8B5P
 
 | |
8BI7
 | | Binary structure of 14-3-3s and PKR phosphopeptide | | Descriptor: | 14-3-3 protein sigma, MAGNESIUM ION, PKR phosphopeptide | | Authors: | Somsen, B.A, Ottmann, C. | | Deposit date: | 2022-11-01 | | Release date: | 2023-03-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.
J.Am.Chem.Soc., 145, 2023
|
|
8SMU
 | | Integral fusion of the HtaA CR2 domain from Corynebacterium diphtheriae within EGFP | | Descriptor: | CHLORIDE ION, GLYCEROL, HtaACR2 integral fusion within enhanced green fluorescent protein, ... | | Authors: | Mahoney, B.J, Cascio, D, Clubb, R.T. | | Deposit date: | 2023-04-26 | | Release date: | 2023-09-27 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Development and atomic structure of a new fluorescence-based sensor to probe heme transfer in bacterial pathogens.
J.Inorg.Biochem., 249, 2023
|
|
8BFC
 | | Binary structure of 14-3-3s and RND3 phosphopeptide | | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Somsen, B.A, Ottmann, C. | | Deposit date: | 2022-10-24 | | Release date: | 2023-03-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach.
J.Am.Chem.Soc., 145, 2023
|
|
4ZKY
 | | Structure of F420 binding protein, MSMEG_6526, from Mycobacterium smegmatis | | Descriptor: | CHLORIDE ION, IODIDE ION, Pyridoxamine 5-phosphate oxidase, ... | | Authors: | Lee, B.M, Carr, P.D, Ahmed, F.H, Jackson, C.J. | | Deposit date: | 2015-05-01 | | Release date: | 2015-10-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria.
J.Mol.Biol., 427, 2015
|
|
8BE7
 | |
8BO2
 | | BAM-EspP complex structure with BamA-S425C/EspP-S1299C mutations in nanodisc | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Shen, C, Chang, S, Luo, Q, Zhang, Z, Xie, T, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhou, R, Zhang, X, Tang, X, Dong, H. | | Deposit date: | 2022-11-14 | | Release date: | 2023-04-26 | | Last modified: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of BAM-mediated outer membrane beta-barrel protein assembly.
Nature, 617, 2023
|
|
8BE8
 | | Crystal structure of SOS1-HRas-peptidomimetic4 | | Descriptor: | FORMIC ACID, GTPase HRas, SOS1-HRas-peptidomimetic4, ... | | Authors: | Fischer, B, Wohlkonig, A, Steyaert, J. | | Deposit date: | 2022-10-21 | | Release date: | 2023-04-26 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
8BE6
 | | Crystal structure of SOS1-HRas-peptidomimetic2 | | Descriptor: | GTPase HRas, SOS1-HRas-peptidomimetic2, Son of sevenless homolog 1 | | Authors: | Fischer, B, Wohlkonig, A, Steyaert, J. | | Deposit date: | 2022-10-21 | | Release date: | 2023-04-26 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.89880252 Å) | | Cite: | Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
8BE9
 | | Crystal structure of SOS1-HRas-peptidomimetic5 | | Descriptor: | CHLORIDE ION, FORMIC ACID, GTPase HRas, ... | | Authors: | Fischer, B, Wohlkonig, A, Steyaert, J. | | Deposit date: | 2022-10-21 | | Release date: | 2023-04-26 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
7MLC
 | | PYL10 bound to the ABA pan-antagonist 4a | | Descriptor: | 1-{2-[3,5-dicyclopropyl-4-(4-{[(quinoxaline-2-carbonyl)amino]methyl}-1H-1,2,3-triazol-1-yl)phenyl]acetamido}cyclohexane-1-carboxylic acid, Abscisic acid receptor PYL10, GLYCEROL | | Authors: | Peterson, F.C, Vaidya, A.S, Volkman, B.F, Cutler, S.R. | | Deposit date: | 2021-04-28 | | Release date: | 2021-09-29 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
8BEA
 | |
8BNZ
 | | BAM-EspP complex structure with BamA-G431C/EspP-N1293C mutations in nanodisc | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Shen, C, Chang, S, Luo, Q, Zhang, Z, Xie, T, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhou, R, Zhang, X, Tang, X, Dong, H. | | Deposit date: | 2022-11-14 | | Release date: | 2023-04-26 | | Last modified: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis of BAM-mediated outer membrane beta-barrel protein assembly.
Nature, 617, 2023
|
|
4UTO
 | | Crystal structure of pneumococcal surface antigen PsaA D280N in the Cd-bound, open state | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN | | Authors: | Luo, Z, Counago, R.M, Maher, M, Kobe, B. | | Deposit date: | 2014-07-22 | | Release date: | 2015-03-11 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae.
Nat Commun, 6, 2015
|
|
7MLD
 | | PYL10 bound to the ABA pan-antagonist antabactin | | Descriptor: | Abscisic acid receptor PYL10, CITRIC ACID, antabactin | | Authors: | Peterson, F.C, Vaidya, A.S, Volkman, B.F, Cutler, S.R. | | Deposit date: | 2021-04-28 | | Release date: | 2021-09-29 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
2YFU
 | | CBM62 FROM CLOSTRIDIUM THERMOCELLUM XYL5A | | Descriptor: | CALCIUM ION, CARBOHYDRATE BINDING FAMILY 6, GLYCEROL | | Authors: | Montanier, C.Y, Correia, M.A.S, Flint, J.E, Zhu, Y, Basle, A, Mckee, L.S, Prates, J.A.M, Polizzi, S.J, Coutinho, P.M, Henrissat, B, Fontes, C.M.G.A, Gilbert, H.J. | | Deposit date: | 2011-04-08 | | Release date: | 2011-05-18 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | A Novel, Noncatalytic Carbohydrate-Binding Module Displays Specificity for Galactose-Containing Polysaccharides Through Calcium-Mediated Oligomerization.
J.Biol.Chem., 286, 2011
|
|
7MUQ
 | | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 1 | | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | | Deposit date: | 2021-05-14 | | Release date: | 2021-10-06 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS.
Elife, 10, 2021
|
|
7MUY
 | | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 5 | | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | | Deposit date: | 2021-05-14 | | Release date: | 2021-10-06 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS.
Elife, 10, 2021
|
|
7MUV
 | | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 3 | | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | | Deposit date: | 2021-05-14 | | Release date: | 2021-10-06 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS.
Elife, 10, 2021
|
|
8B6U
 | | Mpf2Ba1 monomer | | Descriptor: | MAGNESIUM ION, Mpf2Ba1 | | Authors: | Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez-Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R. | | Deposit date: | 2022-09-27 | | Release date: | 2023-05-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.134 Å) | | Cite: | Structural journey of an insecticidal protein against western corn rootworm.
Nat Commun, 14, 2023
|
|
7MUW
 | | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 4 | | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | | Deposit date: | 2021-05-14 | | Release date: | 2021-10-06 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS.
Elife, 10, 2021
|
|
8B6W
 | | Mpf2Ba1 pore | | Descriptor: | MAGNESIUM ION, Mpf2Ba1 | | Authors: | Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R. | | Deposit date: | 2022-09-27 | | Release date: | 2023-05-31 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural journey of an insecticidal protein against western corn rootworm.
Nat Commun, 14, 2023
|
|
7MUD
 | | Legionella pneumophila Dot/Icm T4SS OMC | | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | | Deposit date: | 2021-05-14 | | Release date: | 2021-10-06 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS.
Elife, 10, 2021
|
|
7MUS
 | | Reconstruction of the Legionella pneumophila Dot/Icm T4SS 3DVA Map 2 | | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | | Deposit date: | 2021-05-14 | | Release date: | 2021-10-06 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS.
Elife, 10, 2021
|
|
7MUC
 | | Legionella pneumophila Dot/Icm T4SS C1 Reconstruction | | Descriptor: | DUF2807 domain-containing protein, DotC, DotD, ... | | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | | Deposit date: | 2021-05-14 | | Release date: | 2021-10-06 | | Last modified: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS.
Elife, 10, 2021
|
|
