1BGX
 
 | | TAQ POLYMERASE IN COMPLEX WITH TP7, AN INHIBITORY FAB | | Descriptor: | TAQ DNA POLYMERASE, TP7 MAB | | Authors: | Murali, R, Sharkey, D.J, Daiss, J.L, Krishna Murthy, H.M. | | Deposit date: | 1998-06-02 | | Release date: | 1998-10-14 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme.
Proc.Natl.Acad.Sci.USA, 95, 1998
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2M2T
 | | ASFV Pol X structure | | Descriptor: | Repair DNA polymerase X | | Authors: | Wu, W, Su, M, Tsai, M. | | Deposit date: | 2013-01-03 | | Release date: | 2014-04-02 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation.
J.Am.Chem.Soc., 136, 2014
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4MG2
 | | ALKBH2 F102A cross-linked to undamaged dsDNA | | Descriptor: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA-1, DNA-2, ... | | Authors: | Chen, B, Gan, J, Yang, C.G. | | Deposit date: | 2013-08-28 | | Release date: | 2014-02-26 | | Last modified: | 2014-06-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The complex structures of ALKBH2 mutants cross-linked to
dsDNA reveal the conformational swing of β-hairpin
Sci China Chem, 57, 2014
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1DSI
 | | Solution structure of a duocarmycin sa-indole-alkylated dna dupleX | | Descriptor: | 4-HYDROXY-6-(1H-INDOLE-2-CARBONYL)-8-METHYL-3,6,7,8-TETRAHYDRO-3,6-DIAZA-AS-INDACENE-2-CARBOXYLIC ACID METHYL ESTER, DNA (5'-D(*GP*AP*CP*TP*AP*AP*TP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*AP*TP*TP*AP*GP*TP*C)-3') | | Authors: | Schnell, J.R, Ketchem, R.R, Boger, D.L, Chazin, W.J. | | Deposit date: | 1998-07-29 | | Release date: | 1998-08-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Binding-Induced Activation of DNA Alkylation by Duocarmycin SA: Insights from the Structure of an Indole Derivative-DNA Adduct
J.Am.Chem.Soc., 121, 1999
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8PM7
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3AJJ
 | | Crystal Structure of d(CGCGGATf5UCGCG): 5-Formyluridine/Guanosine Base-pair in B-DNA | | Descriptor: | 5'-D(*CP*GP*CP*GP*GP*AP*TP*(UFR)P*CP*GP*CP*G)-3' | | Authors: | Tsunoda, M, Sakaue, T, Ueno, Y, Matsuda, A, Takenaka, A. | | Deposit date: | 2010-06-07 | | Release date: | 2011-04-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.02 Å) | | Cite: | Insights into the structures of DNA damaged by hydroxyl radical: crystal structures of DNA duplexes containing 5-formyluracil
J Nucleic Acids, 2010, 2010
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1T3W
 | | Crystal Structure of the E.coli DnaG C-terminal domain (residues 434 to 581) | | Descriptor: | ACETIC ACID, DNA primase | | Authors: | Oakley, A.J, Loscha, K.V, Schaeffer, P.M, Liepinsh, E, Wilce, M.C.J, Otting, G, Dixon, N.E. | | Deposit date: | 2004-04-28 | | Release date: | 2004-11-02 | | Last modified: | 2016-09-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal and solution structures of the helicase-binding domain of Escherichia coli primase
J.Biol.Chem., 280, 2005
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3CRX
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2ODI
 | | Restriction Endonuclease BCNI-Cognate DNA Substrate Complex | | Descriptor: | 5'-D(*AP*AP*CP*CP*CP*GP*GP*AP*GP*AP*C)-3', 5'-D(*CP*TP*CP*CP*GP*GP*GP*TP*TP*GP*T)-3', CALCIUM ION, ... | | Authors: | Sokolowska, M, Kaus-Drobek, M, Czapinska, H, Tamulaitis, G, Szczepanowski, R.H, Urbanke, C, Siksnys, V, Bochtler, M. | | Deposit date: | 2006-12-22 | | Release date: | 2007-03-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.
J.Mol.Biol., 369, 2007
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4L6P
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8URQ
 | | Spo11 core complex with gapped DNA | | Descriptor: | Antiviral protein SKI8, MAGNESIUM ION, Meiosis-specific protein SPO11, ... | | Authors: | Yu, Y, Patel, D.J. | | Deposit date: | 2023-10-26 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structure of the yeast Spo11 core complex bound to DNA
To Be Published
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4OCD
 | | In and Out the minor groove: Interaction of an AT rich-DNA with the CD27 drug | | Descriptor: | N1-(4,5-dihydro-1H-imidazol-2-yl)-N4-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzene-1,4-diamine, d(AAAATTTT) | | Authors: | Acosta-Reyes, F.J, Dardonville, C, de Koning, H.P, Natto, M, Subirana, J.A, Campos, J.L. | | Deposit date: | 2014-01-08 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27
Acta Crystallogr.,Sect.D, D70, 2014
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4L5E
 | | Crystal structure of A. aeolicus NtrC1 DNA binding domain | | Descriptor: | SULFATE ION, Transcriptional regulator (NtrC family) | | Authors: | Young, A, Maris, A.E, Vidangos, N.K, Hong, E, Pelton, J.G, Batchelor, J.D, Wemmer, D.E. | | Deposit date: | 2013-06-10 | | Release date: | 2013-08-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Structure, function, and tethering of DNA-binding domains in sigma (54) transcriptional activators.
Biopolymers, 99, 2013
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4R2H
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8URU
 | | Spo11 core complex with hairpin DNA | | Descriptor: | Antiviral protein SKI8, Hairpin DNA, MAGNESIUM ION, ... | | Authors: | Yu, Y, Patel, D.J. | | Deposit date: | 2023-10-26 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structure of the yeast Spo11 core complex bound to DNA
To Be Published
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3SSE
 | | DNA binding domain of restriction endonuclease bound to DNA | | Descriptor: | 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*A*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*T*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3') | | Authors: | Sukackaite, R, Grazulis, S, Siksnys, V. | | Deposit date: | 2011-07-08 | | Release date: | 2012-05-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine.
Nucleic Acids Res., 40, 2012
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3UPQ
 | | Crystal structure of the pre-catalytic ternary complex of polymerase lambda with an rATP analog opposite a templating T. | | Descriptor: | 5'-D(*CP*AP*GP*TP*AP*C)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... | | Authors: | Gosavi, R.A, Moon, A.F, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | | Deposit date: | 2011-11-18 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda
Nucleic Acids Res., 40, 2012
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1RH6
 | | Bacteriophage Lambda Excisionase (Xis)-DNA Complex | | Descriptor: | 5'-D(*CP*TP*AP*TP*GP*TP*AP*GP*TP*CP*TP*GP*TP*TP*G)-3', 5'-D(P*CP*AP*AP*CP*AP*GP*AP*CP*TP*AP*CP*AP*TP*AP*G)-3', Excisionase | | Authors: | Sam, M.D, Cascio, D, Johnson, R.C, Clubb, R.T. | | Deposit date: | 2003-11-13 | | Release date: | 2004-06-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of the excisionase-DNA complex from bacteriophage lambda.
J.Mol.Biol., 338, 2004
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7DQ0
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3SSC
 | | DNA binding domain of restriction endonuclease bound to DNA | | Descriptor: | 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*AP*GP*CP*TP*AP*(5CM)P*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*AP*(5CM)P*CP*GP*GP*TP*AP*GP*C)-3') | | Authors: | Sukackaite, R, Grazulis, S, Siksnys, V. | | Deposit date: | 2011-07-08 | | Release date: | 2012-05-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine.
Nucleic Acids Res., 40, 2012
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3UQ0
 | | Crystal structure of the post-catalytic product complex of polymerase lambda with an rAMP at the primer terminus. | | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*GP*TP*AP*CP)-R(P*A)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', ... | | Authors: | Gosavi, R.A, Moon, A.F, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | | Deposit date: | 2011-11-18 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda
Nucleic Acids Res., 40, 2012
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3GP1
 | | MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC3-V222P complex | | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*GP*CP**C)-3', 5'-D(P*TP*GP*CP*GP*TP*CP*CP*(8OG)P*GP*AP*TP*CP*TP*AP*CP*C)-3', DNA glycosylase, ... | | Authors: | Spong, M.C, Qi, Y, Verdine, G.L. | | Deposit date: | 2009-03-20 | | Release date: | 2009-11-10 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme
Nature, 462, 2009
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3UQ2
 | | Crystal structure of the post-catalytic product complex of polymerase lambda with an rCMP inserted opposite a templating G and dAMP inserted opposite a templating T at the primer terminus. | | Descriptor: | 5'-D(*CP*AP*GP*TP*AP)-R(P*CP*A)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... | | Authors: | Gosavi, R.A, Moon, A.F, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | | Deposit date: | 2011-11-18 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda
Nucleic Acids Res., 40, 2012
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3C46
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3G0Q
 | | Crystal Structure of MutY bound to its inhibitor DNA | | Descriptor: | 5'-D(*AP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*CP*AP*GP*TP*CP*TP*T)-3', A/G-specific adenine glycosylase, ... | | Authors: | Lee, S, Verdine, G.L. | | Deposit date: | 2009-01-28 | | Release date: | 2009-11-17 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase.
Proc.Natl.Acad.Sci.Usa, 106, 2009
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