3GP1
MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC3-V222P complex
Summary for 3GP1
Entry DOI | 10.2210/pdb3gp1/pdb |
Descriptor | DNA glycosylase, 5'-D(*AP*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*GP*CP**C)-3', 5'-D(P*TP*GP*CP*GP*TP*CP*CP*(8OG)P*GP*AP*TP*CP*TP*AP*CP*C)-3', ... (5 entities in total) |
Functional Keywords | dna glycosylase, dna repair, damage search, base extrusion, disulfide crosslinking, dna damage, dna-binding, glycosidase, hydrolase, lyase, metal-binding, multifunctional enzyme, zinc-finger, hydrolase-dna complex, hydrolase/dna |
Biological source | Geobacillus stearothermophilus More |
Total number of polymer chains | 3 |
Total formula weight | 40171.90 |
Authors | Spong, M.C.,Qi, Y.,Verdine, G.L. (deposition date: 2009-03-20, release date: 2009-11-10, Last modification date: 2023-09-06) |
Primary citation | Qi, Y.,Spong, M.C.,Nam, K.,Banerjee, A.,Jiralerspong, S.,Karplus, M.,Verdine, G.L. Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme Nature, 462:762-766, 2009 Cited by PubMed: 20010681DOI: 10.1038/nature08561 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report