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1L1F
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BU of 1l1f by Molmil
Structure of human glutamate dehydrogenase-apo form
Descriptor: Glutamate Dehydrogenase 1
Authors:Smith, T.J, Schmidt, T, Fang, J, Wu, J, Siuzdak, G, Stanley, C.A.
Deposit date:2002-02-15
Release date:2002-03-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of apo human glutamate dehydrogenase details subunit communication and allostery.
J.Mol.Biol., 318, 2002
6JND
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BU of 6jnd by Molmil
Cryo-EM structure of glutamate dehydrogenase from Thermococcus profundus
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutamate dehydrogenase
Authors:Oide, M, Kato, T, Oroguchi, T, Nakasako, M.
Deposit date:2019-03-14
Release date:2020-02-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Energy landscape of domain motion in glutamate dehydrogenase deduced from cryo-electron microscopy.
Febs J., 287, 2020
6G2U
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BU of 6g2u by Molmil
Crystal structure of the human glutamate dehydrogenase 2 (hGDH2)
Descriptor: CHLORIDE ION, Glutamate dehydrogenase 2, mitochondrial, ...
Authors:Fadouloglou, V.F, Dimovasili, C, Providaki, M, Kotsifaki, D, Sarrou, I, Plaitakis, A, Zaganas, I, Kokkinidis, M.
Deposit date:2018-03-23
Release date:2019-04-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.934287 Å)
Cite:Crystal structure of glutamate dehydrogenase 2, a positively selected novel human enzyme involved in brain biology and cancer pathophysiology.
J.Neurochem., 2021
8SK8
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BU of 8sk8 by Molmil
human liver mitochondrial Glutamate dehydrogenase 1
Descriptor: Glutamate dehydrogenase 1, mitochondrial
Authors:Zhang, Z, Tringides, M.
Deposit date:2023-04-18
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.31 Å)
Cite:High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology.
Mol.Cell Proteomics, 22, 2023
1LEH
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BU of 1leh by Molmil
LEUCINE DEHYDROGENASE FROM BACILLUS SPHAERICUS
Descriptor: LEUCINE DEHYDROGENASE
Authors:Baker, P.J, Turnbull, A.P, Sedelnikova, S.E, Stillman, T.J, Rice, D.W.
Deposit date:1995-06-09
Release date:1996-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A role for quaternary structure in the substrate specificity of leucine dehydrogenase.
Structure, 3, 1995
3AOE
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BU of 3aoe by Molmil
Crystal structure of hetero-hexameric glutamate dehydrogenase from Thermus thermophilus (Leu bound form)
Descriptor: Glutamate dehydrogenase, LEUCINE
Authors:Tomita, T, Kuzuyama, T, Nishiyama, M.
Deposit date:2010-09-27
Release date:2011-09-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An unique allosteric regulation revealed by hetero-hexameric glutamate dehydrogenase from Thermus thermophilus
To be Published
3AOG
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BU of 3aog by Molmil
Crystal structure of glutamate dehydrogenase (GdhB) from Thermus thermophilus (Glu bound form)
Descriptor: AMMONIUM ION, GLUTAMIC ACID, Glutamate dehydrogenase, ...
Authors:Tomita, T, Kuzuyama, T, Nishiyama, M.
Deposit date:2010-09-28
Release date:2011-09-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An unique allosteric regulation revealed by crystal structure of hetero-hexameric glutamate dehydrogenase from Thermus thermophilus
To be Published
5XVV
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BU of 5xvv by Molmil
Crystal Structure of Forward Inhibited Aspergillus niger Glutamate Dehydrogenase With Both Apo- and Alpha Ketoglutarate Bound Subunits
Descriptor: 2-OXOGLUTARIC ACID, BETA-MERCAPTOETHANOL, GLYCEROL, ...
Authors:Prakash, P, Punekar, N.S, Bhaumik, P.
Deposit date:2017-06-28
Release date:2018-03-21
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
5XW0
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BU of 5xw0 by Molmil
Crystal Structure of Aspergillus niger Glutamate Dehydrogenase Complexed With Isophthalate and NADPH
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Glutamate dehydrogenase, ...
Authors:Prakash, P, Punekar, N.S, Bhaumik, P.
Deposit date:2017-06-28
Release date:2018-03-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
5XVI
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BU of 5xvi by Molmil
Crystal Structure of Aspergillus niger Apo- Glutamate Dehydrogenase
Descriptor: GLYCEROL, Glutamate dehydrogenase
Authors:Prakash, P, Punekar, N.S, Bhaumik, P.
Deposit date:2017-06-28
Release date:2018-03-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
5XWC
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Crystal Structure of Aspergillus niger Glutamate Dehydrogenase Complexed With Alpha-iminoglutarate, 2-amino-2-hydroxyglutarate and NADP
Descriptor: (2S)-2-azanyl-2-oxidanyl-pentanedioic acid, (2Z)-2-iminopentanedioic acid, DI(HYDROXYETHYL)ETHER, ...
Authors:Prakash, P, Punekar, N.S, Bhaumik, P.
Deposit date:2017-06-29
Release date:2018-03-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
7F79
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BU of 7f79 by Molmil
Crystal structure of glutamate dehydrogenase 3 from Candida albicans in complex with alpha-ketoglutarate and NADPH
Descriptor: 2-OXOGLUTARIC ACID, GLYCEROL, Glutamate dehydrogenase, ...
Authors:Li, N, Wang, W, Zeng, X, Liu, M, Li, M, Li, C, Wang, M.
Deposit date:2021-06-28
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of glutamate dehydrogenase 3 from Candida albicans.
Biochem.Biophys.Res.Commun., 570, 2021
7F77
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BU of 7f77 by Molmil
Crystal structure of glutamate dehydrogenase 3 from Candida albicans
Descriptor: Glutamate dehydrogenase
Authors:Li, N, Wang, W, Zeng, X, Liu, M, Li, M, Li, C, Wang, M.
Deposit date:2021-06-28
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.086 Å)
Cite:Crystal structure of glutamate dehydrogenase 3 from Candida albicans.
Biochem.Biophys.Res.Commun., 570, 2021
7ECT
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BU of 7ect by Molmil
Crystal Structure of Aspergillus terreus Glutamate Dehydrogenase (AtGDH) Complexed With Tartrate and NADPH
Descriptor: GLYCEROL, Glutamate dehydrogenase, L(+)-TARTARIC ACID, ...
Authors:Godsora, B.K.J, Prakash, P, Punekar, N.S, Bhaumik, P.
Deposit date:2021-03-13
Release date:2021-12-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular insights into the inhibition of glutamate dehydrogenase by the dicarboxylic acid metabolites.
Proteins, 90, 2022
7ECR
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BU of 7ecr by Molmil
Crystal Structure of Aspergillus terreus Glutamate Dehydrogenase (AtGDH) Complexed With Succinate and ADP-ribose
Descriptor: GLYCEROL, Glutamate dehydrogenase, SUCCINIC ACID, ...
Authors:Godsora, B.K.J, Prakash, P, Punekar, N.S, Bhaumik, P.
Deposit date:2021-03-13
Release date:2021-12-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Molecular insights into the inhibition of glutamate dehydrogenase by the dicarboxylic acid metabolites.
Proteins, 90, 2022
7ECS
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BU of 7ecs by Molmil
Crystal Structure of Aspergillus terreus Glutamate Dehydrogenase (AtGDH) Complexed With Malonate and NADPH
Descriptor: GLYCEROL, Glutamate dehydrogenase, MALONATE ION, ...
Authors:Godsora, B.K.J, Prakash, P, Punekar, N.S, Bhaumik, P.
Deposit date:2021-03-13
Release date:2021-12-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Molecular insights into the inhibition of glutamate dehydrogenase by the dicarboxylic acid metabolites.
Proteins, 90, 2022
5XVX
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BU of 5xvx by Molmil
Crystal Structure of Aspergillus niger Glutamate Dehydrogenase Complexed With Alpha-ketoglutarate and NADPH
Descriptor: 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Prakash, P, Punekar, N.S, Bhaumik, P.
Deposit date:2017-06-28
Release date:2018-03-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase.
J. Biol. Chem., 293, 2018
8ZNB
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BU of 8znb by Molmil
Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH in the steady stage of reaction
Descriptor: Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wakabayashi, T, Nakasako, M.
Deposit date:2024-05-26
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action
To Be Published
8ZNC
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BU of 8znc by Molmil
Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH, AKG in the steady stage of reaction
Descriptor: 2-OXOGLUTARIC ACID, AMMONIUM ION, Glutamate dehydrogenase, ...
Authors:Wakabayashi, T, Nakasako, M.
Deposit date:2024-05-26
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action
To Be Published
8ZMU
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BU of 8zmu by Molmil
GLUTAMATE DEHYDROGENASE (W89F-MUTANT) FROM THERMOCOCCUS PROFUNDUS IN THE UNLIGANDED STATE
Descriptor: ACETIC ACID, GLYCEROL, Glutamate dehydrogenase, ...
Authors:Wakabayashi, T, Matsui, Y, Masayoshi, M.
Deposit date:2024-05-23
Release date:2024-06-05
Method:X-RAY DIFFRACTION (2.028 Å)
Cite:Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by cryoEM-sampling metastable conformation in action
To Be Published
8ZND
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BU of 8znd by Molmil
Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH and a substrate in the steady stage of reaction
Descriptor: Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wakabayashi, T, Nakasako, M.
Deposit date:2024-05-26
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action
To Be Published
8ZNG
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BU of 8zng by Molmil
Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus in complex with NADPH and AKG in the steady stage of reaction
Descriptor: 2-OXOGLUTARIC ACID, Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wakabayashi, T, Nakasako, M.
Deposit date:2024-05-26
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action
To Be Published
8ZNE
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BU of 8zne by Molmil
Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus in complex with NADP and GLU in the steady stage of reaction
Descriptor: GLUTAMIC ACID, Glutamate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wakabayashi, T, Nakasako, M.
Deposit date:2024-05-26
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by cryoEM-sampling metastable conformation in action
To Be Published
8HJ9
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BU of 8hj9 by Molmil
cryoEM structure of glutamate dehydrogenase from Thermococcus profundus in complex with NADP
Descriptor: Glutamate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wakabayashi, T, Oide, M, Kato, T, Nakasako, M.
Deposit date:2022-11-22
Release date:2023-02-08
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Coenzyme-binding pathway on glutamate dehydrogenase suggested from multiple-binding sites visualized by cryo-electron microscopy.
Febs J., 290, 2023
8HJ3
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BU of 8hj3 by Molmil
cryoEM structure of glutamate dehydrogenase from Thermococcus profundus in complex with NADP
Descriptor: Glutamate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wakabayashi, T, Oide, M, Kato, T, Nakasako, M.
Deposit date:2022-11-22
Release date:2023-02-08
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Coenzyme-binding pathway on glutamate dehydrogenase suggested from multiple-binding sites visualized by cryo-electron microscopy.
Febs J., 290, 2023

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数据于2024-07-10公开中

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