PDB: 934 resultsInfo pagesStatus searchChemie searchBIRD

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5UZM	Crystal structure of Glorund qRRM2 domain Descriptor: AT27789p Authors: Teramoto, T, Hall, T.M.T. Deposit date: 2017-02-27 Release date: 2017-03-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.552 Å) Cite: The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition. Cell Rep, 19, 2017
1M5K	Crystal structure of a hairpin ribozyme in the catalytically-active conformation Descriptor: CALCIUM ION, CHLORIDE ION, PROTEIN (U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A), ... Authors: Rupert, P.B, Ferre-D'Amare, A.R. Deposit date: 2002-07-09 Release date: 2002-08-02 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Transition state stabilization by a catalytic RNA Science, 298, 2002
1M5V	Transition State Stabilization by a Catalytic RNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, RNA HAIRPIN RIBOZYME, ... Authors: Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R. Deposit date: 2002-07-09 Release date: 2002-10-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Transition state stabilization by a catalytic RNA Science, 298, 2002
5IM0	Crystal structure of the RNA recognition motif of mRNA decay regulator AUF1 Descriptor: Heterogeneous nuclear ribonucleoprotein D0 Authors: Choi, Y.J, Chang, J.H. Deposit date: 2016-03-05 Release date: 2016-08-03 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of the N-Terminal RNA Recognition Motif of mRNA Decay Regulator AUF1. Biomed Res Int, 2016, 2016
6NSX	Yeast Hsh155 Ligand bound to Human Tat-SF1 Motif Descriptor: CHLORIDE ION, HIV Tat-specific factor 1, Hsh155 Authors: Jenkins, J.L, Leach, J.R, Kielkopf, C.L. Deposit date: 2019-01-25 Release date: 2019-06-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction. Rna, 25, 2019
6NTY	2.1 A resolution structure of the Musashi-2 (Msi2) RNA recognition motif 1 (RRM1) domain Descriptor: PHOSPHATE ION, RNA-binding protein Musashi homolog 2 Authors: Lovell, S, Kashipathy, M.M, Battaile, K.P, Lan, L, Xiaoqing, W, Cooper, A, Gao, F.P, Xu, L. Deposit date: 2019-01-30 Release date: 2019-10-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1. Proteins, 88, 2020
3IRW	Structure of a c-di-GMP riboswitch from V. cholerae Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ... Authors: Smith, K.D. Deposit date: 2009-08-24 Release date: 2009-11-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural basis of ligand binding by a c-di-GMP riboswitch. Nat.Struct.Mol.Biol., 16, 2009
6NWW	Crystal structure of the RRM domain of S. pombe Puf1 in the P212121 space group Descriptor: CHLORIDE ION, Pumilio domain-containing protein C56F2.08c Authors: Qiu, C, Hall, T.M.T. Deposit date: 2019-02-07 Release date: 2019-07-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity. Nucleic Acids Res., 47, 2019
5EN1	Crystal structure of hnRNPA2B1 in complex with RNA Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3') Authors: Wu, B.X, Su, S.C, Ma, J.B. Deposit date: 2015-11-09 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1 Nat Commun, 2018
6NX5	Crystal structure of the RRM domain of S. pombe Puf1 in the P21 space group Descriptor: 1,2-ETHANEDIOL, Pumilio domain-containing protein C56F2.08c Authors: Qiu, C, Hall, T.M.T. Deposit date: 2019-02-08 Release date: 2019-07-03 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.554 Å) Cite: Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity. Nucleic Acids Res., 47, 2019
5ITH	TIA-1 RRM2 recognition of target oligonucleotide Descriptor: DNA (5'-D(*AP*CP*TP*CP*C*TP*TP*TP*TP*T)-3'), Nucleolysin TIA-1 isoform p40 Authors: Waris, S, Wilce, J.A, Wilce, M.C. Deposit date: 2016-03-16 Release date: 2017-02-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.31 Å) Cite: TIA-1 RRM23 binding and recognition of target oligonucleotides. Nucleic Acids Res., 45, 2017
4Y00	Crystal Structure of Human TDP-43 RRM1 Domain with D169G Mutation in Complex with an Unmodified Single-stranded DNA Descriptor: DNA (5'-D(P*TP*TP*GP*AP*GP*CP*GP*T)-3'), TAR DNA-binding protein 43 Authors: Chiang, C.H, Kuo, P.H, Yang, W.Z, Yuan, H.S. Deposit date: 2015-02-05 Release date: 2016-02-10 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation Sci Rep, 6, 2016
3IIN	Plasticity of the kink turn structural motif Descriptor: DNA/RNA (5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*GP*AP*CP*C)-D(P*AP*GP*A)-R(P*CP*GP*GP*CP*C)-3'), DNA/RNA (5'-R(*CP*A)-D(P*T)-3'), Group I intron, ... Authors: Lipchock, S.V, Strobel, S.A, Antonioli, A.H, Cochrane, J.C. Deposit date: 2009-08-02 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (4.18 Å) Cite: Plasticity of the RNA kink turn structural motif. Rna, 16, 2010
4Y0F	Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA Descriptor: DNA (5'-D(*GP*TP*TP*GP*AP*GP*CP*GP*TP*T)-3'), TAR DNA-binding protein 43 Authors: Chiang, C.H, Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yuan, H.S. Deposit date: 2015-02-06 Release date: 2016-02-10 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.648 Å) Cite: Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation Sci Rep, 6, 2016
3K0J	Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module Descriptor: MAGNESIUM ION, RNA (87-MER), THIAMINE DIPHOSPHATE, ... Authors: Kulshina, N, Edwards, T.E, Ferre-D'Amare, A.R. Deposit date: 2009-09-24 Release date: 2009-12-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch. Rna, 16, 2010
5EV1	Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ... Authors: Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2015-11-19 Release date: 2016-02-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.037 Å) Cite: An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV2	Structure II of Intact U2AF65 Recognizing the 3' Splice Site Signal Descriptor: 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, DNA (5'-R(P*UP*U)-D(P*UP*U)-R(P*U)-D(P*UP*(BRU)P*U)-3'), ... Authors: Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2015-11-19 Release date: 2016-02-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.86 Å) Cite: An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV3	Structure III of Intact U2AF65 Recognizing the 3' Splice Site Signal Descriptor: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU)P*UP*U)-3'), Splicing factor U2AF 65 kDa subunit Authors: Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2015-11-19 Release date: 2016-02-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV4	Structure IV of Intact U2AF65 Recognizing the 3' Splice Site Signal Descriptor: DNA/RNA (5'-R(P*UP*UP*UP*(UD)P*UP*U)-D(P*(BRU)P*(UD))-R(P*C)-3'), GLYCEROL, Splicing factor U2AF 65 kDa subunit Authors: Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2015-11-19 Release date: 2016-02-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.57 Å) Cite: An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
3IWN	Co-crystal structure of a bacterial c-di-GMP riboswitch Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), C-di-GMP riboswitch, U1 small nuclear ribonucleoprotein A Authors: Kulshina, N, Baird, N.J, Ferre-D'Amare, A.R. Deposit date: 2009-09-02 Release date: 2009-11-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch. Nat.Struct.Mol.Biol., 16, 2009
3L3C	Crystal structure of the Bacillus anthracis glmS ribozyme bound to Glc6P Descriptor: 6-O-phosphono-alpha-D-glucopyranose, GLMS RIBOZYME, MAGNESIUM ION, ... Authors: Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D. Deposit date: 2009-12-16 Release date: 2009-12-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme Biochemistry, 48, 2009
4Z2X	Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from mouse at 2.15 A resolution Descriptor: Splicing factor U2AF 65 kDa subunit Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2015-03-30 Release date: 2015-04-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from mouse at 2.15 A resolution To be published
6CMN	Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7 Descriptor: TAR-Binding Protein 6.7, Trans-Activation Response RNA Element Authors: Belashov, I.A, Wedekind, J.E. Deposit date: 2018-03-05 Release date: 2018-06-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.796 Å) Cite: Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription. Nucleic Acids Res., 46, 2018
4ZKA	High Resolution Crystal Structure of Fox1 RRM Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, RNA binding protein fox-1 homolog 1, SULFATE ION, ... Authors: Blatter, M, Allain, F.H.-T. Deposit date: 2015-04-30 Release date: 2016-06-29 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: High Resolution Crystal Structure of Fox1 RRM To Be Published
4TU9	STRUCTURE OF U2AF65 VARIANT WITH BRU5G6 DNA Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DG*U)-3'), GLYCEROL, ... Authors: Jenkins, J.L, McLaughlin, K.J, Agrawal, A.A, Kielkopf, C.L. Deposit date: 2014-06-24 Release date: 2014-11-26 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.992 Å) Cite: Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Proc.Natl.Acad.Sci.USA, 111, 2014

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