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3T1B
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BU of 3t1b by Molmil
Crystal structure of the full-length AphB N100E variant
Descriptor: Transcriptional regulator, LysR family
Authors:Taylor, J.L, De Silva, R.S, Kovacikova, G, Lin, W, Taylor, R.K, Skorupski, K, Kull, F.J.
Deposit date:2011-07-21
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH.
Mol.Microbiol., 83, 2012
2UYE
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BU of 2uye by Molmil
Double mutant Y110S,F111V DntR from Burkholderia sp. strain DNT in complex with thiocyanate
Descriptor: GLYCEROL, REGULATORY PROTEIN, THIOCYANATE ION
Authors:Lonneborg, R, Smirova, I, Dian, C, leonard, G.A, McSweeney, S, Brzezinski, P.
Deposit date:2007-04-04
Release date:2007-08-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:In Vivo and in Vitro Investigation of Transcriptional Regulation by Dntr.
J.Mol.Biol., 372, 2007
5AE4
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BU of 5ae4 by Molmil
Structures of inactive and activated DntR provide conclusive evidence for the mechanism of action of LysR transcription factors
Descriptor: LYSR-TYPE REGULATORY PROTEIN, THIOCYANATE ION
Authors:Lerche, M, Dian, C, Round, A, Lonneborg, R, Brzezinski, P, Leonard, G.A.
Deposit date:2015-08-25
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Solution Configurations of Inactive and Activated Dntr Have Implications for the Sliding Dimer Mechanism of Lysr Transcription Factors.
Sci.Rep., 6, 2016
5AE5
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BU of 5ae5 by Molmil
Structures of inactive and activated DntR provide conclusive evidence for the mechanism of action of LysR transcription factors
Descriptor: GLYCEROL, LYSR-TYPE REGULATORY PROTEIN
Authors:Lerche, M, Dian, C, Round, A, Lonneborg, R, Brzezinski, P, Leonard, G.A.
Deposit date:2015-08-25
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.645 Å)
Cite:The Solution Configurations of Inactive and Activated Dntr Have Implications for the Sliding Dimer Mechanism of Lysr Transcription Factors.
Sci.Rep., 6, 2016
9HH1
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BU of 9hh1 by Molmil
LysR Type Transcriptional Regulator LsrB from Agrobacterium tumefaciens
Descriptor: Transcriptional regulator, LysR family
Authors:Elders, H, Schmidt, J.J, Fiedler, R, Hofmann, E, Narberhaus, F.
Deposit date:2024-11-20
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Two redox-responsive LysR-type transcription factors control the oxidative stress response of Agrobacterium tumefaciens.
Nucleic Acids Res., 53, 2025
3MZ1
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BU of 3mz1 by Molmil
The crystal structure of a possible TRANSCRIPTION REGULATOR PROTEIN from Sinorhizobium meliloti 1021
Descriptor: CHLORIDE ION, Putative transcriptional regulator
Authors:Tan, K, Xu, X, Cui, H, Chin, S, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-05-11
Release date:2010-06-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The crystal structure of a possible TRANSCRIPTION REGULATOR PROTEIN from Sinorhizobium meliloti 1021
To be Published
6XTV
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BU of 6xtv by Molmil
FULL-LENGTH LTTR LYSG FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND EFFECTOR ARG
Descriptor: ARGININE, Lysine export transcriptional regulatory protein LysG
Authors:Hofmann, E, Syberg, F, Schlicker, C, Eggeling, L, Schendzielorz, G.
Deposit date:2020-01-16
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Engineering and application of a biosensor with focused ligand specificity.
Nat Commun, 11, 2020
6XTU
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BU of 6xtu by Molmil
FULL-LENGTH LTTR LYSG FROM CORYNEBACTERIUM GLUTAMICUM
Descriptor: Lysine export transcriptional regulatory protein LysG
Authors:Hofmann, E, Syberg, F, Schlicker, C, Eggeling, L, Schendzielorz, G.
Deposit date:2020-01-16
Release date:2020-10-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Engineering and application of a biosensor with focused ligand specificity.
Nat Commun, 11, 2020
8Y6U
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BU of 8y6u by Molmil
Cryo-EM structure of E.coli transcription initiation complex with transcription factor GcvA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Shi, J.
Deposit date:2024-02-03
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:NMR analysis of a loop-bulge structure of UUCGA pentaloop.
Biochem.Biophys.Res.Commun., 691, 2024
1UTB
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BU of 1utb by Molmil
DntR from Burkholderia sp. strain DNT
Descriptor: ACETATE ION, GLYCEROL, LYSR-TYPE REGULATORY PROTEIN
Authors:Smirnova, I.A, Dian, C, Leonard, G.A, McSweeney, S, Birse, D, Brzezinski, P.
Deposit date:2003-12-05
Release date:2004-07-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Development of a Bacterial Biosensor for Nitrotoluenes: The Crystal Structure of the Transcriptional Regulator Dntr
J.Mol.Biol., 340, 2004
1UTH
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BU of 1uth by Molmil
DntR from Burkholderia sp. strain DNT in complex with Thiocyanate
Descriptor: LYSR-TYPE REGULATORY PROTEIN, THIOCYANATE ION
Authors:Smirnova, I.A, Dian, C, Leonard, G.A, McSweeney, S, Birse, D, Brzezinski, P.
Deposit date:2003-12-09
Release date:2004-07-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Development of a Bacterial Biosensor for Nitrotoluenes: The Crystal Structure of the Transcriptional Regulator Dntr
J.Mol.Biol., 340, 2004
2UYF
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BU of 2uyf by Molmil
Single mutant F111L DntR from Burkholderia sp. strain DNT in complex with thiocyanate
Descriptor: ACETATE ION, GLYCEROL, REGULATORY PROTEIN, ...
Authors:Lonneborg, R, Smirova, I, Dian, C, Leonard, G.A, Mcsweeney, S, Brzezinski, P.
Deposit date:2007-04-04
Release date:2007-08-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:In Vivo and in Vitro Investigation of Transcriptional Regulation by Dntr.
J.Mol.Biol., 372, 2007
5Y2V
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BU of 5y2v by Molmil
Strcutrue of the full-length CcmR complexed with 2-OG from Synechocystis PCC6803
Descriptor: 2-OXOGLUTARIC ACID, PHOSPHATE ION, Rubisco operon transcriptional regulator
Authors:Jiang, Y.L, Wang, X.P, Sun, H, Cheng, W, Han, S.J, Li, W.F, Chen, Y, Zhou, C.Z.
Deposit date:2017-07-27
Release date:2017-12-27
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1IZ1
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BU of 1iz1 by Molmil
CRYSTAL STRUCTURE OF CBNR, A LYSR FAMILY TRANSCRIPTIONAL REGULATOR
Descriptor: LysR-type regulatory protein
Authors:Muraoka, S, Okumura, R, Ogawa, N, Miyashita, K, Senda, T.
Deposit date:2002-09-18
Release date:2003-05-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of a Full-length LysR-type Transcriptional Regulator, CbnR: Unusual Combination of Two Subunit Forms and Molecular Bases for Causing and Changing DNA Bend
J.Mol.Biol., 328, 2003
1IXC
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BU of 1ixc by Molmil
Crystal structure of CbnR, a LysR family transcriptional regulator
Descriptor: LysR-type regulatory protein
Authors:Muraoka, S, Okumura, R, Ogawa, N, Miyashita, K, Senda, T.
Deposit date:2002-06-18
Release date:2003-06-18
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Full-length LysR-type Transcriptional Regulator, CbnR: Unusual Combination of Two Subunit Forms and Molecular Bases for Causing and Changing DNA Bend
J.Mol.Biol., 328, 2003
5Z7H
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BU of 5z7h by Molmil
Crystal structure of CcpE regulatory domain in citrate-bound form from Staphyloccocus aureus
Descriptor: CITRATE ANION, LysR family transcriptional regulator
Authors:Chen, J, Wang, L, Shang, F, Xu, Y.
Deposit date:2018-01-28
Release date:2018-02-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Citrate-responsive mechanism of catabolite control protein E from Staphyloccocus aureus
To Be Published
7QA0
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BU of 7qa0 by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound 1456
Descriptor: Multiple virulence factor regulator MvfR, ~{N}-[[2-(3-chloranyl-4-propan-2-yloxy-phenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-11-15
Release date:2022-11-23
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity
Ssrn, 2024
7QA3
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BU of 7qa3 by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound N-((2-(4-phenoxyphenyl)thiazol-5-yl)methyl)-2-(trifluoromethyl)pyridin-4-amine
Descriptor: Multiple virulence factor regulator MvfR, N-[[2-(4-phenoxyphenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-11-15
Release date:2022-11-23
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity
Ssrn, 2024
7QAV
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BU of 7qav by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound N-((2-(4-cyclopropylphenyl)thiazol-5-yl)methyl)-2-(trifluoromethyl)pyridin-4-amine
Descriptor: Multiple virulence factor regulator MvfR, ~{N}-[[2-(4-cyclopropylphenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-11-17
Release date:2022-11-30
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity
Ssrn, 2024
2H99
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BU of 2h99 by Molmil
Crystal structure of the effector binding domain of a BenM variant (R156H,T157S)
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C.
Deposit date:2006-06-09
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1.
Mol.Microbiol., 72, 2009
2H9B
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BU of 2h9b by Molmil
Crystal structure of the effector binding domain of a BenM variant (BenM R156H/T157S)
Descriptor: CHLORIDE ION, HTH-type transcriptional regulator benM, SULFATE ION
Authors:Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C.
Deposit date:2006-06-09
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1.
Mol.Microbiol., 72, 2009
7W06
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BU of 7w06 by Molmil
Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in complex with itaconate (SeMet labeled), Space group C121.
Descriptor: 2-methylidenebutanedioic acid, CHLORIDE ION, SULFATE ION, ...
Authors:Sun, P.K, Wang, B, Wang, Z.X, Qi, S, Li, X.J.
Deposit date:2021-11-17
Release date:2022-10-26
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages.
Nat Commun, 13, 2022
7W07
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BU of 7w07 by Molmil
Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in complex with itaconate, Space group C121.
Descriptor: 2-methylidenebutanedioic acid, SULFATE ION, Transcriptional regulator, ...
Authors:Sun, P.K, Wang, B, Li, X.J.
Deposit date:2021-11-17
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages.
Nat Commun, 13, 2022
7W08
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BU of 7w08 by Molmil
Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in APO form, Space group P1.
Descriptor: Transcriptional regulator, LysR family
Authors:Sun, P.K, Wang, B, Li, X.J.
Deposit date:2021-11-17
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages.
Nat Commun, 13, 2022
5Z72
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BU of 5z72 by Molmil
Crystal structure of CcpC regulatory domain in complex with citrate from Bacillus amyloliquefaciens
Descriptor: CITRATE ANION, CcpC, SODIUM ION
Authors:Chen, J, Wang, L, Shang, F, Xu, Y.
Deposit date:2018-01-26
Release date:2018-02-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanistic insights from the crystal structures of a catabolite control protein C on citrate-responsive mechanism
To Be Published

238895

数据于2025-07-16公开中

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