4YO0
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![BU of 4yo0 by Molmil](/molmil-images/mine/4yo0) | Crystal structure of monoclonal anti-human podoplanin antibody NZ-1 with bound PA peptide | Descriptor: | 1,2-ETHANEDIOL, Heavy chain of antigen binding fragment, Fab, ... | Authors: | Fujii, Y, Kitago, Y, Arimori, T, Takagi, J. | Deposit date: | 2015-03-11 | Release date: | 2016-03-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state J.Cell.Sci., 129, 2016
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4YNY
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![BU of 4yny by Molmil](/molmil-images/mine/4yny) | Crystal structure of monoclonal anti-human podoplanin antibody NZ-1 | Descriptor: | Heavy chain of antigen binding fragment, Fab, Light chain of antigen binding fragment | Authors: | Fujii, Y, Kitago, Y, Arimori, T, Takagi, J. | Deposit date: | 2015-03-11 | Release date: | 2016-03-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.584 Å) | Cite: | Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state J.Cell.Sci., 129, 2016
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2Y5T
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![BU of 2y5t by Molmil](/molmil-images/mine/2y5t) | Crystal structure of the pathogenic autoantibody CIIC1 in complex with the triple-helical C1 peptide | Descriptor: | C1, CHLORIDE ION, CIIC1 FAB FRAGMENT HEAVY CHAIN, ... | Authors: | Dobritzsch, D, Lindh, I, Schneider, N, Uysal, H, Nandakumar, K.S, Burkhardt, H, Schneider, G, Holmdahl, R. | Deposit date: | 2011-01-17 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of an Arthritogenic Anticollagen Immune Complex. Arthritis Rheum., 63, 2011
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3IDY
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![BU of 3idy by Molmil](/molmil-images/mine/3idy) | Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab b13 heavy chain, Fab b13 light chain, ... | Authors: | Chen, L, Kwon, Y.D, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z.Y, Zhang, M.Y, Arthos, J, Burton, D.R, Dimitrov, D.S, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D. | Deposit date: | 2009-07-22 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science, 326, 2009
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5IT2
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![BU of 5it2 by Molmil](/molmil-images/mine/5it2) | Structure of a transglutaminase 2-specific autoantibody 693-10-B06 Fab fragment | Descriptor: | heavy chain, light chain | Authors: | Chen, X, Dalhus, B, Hnida, K, Iversen, R, Sollid, L.M. | Deposit date: | 2016-03-16 | Release date: | 2017-03-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions Nat. Med., 18, 2012
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8IVW
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![BU of 8ivw by Molmil](/molmil-images/mine/8ivw) | Crystal structure of NRP2 in complex with aNRP2-10 Fab fragment | Descriptor: | Heavy chian of antibody 10V8 Fab fragment, Light chain of antibody 10V8 Fab fragment, Neuropilin-2 | Authors: | Geng, Y, Zhai, L. | Deposit date: | 2023-03-29 | Release date: | 2023-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.205 Å) | Cite: | Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer. Sci Transl Med, 15, 2023
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8IVX
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![BU of 8ivx by Molmil](/molmil-images/mine/8ivx) | Crystal structure of NRP2 in complex with aNRP2-14 Fab fragment | Descriptor: | 1,2-ETHANEDIOL, Heavy chain of antibody 14V4 Fab fragment, Light chain of antibody 14V4 Fab fragment, ... | Authors: | Geng, Y, Zhai, L. | Deposit date: | 2023-03-29 | Release date: | 2023-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer. Sci Transl Med, 15, 2023
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1FOR
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![BU of 1for by Molmil](/molmil-images/mine/1for) | |
6UFT
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![BU of 6uft by Molmil](/molmil-images/mine/6uft) | |
1SBS
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![BU of 1sbs by Molmil](/molmil-images/mine/1sbs) | CRYSTAL STRUCTURE OF AN ANTI-HCG FAB | Descriptor: | MONOCLONAL ANTIBODY 3A2, SULFATE ION | Authors: | Fotinou, C, Beauchamp, J, Emsley, P, Dehaan, A, Schielen, W.J.G, Bos, E, Isaacs, N.W. | Deposit date: | 1998-04-08 | Release date: | 1999-04-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of an Fab fragment against a C-terminal peptide of hCG at 2.0 A resolution. J.Biol.Chem., 273, 1998
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1NIZ
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![BU of 1niz by Molmil](/molmil-images/mine/1niz) | NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody | Descriptor: | Exterior membrane glycoprotein(GP120) | Authors: | Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J. | Deposit date: | 2002-12-30 | Release date: | 2003-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Alternative Conformations of HIV-1 V3 Loops Mimic
beta Hairpins in Chemokines, Suggesting a Mechanism
for Coreceptor Selectivity. Structure, 11, 2003
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1NJ0
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![BU of 1nj0 by Molmil](/molmil-images/mine/1nj0) | NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody | Descriptor: | Exterior membrane glycoprotein(GP120) | Authors: | Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J. | Deposit date: | 2002-12-30 | Release date: | 2003-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Alternative Conformations of HIV-1 V3 Loops Mimic
beta Hairpins in Chemokines, Suggesting a Mechanism
for Coreceptor Selectivity. Structure, 11, 2003
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1IGJ
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![BU of 1igj by Molmil](/molmil-images/mine/1igj) | |
8RD2
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![BU of 8rd2 by Molmil](/molmil-images/mine/8rd2) | |
1IGI
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![BU of 1igi by Molmil](/molmil-images/mine/1igi) | |
3QSK
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![BU of 3qsk by Molmil](/molmil-images/mine/3qsk) | 5 Histidine Variant of the anti-RNase A VHH in Complex with RNAse A | Descriptor: | Engineered 5 Histidine anti-RNase A Camelid VHH Antibody Domain Variant, Ribonuclease pancreatic | Authors: | Murtaugh, M.L, Fanning, S.W, Sharma, T.M, Terry, A.M, Horn, J.R. | Deposit date: | 2011-02-21 | Release date: | 2011-08-10 | Last modified: | 2011-11-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A combinatorial histidine scanning library approach to engineer highly pH-dependent protein switches. Protein Sci., 20, 2011
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6ORN
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![BU of 6orn by Molmil](/molmil-images/mine/6orn) | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074 | Descriptor: | 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | Deposit date: | 2019-04-30 | Release date: | 2019-06-12 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
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3HI1
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![BU of 3hi1 by Molmil](/molmil-images/mine/3hi1) | Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F105 Heavy Chain, F105 Light Chain, ... | Authors: | Kwon, Y.D, Chen, L, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z, Zhang, M.-Y, Arthos, J, Burton, D.R, Dimitrov, D, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D. | Deposit date: | 2009-05-18 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science, 326, 2009
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6FFJ
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![BU of 6ffj by Molmil](/molmil-images/mine/6ffj) | |
4H0I
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![BU of 4h0i by Molmil](/molmil-images/mine/4h0i) | Crystal Structure of Scfv-2D10 in Complex with Methyl Alpha-D-Mannopyranoside | Descriptor: | 2D10 scFv, MAGNESIUM ION, methyl alpha-D-mannopyranoside | Authors: | Tapryal, S, Gaur, V, Kaur, K.J, Salunke, D.M. | Deposit date: | 2012-09-08 | Release date: | 2013-06-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural evaluation of a mimicry-recognizing paratope: plasticity in antigen-antibody interactions manifests in molecular mimicry. J.Immunol., 191, 2013
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4HGW
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![BU of 4hgw by Molmil](/molmil-images/mine/4hgw) | Crystal structure of S25-2 in complex with a 5,6-dehydro-Kdo disaccharide | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3,5-dideoxy-alpha-D-threo-oct-5-en-2-ulopyranosidonic acid, Antibody Fab fragment, heavy chain, ... | Authors: | Brooks, C.L, Evans, S.V. | Deposit date: | 2012-10-08 | Release date: | 2013-01-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide. Acta Crystallogr.,Sect.F, 69, 2013
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1F6L
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![BU of 1f6l by Molmil](/molmil-images/mine/1f6l) | VARIABLE LIGHT CHAIN DIMER OF ANTI-FERRITIN ANTIBODY | Descriptor: | ANTI-FERRITIN IMMUNOGLOBULIN LIGHT CHAIN | Authors: | Nymalm, Y, Kravchuk, Z, Salminen, T, Chumanevich, A.A, Dubnovitsky, A.P, Kankare, J, Pentikainen, O, Lehtonen, J, Arosio, P, Martsev, S, Johnson, M.S. | Deposit date: | 2000-06-22 | Release date: | 2002-10-23 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Antiferritin VL homodimer binds human spleen ferritin with high specificity J.STRUCT.BIOL., 138, 2002
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8WO0
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![BU of 8wo0 by Molmil](/molmil-images/mine/8wo0) | CryoEM structure of ZIKV rsNS1 filament | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1 | Authors: | Chew, B.L.A, Luo, D. | Deposit date: | 2023-10-06 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024
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8WO4
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![BU of 8wo4 by Molmil](/molmil-images/mine/8wo4) | ZIKV rsNS1 in complex with Fab EB9 and anti-fab nanobody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ... | Authors: | Chew, B.L.A, Luo, D. | Deposit date: | 2023-10-06 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024
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8WNP
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![BU of 8wnp by Molmil](/molmil-images/mine/8wnp) | |