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6XIJ
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BU of 6xij by Molmil
Escherichia coli transcription-translation complex A (TTC-A) containing an 24 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-06-20
Release date:2020-09-02
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6XZB
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BU of 6xzb by Molmil
E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification).
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L.
Deposit date:2020-02-03
Release date:2020-11-04
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
Rna, 26, 2020
6XIQ
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BU of 6xiq by Molmil
Cryo-EM Structure of K63R Ubiquitin Mutant Ribosome under Oxidative Stress
Descriptor: 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Zhou, Y, Bartesaghi, A, Silva, G.M.
Deposit date:2020-06-21
Release date:2020-08-26
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XQD
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BU of 6xqd by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UUC-mRNA, and deacylated P-site tRNA at 2.80A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S.
Deposit date:2020-07-09
Release date:2020-08-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XQE
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BU of 6xqe by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S.
Deposit date:2020-07-09
Release date:2020-08-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XU6
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BU of 6xu6 by Molmil
Drosophila melanogaster Testis 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
Authors:Hopes, T, Agapiou, M, Norris, K, McCarthy, C.G.P, OConnell, M.J, Fontana, J, Aspden, J.L.
Deposit date:2020-01-17
Release date:2021-07-28
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Nucleic Acids Res., 50, 2022
6XU8
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BU of 6xu8 by Molmil
Drosophila melanogaster Ovary 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
Authors:Hopes, T, Agapiou, M, Norris, K, McCarthy, C.G.P, OConnell, M.J, Fontana, J, Aspden, J.L.
Deposit date:2020-01-17
Release date:2021-07-28
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Nucleic Acids Res., 50, 2022
6XU7
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BU of 6xu7 by Molmil
Drosophila melanogaster Testis polysome ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
Authors:Hopes, T, Agapiou, M, Norris, K, McCarthy, C.G.P, OConnell, M.J, Fontana, J, Aspden, J.L.
Deposit date:2020-01-17
Release date:2021-07-28
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Nucleic Acids Res., 50, 2022
6Y57
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BU of 6y57 by Molmil
Structure of human ribosome in hybrid-PRE state
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
Deposit date:2020-02-25
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
6YAM
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BU of 6yam by Molmil
Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA
Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
6YEF
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BU of 6yef by Molmil
70S initiation complex with assigned rRNA modifications from Staphylococcus aureus
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ...
Authors:Fatkhullin, B, Golubev, A, Khusainov, I, Yusupova, G, Yusupov, M.
Deposit date:2020-03-24
Release date:2021-01-27
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 angstrom resolution.
Febs Lett., 594, 2020
6MPI
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BU of 6mpi by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, DeMirci, H, Agris, P.F.
Deposit date:2018-10-07
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6YAN
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BU of 6yan by Molmil
Mammalian 48S late-stage translation initiation complex with histone 4 mRNA
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
6MKN
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BU of 6mkn by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, DeMirci, H, Agris, P.F.
Deposit date:2018-09-25
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
4LFA
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BU of 4lfa by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S rRNA, HYGROMYCIN B, MAGNESIUM ION, ...
Authors:Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T.
Deposit date:2013-06-26
Release date:2014-07-02
Method:X-RAY DIFFRACTION (3.6461 Å)
Cite:Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
to be published, 2013
4L47
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BU of 4l47 by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U on the Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Maehigashi, T, Dunkle, J.A, Dunham, C.M.
Deposit date:2013-06-07
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.220001 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
6Y69
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BU of 6y69 by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Wieland, M, Wilson, D.N.
Deposit date:2020-02-26
Release date:2020-07-01
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
6YBS
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BU of 6ybs by Molmil
Structure of a human 48S translational initiation complex - head
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-17
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
4LFZ
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BU of 4lfz by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U in the Absence of Paromomycin
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Maehigashi, T, Dunkle, J.A, Dunham, C.M.
Deposit date:2013-06-27
Release date:2014-08-06
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.92000055 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LF7
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BU of 4lf7 by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S rRNA, MAGNESIUM ION, PAROMOMYCIN, ...
Authors:Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T.
Deposit date:2013-06-26
Release date:2014-07-02
Method:X-RAY DIFFRACTION (3.1484 Å)
Cite:Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
To be Published, 2013
4L71
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BU of 4l71 by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-A on the Ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Maehigashi, T, Dunkle, J.A, Dunham, C.M.
Deposit date:2013-06-13
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.900001 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4KZZ
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BU of 4kzz by Molmil
Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A
Descriptor: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2013-05-30
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7.0305 Å)
Cite:The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
6MPF
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BU of 6mpf by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Cantara, W.A, DeMirci, H, Agris, P.F.
Deposit date:2018-10-05
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.
J.Mol.Biol., 432, 2020
6YAL
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BU of 6yal by Molmil
Mammalian 48S late-stage initiation complex with beta-globin mRNA
Descriptor: 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
4LF5
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BU of 4lf5 by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S rRNA, HYGROMYCIN B, MAGNESIUM ION, ...
Authors:Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T.
Deposit date:2013-06-26
Release date:2014-07-02
Method:X-RAY DIFFRACTION (3.753 Å)
Cite:Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
To be Published, 2013

221051

数据于2024-06-12公开中

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