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7UMM	H1 Solomon Islands 2006 hemagglutinin in complex with Ab109 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Windsor, I.W, Caradonna, T.M, Schmidt, A.G. Deposit date: 2022-04-07 Release date: 2022-11-23 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: An epitope-enriched immunogen expands responses to a conserved viral site. Cell Rep, 41, 2022
7UMN	H1 Solomon Islands 2006 hemagglutinin in complex with Ab36 Descriptor: Ab36 Fab heavy chain, Ab36 Fab light chain, Hemagglutinin Authors: Windsor, I.W, Caradonna, T.M, Schmidt, A.G. Deposit date: 2022-04-07 Release date: 2023-04-19 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: H1 Solomon Islands 2006 hemagglutinin in complex with Ab36 To Be Published
7U8J	Crystal structure of chimeric hemagglutinin cH4/3 in complex with broad protective antibody 31.a.83 Descriptor: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ... Authors: Zhu, X, Wilson, I.A. Deposit date: 2022-03-08 Release date: 2022-06-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4.9 Å) Cite: Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proc.Natl.Acad.Sci.USA, 119, 2022
7U8L	Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibody 31.a.83 Descriptor: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ... Authors: Zhu, X, Wilson, I.A. Deposit date: 2022-03-08 Release date: 2022-06-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4.56 Å) Cite: Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proc.Natl.Acad.Sci.USA, 119, 2022
7U8M	Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibodies 31.a.83 and FluA-20 Descriptor: Antibody 31.a.83 Fab light chain, antibody 31.a.83 Fab heavy chain, antibody FluA-20 Fab heavy chain, ... Authors: Zhu, X, Wilson, I.A. Deposit date: 2022-03-08 Release date: 2022-06-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (5.39 Å) Cite: Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface. Proc.Natl.Acad.Sci.USA, 119, 2022
7X6L	Cryo-EM structure of H3 hemagglutinin from A/HongKong/01/1968 in complex with a neutralizing antibody 28-12 Descriptor: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of the antibody 12 fab Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-07 Release date: 2022-03-23 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus. Nat Commun, 13, 2022
7X6O	Cryo-EM structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 28-12 Descriptor: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of antibody 12 fab Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-07 Release date: 2022-03-23 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus. Nat Commun, 13, 2022
7TZ5	Cryo-EM structure of antibody TJ5-5 bound to H3 COBRA TJ5 hemagglutinin Descriptor: Hemagglutinin, TJ5-5 heavy chain, TJ5-5 light chain Authors: Abbadi, N.S, Mousa, J.J. Deposit date: 2022-02-15 Release date: 2022-07-06 Last modified: 2022-09-21 Method: ELECTRON MICROSCOPY (3.41 Å) Cite: Differential Recognition of Computationally Optimized H3 Hemagglutinin Influenza Vaccine Candidates by Human Antibodies. J.Virol., 96, 2022
7WVG	Crystal structure of H18 complexed with SIA28 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... Authors: Chen, Y, Qi, J, Gao, G.F. Deposit date: 2022-02-10 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
7WVD	Crystal structure of H14 complexed with SIA28 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... Authors: Chen, Y, Qi, J, Gao, G.F. Deposit date: 2022-02-10 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.39 Å) Cite: Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
7TRH	Human antibody K03.28 in complex with the influenza hemagglutinin head domain of A/California/07/2009(H1N1)(X-181) Descriptor: Hemagglutinin, K03.28 Fab heavy chain, K03.28 Fab lambda light chain Authors: McCarthy, K.R. Deposit date: 2022-01-28 Release date: 2023-08-02 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (3 Å) Cite: A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses. Plos Biol., 21, 2023
7TRI	Human antibody S8V1-172 in complex with the influenza hemagglutinin head domain of A/Sydney/05/1997(H3N2) Descriptor: Hemagglutinin, S8V1-172 Fab heavy chain, S8V1-172 Fab kappa light chain, ... Authors: McCarthy, K.R. Deposit date: 2022-01-28 Release date: 2023-08-02 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (3.6 Å) Cite: A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses. Plos Biol., 21, 2023
7WL5	Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wei, X, Yang, X, Chen, Q, Meng, G. Deposit date: 2022-01-12 Release date: 2023-01-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1) To Be Published
7T3D	CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 222-1C06 mAb heavy chain, ... Authors: Han, J, Ward, A.B. Deposit date: 2021-12-07 Release date: 2022-01-12 Last modified: 2022-03-30 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Broadly neutralizing antibodies target a haemagglutinin anchor epitope. Nature, 602, 2022
7T1V	Crystal structure of an equine H7 hemagglutinin from A/equine/NY/49/73 (H7N7) in complex with 3'-GcLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Zhu, X, Wilson, I.A. Deposit date: 2021-12-02 Release date: 2022-01-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.05 Å) Cite: N -Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses. J.Virol., 96, 2022
7QA4	Crystal structure of stabilized H3N2 A/Hong Kong/1/1968 Hemagglutinin at 2.2 Angstrom Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Milder, F.J, Langedijk, J.P.M. Deposit date: 2021-11-16 Release date: 2022-02-02 Last modified: 2022-03-30 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions. Proc.Natl.Acad.Sci.USA, 119, 2022
7SCN	Structure of H1 NC99 influenza hemagglutinin bound to Fab 310-63E6 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-63E6 Fab, Heavy Chain, ... Authors: Ward, A, Torrents de la Pena, A. Deposit date: 2021-09-28 Release date: 2022-08-24 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.02 Å) Cite: Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus. Immunity, 55, 2022
7SCO	Structure of H1 influenza hemagglutinin bound to Fab 310-39G10 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 310-39G10 Fab, ... Authors: Torrents de la Pena, A, Ward, A.B. Deposit date: 2021-09-28 Release date: 2022-08-24 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.37 Å) Cite: Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus. Immunity, 55, 2022
7VDF	2.56 A structure of influenza hemagglutinin (HA) trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose Authors: Fan, H.C, Zhang, Y, Sun, F. Deposit date: 2021-09-06 Release date: 2021-12-29 Method: ELECTRON MICROSCOPY (2.56 Å) Cite: A cryo-electron microscopy support film formed by 2D crystals of hydrophobin HFBI. Nat Commun, 12, 2021
7RDH	Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ... Authors: Kadam, R.U, Wilson, I.A. Deposit date: 2021-07-09 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
7RCR	Crystal Structure of the refolded Hemagglutinin head domain of Influenza A virus A/Ohio/09/2015 Descriptor: 1,2-ETHANEDIOL, Hemagglutinin Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-07-08 Release date: 2021-08-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of the refolded Hemagglutinin head domain of Influenzavirus A Influenza A virus A/Ohio/09/2015 to be published
7FAH	Immune complex of head region of CA09 HA and neutralizing antibody 12H5 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Li, T.T, Xue, W.H, Gu, Y, Li, S.W. Deposit date: 2021-07-06 Release date: 2022-07-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.151 Å) Cite: Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
7MFG	Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-030-1D06 Heavy, 310-030-1D06 Light, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2021-04-09 Release date: 2021-11-03 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (3.87 Å) Cite: A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28, 2022
7MEM	CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 045-09 2B05, ... Authors: Han, J, Ward, A. Deposit date: 2021-04-06 Release date: 2021-07-28 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Sci Transl Med, 13, 2021
7L0L	Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 316-310-1B11 Heavy Chain, 316-310-1B11 Light Chain, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2020-12-11 Release date: 2021-11-03 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28, 2022

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