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2APX

Crystal Structure of the G17E/A52V/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain

Summary for 2APX
Entry DOI10.2210/pdb2apx/pdb
Related2APB 2APF 2APT 2APV 2APW 2AQ1 2AQ2 2AQ3
DescriptorT cell receptor beta chain V, MALONIC ACID (3 entities in total)
Functional Keywordsthe murine t cell receptor v beta 8.2 domain, immune system
Biological sourceRattus norvegicus (Norway rat)
Total number of polymer chains1
Total formula weight12392.61
Authors
Cho, S.,Swaminathan, C.P.,Yang, J.,Kerzic, M.C.,Guan, R.,Kieke, M.C.,Kranz, D.M.,Mariuzza, R.A.,Sundberg, E.J. (deposition date: 2005-08-16, release date: 2006-03-21, Last modification date: 2018-04-04)
Primary citationCho, S.,Swaminathan, C.P.,Yang, J.,Kerzic, M.C.,Guan, R.,Kieke, M.C.,Kranz, D.M.,Mariuzza, R.A.,Sundberg, E.J.
Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13:1775-1787, 2005
Cited by
PubMed: 16338399
DOI: 10.1016/j.str.2005.08.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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