6R24
 
 | | The structure of a Ty3 retrotransposon icosahedral capsid | | Descriptor: | Transposon Ty3-I Gag-Pol polyprotein | | Authors: | Dodonova, S.O, Prinz, S, Bilanchone, V, Sandmeyer, S, Briggs, J.A.G. | | Deposit date: | 2019-03-15 | | Release date: | 2019-05-08 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (7.5 Å) | | Cite: | Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4OG3
 | | Human menin with bound inhibitor MIV-3R | | Descriptor: | 4-(3-{4-[(R)-cyclopentyl(hydroxy)phenylmethyl]piperidin-1-yl}propoxy)benzonitrile, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | Authors: | He, S, Senter, T.J, Pollock, J.W, Han, C, Upadhyay, S.K, Purohit, T, Gogliotti, R.D, Lindsley, C.W, Cierpicki, T, Stauffer, S.R, Grembecka, J. | | Deposit date: | 2014-01-15 | | Release date: | 2014-03-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein-Protein Interaction.
J.Med.Chem., 57, 2014
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7Q3Z
 | | DNA/RNA binding protein | | Descriptor: | SODIUM ION, Schlafen family member 5, ZINC ION | | Authors: | Huber, E, Lammens, K. | | Deposit date: | 2021-10-29 | | Release date: | 2022-01-26 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural and biochemical characterization of human Schlafen 5.
Nucleic Acids Res., 50, 2022
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7Q5H
 | | Keap1 compound complex | | Descriptor: | (3S,5S,8R)-8-[[(2S)-1-ethanoylpyrrolidin-2-yl]carbonylamino]-N,N-dimethyl-3,7,11-tris(oxidanylidene)-10-oxa-3$l^{4}-thia-6-azabicyclo[10.4.0]hexadeca-1(16),12,14-triene-5-carboxamide, CHLORIDE ION, Kelch-like ECH-associated protein 1 | | Authors: | Johansson, P. | | Deposit date: | 2021-11-03 | | Release date: | 2022-03-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction.
J.Med.Chem., 65, 2022
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5HWV
 | | Crystal structure of PAS1 complexed with toluene | | Descriptor: | Sensor histidine kinase TodS, TOLUENE | | Authors: | Hwang, J, Koh, S. | | Deposit date: | 2016-01-29 | | Release date: | 2016-03-02 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
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3IXY
 | | The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53 | | Descriptor: | E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ... | | Authors: | Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H. | | Deposit date: | 2009-02-26 | | Release date: | 2009-10-27 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (23 Å) | | Cite: | Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
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2M5M
 | | Atomic-resolution structure of a triplet cross-beta amyloid fibril | | Descriptor: | Transthyretin | | Authors: | Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M. | | Deposit date: | 2013-02-27 | | Release date: | 2013-12-04 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (12.2 Å), SOLID-STATE NMR | | Cite: | Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
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2M5K
 | | Atomic-resolution structure of a doublet cross-beta amyloid fibril | | Descriptor: | Transthyretin | | Authors: | Fitzpatrick, A.W.P, Debelouchina, G.T, Bayro, M.J, Clare, D.K, Caporini, M.A, Bajaj, V.S, Jaroniec, C.P, Wang, L, Ladizhansky, V, Muller, S, MacPhee, C.E, Waudby, C.A, Mott, H.R, de Simone, A, Knowles, T.P.J, Saibil, H.R, Vendruscolo, M, Orlova, E.V, Griffin, R.G, Dobson, C.M. | | Deposit date: | 2013-02-27 | | Release date: | 2013-12-04 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (12.7 Å), SOLID-STATE NMR | | Cite: | Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4OG6
 | | Human menin with bound inhibitor MIV-4 | | Descriptor: | 4-(3-{4-[(R)-cyclopentyl(3-fluorophenyl)hydroxymethyl]piperidin-1-yl}propoxy)benzonitrile, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | Authors: | He, S, Senter, T.J, Pollock, J.W, Han, C, Upadhyay, S.K, Purohit, T, Gogliotti, R.D, Lindsley, C.W, Cierpicki, T, Stauffer, S.R, Grembecka, J. | | Deposit date: | 2014-01-15 | | Release date: | 2014-03-05 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein-Protein Interaction.
J.Med.Chem., 57, 2014
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6ROR
 | | REP related 18-mer DNA | | Descriptor: | REP related 18-mer DNA from C. hominis, STRONTIUM ION | | Authors: | Kolenko, P, Svoboda, J, Schneider, B. | | Deposit date: | 2019-05-13 | | Release date: | 2020-07-08 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | Structural variability of CG-rich DNA 18-mers accommodating double T-T mismatches.
Acta Crystallogr D Struct Biol, 76, 2020
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6ROS
 | | REP related 18-mer DNA | | Descriptor: | REP related 18-mer DNA from C. hominis, STRONTIUM ION | | Authors: | Kolenko, P, Svoboda, J, Schneider, B. | | Deposit date: | 2019-05-13 | | Release date: | 2020-07-08 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural variability of CG-rich DNA 18-mers accommodating double T-T mismatches.
Acta Crystallogr D Struct Biol, 76, 2020
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6KR6
 | | Crystal structure of Drosophila Piwi | | Descriptor: | MERCURY (II) ION, Protein piwi, ZINC ION, ... | | Authors: | Yamaguchi, S, Oe, A, Yamashita, K, Hirano, S, Mastumoto, N, Ishitani, R, Nishimasu, H, Nureki, O. | | Deposit date: | 2019-08-21 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of Drosophila Piwi.
Nat Commun, 11, 2020
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6RTI
 | | X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with aptamer A9g | | Descriptor: | (2S)-2-(PHOSPHONOMETHYL)PENTANEDIOIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Motlova, L, Kolenko, P, Barinka, C. | | Deposit date: | 2019-05-24 | | Release date: | 2020-06-10 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer.
Nucleic Acids Res., 48, 2020
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5AOI
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6RVO
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5EQ8
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6ZRW
 | | Crystal structure of the fungal lectin CML1 | | Descriptor: | ACETATE ION, GLYCEROL, Mucin-binding lectin 1, ... | | Authors: | Bleuler-Martinez, S, Olieric, V, Sharpe, M, Capitani, G, Aebi, M, Kuenzler, M. | | Deposit date: | 2020-07-15 | | Release date: | 2021-07-28 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity.
Glycobiology, 32, 2022
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6RWD
 | | Crystal structure of SjGST in complex with GSH and ellagic acid at 1.53 Angstrom resolution | | Descriptor: | 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione, CHLORIDE ION, GLUTATHIONE, ... | | Authors: | Olfsen, J, Pandian, R, Sayed, Y, Dirr, H.W, Achilonu, I.A. | | Deposit date: | 2019-06-04 | | Release date: | 2019-06-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Molecular basis of inhibition of Schistosoma japonicum glutathione transferase by ellagic acid: Insights into biophysical and structural studies.
Mol.Biochem.Parasitol., 240, 2020
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6RZP
 | | Multicrystal structure of Proteinase K at room temperature using a multilayer monochromator. | | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Sandy, J, Sandy, E, Sanchez-Weatherby, J, Mikolajek, H. | | Deposit date: | 2019-06-13 | | Release date: | 2019-07-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Protein-to-structure pipeline for ambient-temperature crystallography at VMXi
Iucrj, 2023
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6RO4
 | | Structure of the core TFIIH-XPA-DNA complex | | Descriptor: | DNA repair protein complementing XP-A cells, DNA1, DNA2, ... | | Authors: | Kokic, G, Chernev, A, Tegunov, D, Dienemann, C, Urlaub, H, Cramer, P. | | Deposit date: | 2019-05-10 | | Release date: | 2019-07-03 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis of TFIIH activation for nucleotide excision repair.
Nat Commun, 10, 2019
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3A5X
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7AAM
 | | Crystal structure of the F-BAR domain of PSTIPIP1 bound to the CTH domain of the phosphatase LYP | | Descriptor: | GLYCEROL, Proline-serine-threonine phosphatase-interacting protein 1, Tyrosine-protein phosphatase non-receptor type 22 | | Authors: | Manso, J.A, Alcon, P, Bayon, Y, Alonso, A, de Pereda, J.M. | | Deposit date: | 2020-09-04 | | Release date: | 2022-02-23 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders.
Cell.Mol.Life Sci., 79, 2022
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7AAN
 | | Crystal structure of the F-BAR domain of PSTIPIP1 | | Descriptor: | Proline-serine-threonine phosphatase-interacting protein 1 | | Authors: | Manso, J.A, Alcon, P, Bayon, Y, Alonso, A, de Pereda, J.M. | | Deposit date: | 2020-09-04 | | Release date: | 2022-02-23 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders.
Cell.Mol.Life Sci., 79, 2022
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3J0O
 | | Core of mammalian 80S pre-ribosome in complex with tRNAs fitted to a 9A cryo-EM map: classic PRE state 2 | | Descriptor: | 40S ribosomal RNA fragment, 60S ribosomal RNA fragment, Ribosomal protein L10a, ... | | Authors: | Budkevich, T, Giesebrecht, J, Altman, R, Munro, J, Mielke, T, Nierhaus, K, Blanchard, S, Spahn, C.M. | | Deposit date: | 2011-10-05 | | Release date: | 2011-11-16 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
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3J0Q
 | | Core of mammalian 80S pre-ribosome in complex with tRNAs fitted to a 10.6A cryo-em map: rotated PRE state 2 | | Descriptor: | 40S ribosomal RNA fragment, 60S ribosomal RNA fragment, Ribosomal protein L10, ... | | Authors: | Budkevich, T, Giesebrecht, J, Altman, R, Munro, J, Mielke, T, Nierhaus, K, Blanchard, S, Spahn, C.M. | | Deposit date: | 2011-10-11 | | Release date: | 2011-11-16 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (10.6 Å) | | Cite: | Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
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