3GP1

MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC3-V222P complex

Summary for 3GP1

• Entry DOI: 10.2210/pdb3gp1/pdb
• Descriptor: DNA glycosylase, 5'-D(*AP*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*GP*CP**C)-3', 5'-D(P*TP*GP*CP*GP*TP*CP*CP*(8OG)P*GP*AP*TP*CP*TP*AP*CP*C)-3', ... (5 entities in total)
• Functional Keywords: dna glycosylase, dna repair, damage search, base extrusion, disulfide crosslinking, dna damage, dna-binding, glycosidase, hydrolase, lyase, metal-binding, multifunctional enzyme, zinc-finger, hydrolase-dna complex, hydrolase/dna
• Biological source: Geobacillus stearothermophilus; More
• Total number of polymer chains: 3
• Total formula weight: 40171.90

Authors

Spong, M.C.,Qi, Y.,Verdine, G.L. (deposition date: 2009-03-20, release date: 2009-11-10, Last modification date: 2023-09-06)

• Primary citation: Qi, Y.,Spong, M.C.,Nam, K.,Banerjee, A.,Jiralerspong, S.,Karplus, M.,Verdine, G.L.; Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme; Nature, 462:762-766, 2009; PubMed: 20010681; DOI: 10.1038/nature08561

Experimental method

X-RAY DIFFRACTION (2.05 Å)