiger, G, Perry, J, Eisenberg, D.
Deposit date:2001-05-02
Release date:2001-12-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:3D structure and significance of the GPhiXXG helix packing motif in tetramers of the E1beta subunit of pyruvate dehydrogenase from the archeon Pyrobaculum aerophilum.
Biochemistry, 40, 2001
1A6L
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T14C MUTANT OF AZOTOBACTER VINELANDII FDI
Descriptor: FE3-S4 CLUSTER, FERREDOXIN, IRON/SULFUR CLUSTER
Authors:Gao-Sheridan, H.S, Kemper, M.A, Khayat, R, Armstrong, F.A, Prasad, G.S, Sridhar, V, Stout, C.D, Burgess, B.K.
Deposit date:1998-02-26
Release date:1998-05-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A T14C variant of Azotobacter vinelandii ferredoxin I undergoes facile [3Fe-4S]0 to [4Fe-4S]2+ conversion in vitro but not in vivo.
J.Biol.Chem., 273, 1998

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数据于2024-07-17公开中

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