5XVV

Crystal Structure of Forward Inhibited Aspergillus niger Glutamate Dehydrogenase With Both Apo- and Alpha Ketoglutarate Bound Subunits

Summary for 5XVV

Entry DOI	10.2210/pdb5xvv/pdb
Descriptor	Glutamate dehydrogenase, GLYCEROL, 2-OXOGLUTARIC ACID, ... (5 entities in total)
Functional Keywords	aspergillus, glutamate, dehydrogenase, 2-oxoglutarate, allostery, forward inhibition, 2-mercaptoethanol, oxidoreductase
Biological source	Aspergillus niger
Total number of polymer chains	6
Total formula weight	299588.21
Authors	Prakash, P.,Punekar, N.S.,Bhaumik, P. (deposition date: 2017-06-28, release date: 2018-03-21, Last modification date: 2018-05-09)
Primary citation	Prakash, P.,Punekar, N.S.,Bhaumik, P. Structural basis for the catalytic mechanism and alpha-ketoglutarate cooperativity of glutamate dehydrogenase. J. Biol. Chem., 293:6241-6258, 2018 Cited by PubMed: 29540480 DOI: 10.1074/jbc.RA117.000149 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation