5AE4

Structures of inactive and activated DntR provide conclusive evidence for the mechanism of action of LysR transcription factors

Summary for 5AE4

• Entry DOI: 10.2210/pdb5ae4/pdb
• Related: 5AE5
• Descriptor: LYSR-TYPE REGULATORY PROTEIN, THIOCYANATE ION (2 entities in total)
• Functional Keywords: transcription, lysr-type transcription regulators, lttr, transcription factor, helix-turn-helix, dna binding protein, rossmann-like fold, autoinducing mutant, h169t-dntr
• Biological source: BURKHOLDERIA CEPACIA
• Total number of polymer chains: 2
• Total formula weight: 69786.65

Authors

Lerche, M.,Dian, C.,Round, A.,Lonneborg, R.,Brzezinski, P.,Leonard, G.A. (deposition date: 2015-08-25, release date: 2016-01-13, Last modification date: 2024-01-10)

• Primary citation: Lerche, M.,Dian, C.,Round, A.,Lonneborg, R.,Brzezinski, P.,Leonard, G.A.; The Solution Configurations of Inactive and Activated Dntr Have Implications for the Sliding Dimer Mechanism of Lysr Transcription Factors.; Sci.Rep., 6:19988-, 2016; PubMed: 26817994; DOI: 10.1038/SREP19988

Experimental method

X-RAY DIFFRACTION (3.3 Å)